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1《过敏性鼻炎及其对哮喘的影响(ARIA)》指南2019版过敏性鼻炎管理路径(中国版)显示文摘2018年12月3日,慢性疾病管理大会在巴黎召开,经过与会的过敏科学及气道疾病领域的专家和患者组织讨论,针对未来鼻炎和哮喘的管理,推荐采用真实世界综合管理路径评估系统,旨在实现数字化、综合化、以人为本的管理。本文是该文件的摘要版,其中也介绍了中国过敏性鼻炎和哮喘的流行状况以及《过敏性鼻炎及其对哮喘的影响》(ARIA)在中国应用的具体情况。Bachert C Fokkens WJ Haahtela T Hellings PH Klimek L Papadopoulos N Pham-Thi N PfaarO Valiulis A Ventura MT Onorato G Czarlewski W Bedbrook A Bousquet J 王向东(编译) 王成硕(编译) 郑铭(编译) 杜崑(编译) 张罗(编译) 2019中国耳鼻咽喉头颈外科2019,26,12:23
2澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) 2019中国脑血管病杂志2019,16,4:9
3Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists显示文摘Grommes C Landreth GE Heneka MT 2004Lancet Oncol2004,5,:2
4Chlamydia trachomatis:genome sequence analysis of lymphogranuloma venereum isolates显示文摘Thomson NR Holden MT Carder C 2008Genome Res2008,18,1:1
5Prevention of cortisteroid - induced bone loss with nitric oxide donor nitroglycerin in male rats显示文摘 Cgqpa MT Yallampalli C 1997Bone1997,21,:1
6Pregnancy-associated plasma protein-A (PAPP-A) in ovine,bovine,porcine,and equine ovarian follicles:involvement in IGF binding protein-4 proteolytic degradation and mRNA expression during follicular development显示文摘 Overgaard MT Oxvig C 2001Endocrinology2001,142,:1
7Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J 2004Proc Natl Acad Sci USA2004,101,26:1
8An integrated decision-tree testing strategy for eye irritation with respect to the requirements ofthe EU REACH legislation显示文摘Grindon C Combes R Cronin MT 2008Altern Lab Anim2008,,:1
9Protection of mouse photoreceptors by survival factors in retinal degeneration 显示文摘Lavail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH 1998Invest Ophthalmol Vis Sci1998,39,3:1
10Protection of mouse photoreceptors by survival factors in retinal degenerations 显示文摘LaVail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH Steinberg RH 1998Invest Ophthalmol Vis Sci1998,39,3:1
11CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers 显示文摘Donato MT Viitala P Rodriguez-Antona C 2000Drug Metab Dispos2000,28,11:1
12Stealth PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system 显示文摘Bazile D Prud' Homme C Bassoulet MT 1995J Pharm Sci1995,84,4:1
13Cervical ripening before operative hysteroscopy in premenopausal women: a randomized, double - blind, placebo - controlled comparison of vaginal and oral misoprostol 显示文摘Batukan C Ozgun MT Ozcelik B 2008Fertil Steri12008,89,:1
14Influence of low glucose supply on the regulation of gene expression by nucleus pulposus cells and their responsiveness to mechanical loading显示文摘Rinkler C Heuer F Pedro MT 2010J Neurosurg Spine2010,13,4:1
15Peripheral expression of key regulatory kinases in Alzheimer's disease and Parkinson' s disease显示文摘Armentero MT Sinforiani E Ghezzi C 2011Neurobiol Aging2011,32,12:1
16miR-21 as a key regulator of oncogenic proceses显示文摘Selcuklu SD Donoghue MT Spilane C 2009Biochem Soc Trans2009,37,4:1
17The Telemedical Res- cue Assistance System ' TemRas' -- Development, First Results, and Impact显示文摘BUscher C Eisner J Schneiders MT 2014Biomed Eng2014,59,2:1
18Firsttrimesterdiagnosis of sacrococcygeal teratoma usingtwo-and three-dimensionalultrasound显示文摘Batukan C Ozgun MT Basbug M 2011ClinUltrasound2011,39,3:1
19miR-21 as a key regulator of oneogenic processes显示文摘SELCUKLU SD DONOGHUE MT SPILLANE C 2009Biochem Soc Trans2009,37,4:1
20Elevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute steoke显示文摘Foerch C Wunderlich MT Dvorak F 2007Stroke2007,38,9:1
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