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| 1 | Hepatitis C virus-related B cell subtypes in non Hodgkin's lymphoma显示文摘AIM:To evaluate if indolent B cell-non Hodgkin's lymphoma(B-NHL) and diffuse large B-cell lymphoma(DLBCL) in hepatitis C virus(HCV) positive patients could have different biological and clinical characteristics requiring different management strategies.METHODS:A group of 24 HCV related B-NHL patients(11 indolent,13 DLBCL) in whom the biological and clinical characteristics were described and confronted.Patients with DLBCL were managed with the standard of care of treatment.Patients with indolent HCV-related B-NHL were managed with antiviral treatment pegylated interferon plus ribavirin and their course observed.The outcomes of the different approaches were compared.RESULTS:Patients with DLBCL had a shorter duration of HCV infection and a higher prevalence of HCV genotype 1 compared to patients with indolent B-NHL in which HCV genotype 2 was the more frequent genotype.Five of the 9 patients with indolent HCV-relatedB-NHL treated with only antiviral therapy,achieved a complete response of their onco-haematological disease(55%).Seven of the 13 DLBCL patients treated with immunochemotheraphy obtained a complete response(54%).CONCLUSION:HCV genotypes and duration of HCV infection differed between B-NHL subtypes.Indolent lymphomas can be managed with antiviral treatment,while DLBCL is not affected by the HCV infection. | Adriano M Pellicelli Massimo Marignani Valerio Zoli Mario Romano Aldo Morrone Lorenzo Nosotti Giuseppe Barbaro Antonio Picardi Umberto Vespasiani Gentilucci Daniele Remotti Cecilia D'Ambrosio Caterina Furlan Fabrizio Mecenate Ettore Mazzoni Ignazio Majolino Roberto Villani Arnaldo Andreoli Giorgio Barbarini | 2011 | World Journal of Hepatology2011，3，11： | 4 |
| 2 | Statin use and cognitive function in middle-aged adults with type 1 diabetes显示文摘AIM To test associations between statin use and cognitive impairment in adults with childhood-onset type 1 diabetes(T1D).METHODS In 2010-13, n = 108 middle-aged participants from ongoing observational Pittsburgh Epidemiology of Diabetes Complications Study underwent neurocognitive assessment(mean age and T1 D duration of 49 and 41 years, respectively). All were diagnosed with childhoodonset(i.e., prior to age 18) T1 D between 1950 and 1980 and were seen within one year of diagnosis at Children's Hospital of Pittsburgh. Self-reported statin use(yes/no and if yes, name of statin) was collected biennially from parent study baseline(1986-1988) to time of neurocognitive testing. Logistic regression models tested associations between statin use groups and cognitive impairment(defined as having two or more cognitive test scores 1.5SD or worse than published norms) while linear regression models tested associations between statin use groups and cognitive domain z-scores(domains: Verbal IQ, memory, executive function, psychomotor speed, and visuo-construction). All models controlled for education and age. To address confounding by indication, models were repeated using a propensity score for statin use.RESULTS Of the 108 participants, 51 reported never using statins. Median duration of statin use among the 57 ever users was 6 years. These 57 ever statin users were split to create two groups(≤ or > median years of statin use): 1-6 years(n = 25), and 7-12 years(n = 32). Compared with never users, using statins 1-6 years tripled the odds of cognitive impairment(OR = 3.16; 95%CI: 0.93-10.72; P = 0.06) and using statins 7-12 years almost quintupled the odds of cognitive impairment(OR = 4.84; 95%CI: 1.63-14.44; P = 0.005). Compared with never users, using statins 1-6 or 7-12 years was related to worse performance in the memory domain(β =-0.52; P = 0.003, and-0.39; P = 0.014, respectively). Adjusting for coronary artery disease, low density lipoprotein cholesterol, and Apo E4 status did not substantially