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| 1 | 凝血酶肽类对创面愈合及表皮细胞增生与移行的作用研究显示文摘目的探讨新合成的凝血酶受体激活肽 TP508对创面愈合及表皮细胞增生与移行的作用。方法SD大鼠 18只,麻醉下在每一大鼠背部作 4个直径 1.5 cm圆形皮肤切除创面。 TP508治疗组 9只大鼠,每 1创面用 TP508 0.1μg(40ml)治疗。对照组9只大鼠用40μl等渗盐水处理。用 JAVA Jandel和 IMAGE PRO图形处理软件计算创面面积。人表皮细胞NHEK945增生采用MTT测定法和细胞计数仪直接计数法。细胞移行实验采用48孔 Boyden细胞移行测定板进行,移行至滤膜下表面的细胞数以斑点密度表示。结果术后 7 d和 14 d,TP508处理组创面面积分别为盐水组的73.7%和45.4%(P<0.01)。凝血酶、TP508显著促进表皮细胞增生。培养液组细胞移行斑点密度为 76.6±13.8,添加 1μg/ml凝血酶和 10 μg/ml TP508,其斑点密度分别增至 104.4±12.2和109.4±14.6。结论凝血酶及TP508对大鼠皮肤切除创面愈合及人表皮细胞增生与移行均有显著作用,后者在一定程度上解释了TP508促进创面愈合的机理。 | 黄跃生 杨宗城 黎鳌 DH Carney | 2000 | 中华烧伤杂志2000,16,1: | 5 |
| 2 | The Role of the Operating Room Nurse Manager in the Successful Implementation of Preoperative Briefings and Postoperative Debriefings in the VHA Medical Team Training Program显示文摘 | Lori D. Robinson Douglas E. Paull Lisa M. Mazzia Lisa Falzetta James Hay Julia Neily Peter D. Mills Brian Carney James P. Bagian | 2010 | Journal of PeriAnesthesia Nursing2010,,: | 2 |
| 3 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018,9,11: | 2 |
| 4 | Hyperopia is predominantly axial in nature显示文摘 | Strang NC Schmid KL Carney LC | 1998 | Curr Eye Res1998,17,4: | 2 |
| 5 | Principles for retrofitting coal burners for oxy-combustion显示文摘 | Andrew Fry Brad Adams Alan Paschedag Paul Kazalski Casey Carney Danylo Oryshchyn Rigel Woodside Steve Gerdemann Thomas Ochs | 2011 | International Journal of Greenhouse Gas Control2011,,: | 2 |
| 6 | Depression as a Risk Factor for Poor Prognosis Among Patients With Acute Coronary Syndrome: Systematic Review and Recommendations: A Scientific Statement From the American Heart Association显示文摘 | Judith H. Lichtman Erika S. Froelicher James A. Blumenthal Robert M. Carney Lynn V. Doering Nancy Frasure-Smith Kenneth E. Freedland Allan S. Jaffe Erica C. Leifheit-Limson David S. Sheps Viola Vaccarino Lawson Wulsin | 2014 | Circulation2014,,12: | 2 |
| 7 | Clinical depression and inflammatory risk markers for coronary heart disease 显示文摘 | Miller GE Stetler CA Carney RM | 2002 | Am J Cardiol2002,90,12: | 1 |
| 8 | Change in heart rate and heart rate variability during treatment for de pression in patients with coronary artery disease显示文摘 | Freedland KE Stein PK | 2000 | Psychosom Med2000,62,5: | 1 |
| 9 | Acetabular dysplasia following closed reduction of developmental dislocation of the hip显示文摘 | Carney BT | 2005 | J Surg Orthop Adv2005,3,: | 1 |
| 10 | Evaluation of mammography performance in the United States: the Breast Cancer Surveillance Consortium显示文摘 | Yabroff KR Ballard-Barbash R Carney P | 2007 | Semin Breast Dis2007,10,2: | 1 |
| 11 | Sex determination in the Monoecious Species cucumber is confined to specific floral whorls显示文摘 | Kartin M Kater John Franken Kim J Carney | 2001 | The Plant Cell2001,13,: | 1 |
| 12 | High strain lagrangian hydrodynamics,a three dimensional SPH code for dynamic material response显示文摘 | LIBERSKY L D PETSCHECK A G CARNEY T C | 1993 | Journal of Computational Physics1993,109,: | 1 |
| 13 | Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses显示文摘 | Jaslow CR Carney JL Kutteh WH | 2010 | Fertil Streril2010,93,4: | 1 |
| 14 | Business group affiliation, performance, context, and strategy: A recta- analysis显示文摘 | Carney M Gedajlovic E R Heugens P P | 2011 | Academy of Management Journal2011,54,3: | 1 |
| 15 | Cryptic processes in the sea: A review of dehyed development in the micro- scopic life stages of marine macroalgae 显示文摘 | Carney L T Edwards M S | 2006 | Algae2006,21,2: | 1 |
| 16 | Adrenal lymphangio ma: clinieopathologie and immunohistochemical characteris tics of a rare lesion 显示文摘 | Ellis CL Banerjee P Carney E | 2011 | HumPathol2011,42,: | 1 |
| 17 | Elevated serum creatine kinase BB levels in patients with small cell lung cancer显示文摘 | Carney DN Zweig MH Ihde DC | 2004 | Cancer Res2004,44,11: | 1 |
| 18 | Chronic in vivo testing of the Penn State infant ventricular assist device显示文摘 | Weiss WJ Carney EL Clark JB | | 0,,01: | 1 |
| 19 | A trial of intracranial- pressure monitoring in traumatic brain injury 显示文摘 | Chesnut RM Temkin N Carney N | 2012 | N Engl J Med2012,367,26: | 1 |
| 20 | Direct investiga- tion of intraeellular presence of gold nanoparticles via photother- mal hetemdyne imaging 显示文摘 | LEDUC C JUNG J M CARNEY R P | 2011 | Acs Nano2011,5,4: | 1 |