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| 1 | Role of receptor tyrosine kinases in gastric cancer: New targets for a selective therapy显示文摘受体酷氨酸家族 ases (RTK ) 象表皮的生长因素受体家庭那样包括增长和变形传播参予肿瘤形成的几步。几已知的 RTK 起来在是主要的胃的癌症调整了定制的治疗的目标。仅仅初步的数据然而,在使用上存在当前临床上可得到的药象在胃的癌症的背景的 trastuzumab, cetuximab, bevacizumab, gefitinib, erlotinib,和 imatinib 那样。现出症状之前的潜的数据建议他们的使用的一个潜在的好处,特别在有“常规”的抑制细胞的联合治疗。这评论象新途径和药一样在癌症治疗关于他们的使用总结当前的知识优化治疗成功。 | JC Becker C Müller-Tidow H Serve W Domschke T Pohle | 2006 | World Journal of Gastroenterology2006，12，21： | 19 |
| 2 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 3 | Method development for the determination of cadmium in fertilizer samples using high-resolution continuum source graphite furnace atomic absorption spectrometry and slurry sampling显示文摘 | Aline R. Borges Emilene M. Becker Céline Lequeux Maria Goreti R. Vale Sergio L.C. Ferreira Bernhard Welz | 2011 | Spectrochimica Acta Part B: Atomic Spectroscopy2011，，7： | 3 |
| 4 | Evaluating the performance of biologically active rapid filters 显示文摘 | Lechevallier M W William C Becker Paul Schorr | 1992 | J AWWA1992，84，4： | 2 |
| 5 | Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘 | D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik | 2008 | Ultraschall in Med2008，，05： | 2 |
| 6 | Development of bioinformatic tools to support EST-sequencing, in silico and microarray-based transcriptome profiling in mycorrhizal symbioses 显示文摘 | KUSTER H BECKER A FIRNHABER C | 2007 | Phytochemistry2007，68，1： | 1 |
| 7 | Optimal Contrast Application for Cardiac 4-detector row Computed Tomography显示文摘 | Becker CR Hong C Knez A | 2003 | Invest Radiol2003，38，11： | 1 |
| 8 | Different types of scaffolds for reconstruction of the urinary tract by tissue engineering显示文摘 | Brehmer B Rohrmann D Becker C | 2007 | Urol Int2007，78，1： | 1 |
| 9 | Human glandular kallikrein 2: a potential serum marker for predicting the organ confined versus nonorgan confined growth of prostate cancer显示文摘 | Haese A Becker C Noldus J | 2000 | J Urol2000，163，5： | 1 |
| 10 | Identification of a novel coronavirus in patients with severe acute respiratory syndrome显示文摘 | Drosten C Gunther S Preiser W van der Werf S Brodt HR Becker S | 2003 | N Engl J Med2003，348，： | 1 |
| 11 | Hypoglycemia in cbildren with diabetes mellitus risk factors, cognitive function and management显示文摘 | RYAN C BECKER | 1999 | Pediatric Endocrinology1999，28，： | 1 |
| 12 | Role of NF-kappaB in im- mune and inflammatory responses in the gut显示文摘 | Neurath MF Becker C Barbulescu K | 1998 | Gut1998，43，6： | 1 |
| 13 | CT of coronary artery disease显示文摘 | SCHOEPF U J BECKER C R OHNESORGE B M | 2004 | Radiology2004，23，1： | 1 |
| 14 | Nuclear translocation of papillomavirus minor capsid protein L2 requires Hsc70显示文摘 | Florin L Becker K A Sapp C | 2004 | J Virol2004，78，11： | 1 |
| 15 | Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-anal- ysis 显示文摘 | Chu S G Becker R C Berger P B | 2010 | J Thromb Haemost2010，8，1： | 1 |
| 16 | German Environmental Sur- vey 1998 (GerES III): environmental pollutants in the urine of the German population显示文摘 | Becker K Schulz C Kaus S | 2003 | Int J Hyg Environ Health2003，206，1： | 1 |
| 17 | Costimulatory molecules in human atherosclerotic plaques: an indication of antigen specific T lymphocyte activation显示文摘 | Onno J de Boer Floris Hirsch Allard C van der Wal Chris M van der Loos Pranab K Das Anton E Becker | 1997 | Atherosclerosis1997，，2： | 1 |
| 18 | Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea显示文摘 | Becker ML Aarnoudse AJ Newton-Cheh C | | 0，，07： | 1 |
| 19 | Frontal substructures within the planetary boundary layer显示文摘 | Andreas Becker Helmut Kraus C?cilia M. Ewenz | 1996 | Boundary - Layer Meteorology (-)1996，，1： | 1 |
| 20 | Minimum criteria for immediate provisionalization of single-tooth dental implants in extraction sites:a 1-year retrospective study of 100 consecutive cases显示文摘 | BECKER C M WILSON T J JENSEN O T | 2011 | J Oral Maxillofac Surg2011，69，2： | 1 |
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