alter results, and none of these covariates were significantly related to cognitive outcomes(all P > 0.05). Propensity score analyses support that associations between poor cognitive outcomes and statin use were not due merely to confounding by indication. CONCLUSION Statin use was associated with cognitive impairment, particularly affecting memory, in these middle-aged adults with childhood-onset T1 D, whom at this age, should not yet manifest age-related memory deficits. | Karen A Nunley Trevor J Orchard Christopher M Ryan Rachel Miller Tina Costacou Caterina Rosano | 2017 | World Journal of Diabetes2017，8，6： | 2 |
| 3 | The capsaicinreceptor:Aheat-acfivateclion channel in the pain pathway显示文摘 | CATERINA M J SCHUMACHER M A TOMINAGA M | 1997 | Nature1997，389，： | 1 |
| 4 | Survivin gene expression in early-stage non-small cell lung cnacer 显示文摘 | Monica F Caterina P Antonio M | 2003 | Pathology2003，200，3： | 1 |
| 5 | Development of a multiplex PCR for detection of avian adeno virus , avian reovirus , infectious bursal , disease virus and chicken anemia virus 显示文摘 | Caterina K M Frasea S J R Girshick | 2004 | Molecular Cellular Probes2004，18，： | 1 |
| 6 | The capsaicin receptor: a heat-activated ion channel in the pain pathway显示文摘 | Caterina MJ Schumacher MA Tominaga M | 1997 | Nature1997，389，6653： | 1 |
| 7 | Global distribution of shigella sonnei clones显示文摘 | Ingrid FT Caterina M Peter GS | 2011 | Emerg lnfect Dis2011，17，10： | 1 |
| 8 | Short- Versus Long-Term Duration of Dual-Antiplatelet Therapy After Coronary Stenting: A Randomized Multicenter Trial显示文摘 | Marco Valgimigli Gianluca Campo Monia Monti Pascal Vranckx Gianfranco Percoco Carlo Tumscitz Fausto Castriota Federico Colombo Matteo Tebaldi Giuseppe Fucà Moh?d Kubbajeh Elisa Cangiano Monica Minarelli Antonella Scalone Caterina Cavazza Alice Frangione M | 2012 | Circulation2012，，16： | 1 |
| 9 | Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana ( Botrytis cinerea ) resistant to QoI fungicides显示文摘 | Rita M De Miccolis Angelini Caterina Rotolo Mario Masiello Stefania Pollastro Hideo Ishii Francesco Faretra | 2012 | Pest Manag Sci2012，，9： | 1 |
| 10 | The capsaicin receptor:a heat-activated ion channel in the pain pathway显示文摘 | Caterina MJ Schumacher MA Tominaga M | 1997 | Nature1997，389，： | 1 |
| 11 | The capsaicin receptor: a heat-activated ion channel in the pain pathway 显示文摘 | Caterina MJ Schumacher MA Tominaga M | 1997 | Nature1997，389，6653： | 1 |
| 12 | Biodegradable biliary stent implantation in the treatment of benign bilioplastic-refractory biliary strictures: Preliminary experience显示文摘 | GIOVANNI M CATERINA M FABIO M | 2013 | European Radiology2013，23，12： | 1 |
| 13 | Functional Brain Reorganization in Multiple Sclerosis: Evidence from fMRI Studies 显示文摘 | Patrizia P Caterina M Francesca C | 2006 | J Neuroimag2006，16，2： | 1 |
| 14 | Impaired nociception and pain sensation in mice lacking the capsaicin receptor显示文摘 | Caterina M J Leffler A Malmberg AB | | 0，，03： | 1 |
| 15 | Transient receptor potential ion channels as partici- pants in thermosensation and thermoregulation 显示文摘 | Caterina M J | 2007 | Am J Physiol Regul Integr Comp Physiol2007，292，： | 1 |
| 16 | The capsaicin receptor: a heat-activated ion channel in the pain pathway显示文摘 | Caterina MJ Schumacher MA Tominage M | 1997 | Nature1997，389，6653： | 1 |
| 17 | The capsaicin receptor:a heat-activated ion channel in the pain pathway显示文摘 | Caterina MJ Schumacher MA Tominaga M | 1997 | Nature1997，398，： | 1 |
| 18 | The cloned capsaicin receptor integrates multiple pain - producing stimuli 显示文摘 | Tominaga M Caterina MJ Malmberg AB | 1998 | Neuron1998，21，3： | 1 |
| 19 | Thermosensation and pain显示文摘 | Tominaga M Caterina MJ | | 0，，01： | 1 |
| 20 | The capsaicin receptor: a heat-activated ion channel in the pain pathway 显示文摘 | Caterina M J Schumacher MA Tominaga M | 1997 | Nature1997，389，6653： | 1 |
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