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| 1 | Clinical characteristics of incidental or unsuspected gallbladder cancers diagnosed during or after cholecystectomy: A systematic review and meta-analysis显示文摘AIM: To perform a systematic review of incidental or unsuspected gallbladder(GB) cancer diagnosed during or after cholecystectomy. METHODS: Data in Pub Med, EMBASE, and CochraneLibrary were reviewed and 26 publications were included in the meta-analysis. The inclusion criterion for incidental GB cancer was GB cancer diagnosed during or after cholecystectomy that was not suspected at a preoperative stage. Pooled proportions of the incidence, distribution of T stage, and revisional surgery of incidental GB cancer were analyzed.RESULTS: The final pooled population comprised 2145 patients with incidental GB cancers. Incidental GB cancers were found in 0.7% of cholecystectomies p e r f o r m e d f o r b e n i g n g a l l b l a d d e r d i s e a s e s o n preoperative diagnosis(95%CI: 0.004-0.012). Nearly 50% of the incidental GB cancers were stage T2 with a pooled proportion of 47.0%(95%CI: 0.421-0.519). T1 and T3 GB cancers were found at a similar frequency, with pooled proportions of 23.0%(95%CI: 0.178-0.291) and 25.1%(95%CI: 0.195-0.317), respectively. The pooled proportion that completed revisional surgery for curative intent was 40.9%(95%CI: 0.329-0.494). The proportion of patients with unresectable disease upon revisional surgery was 23.0%(95%CI: 0.177-0.294). CONCLUSION: A large proportion of incidental GB cancers were T2 and T3 lesions. Revisional surgery for radical cholecystectomy is warranted in T2 and more advanced cancers. | Kui Sun Choi Sae Byeol Choi Pyoungjae Park Wan Bae Kim Sang Yong Choi | 2015 | World Journal of Gastroenterology2015，21，4： | 24 |
| 2 | Effects of Salvia miltiorrhiza Bunge extract and its single components on monosodium urate-induced pain in vivo and lipopolysaccharide-induced inflammation in vitro显示文摘OBJECTIVE:To investigate the possible antinociceptive effects of Salvia(S.)miltiorrhiza Bunge and its single components in monosodium urate(MSU)-induced pain model in mice and lipopolysaccharide(LPS)-induced inflammation model in RAW264.7 cells.METHODS:Pretreatment of S.miltiorrhiza Bunge extract(from 1 to 50μg/mL)concentration-dependently attenuated LPS-induced nitric oxide(NO)release.The extract of S.miltiorrhiza Bunge(50 or 100 mg/kg)also caused reversals of decreased threshold for pain in the MSU-treated group as measured by Von-Frey test.Furthermore,we assessed the antinociceptive and anti-inflammatory properties of the active single components from S.miltiorrhiza Bunge such as 15,16-dihydrotanshinoneⅠ,tanshinoneⅠ,cryptotanshinone,miltirone,tanshinoneⅡA,and salvianolic acid B.Some of them showed an anti-inflammatory effect in LPS-induced NO release model and an antinociceptive effect in MSU-treated pain model.RESULTS:Our results suggest that S.miltiorrhiza Bunge extract may exert anti-inflammatory effect by reducing LPS-induced NO release and an antinociceptive property in MSU-treated pain model.Especially,tanshinoneⅡA,miltirone,cryptotanshinone,and 15,16-dihydrotanshinoneⅠ,not only appear to be responsible for LPS-induced NO release induced by S.miltiorrhiza Bunge,but also in the production of S.miltiorrhiza Bunge extract-induced antinociception in MSU-treated pain model.CONCLUSION:Therefore,the analgesic and anti-inflammatory property of S.miltiorrhiza Bunge indicate it as a therapeutic potential candidate for the treatment of pain and inflammation. | FENG Jinghui Set Byeol Kim Hee Jung Lee Su Min Sim Soon Sung Lim Hong Won Suh | 2021 | Journal of Traditional Chinese Medicine2021，41，2： | 4 |
| 3 | Outcome after curative resection for a huge (≥10 cm) hepatocellular carcinoma and prognostic significance of gross tumor classification显示文摘 | Gi Hong Choi Dai Hoon Han Dong Hyun Kim Sae Byeol Choi Chang Moo Kang Kyung Sik Kim Jin Sub Choi Young Nyun Park Jun Yong Park Do Young Kim Kwang-Hyub Han Chae Yoon Chon Woo Jung Lee | 2009 | The American Journal of Surgery2009，，5： | 2 |
| 4 | Surgical strategy for T2 and T3 gallbladder cancer: is extrahepatic bile duct resection always necessary?显示文摘 | Sae Byeol Choi Hyung Joon Han Wan Bae Kim Tae Jin Song Sung Ock Suh Sang Yong Choi | 2013 | Langenbeck’s Archives of Surgery2013，，8： | 1 |
| 5 | Clinicopathological Analysis and Survival outcome of Duodenal Adenocarcinoma显示文摘 | Myung Jin Kim Sae Byeol Choi Hyung Joon Han Pyoung Jae Park Wan Bae Kim Tae Jin Song Sung Ock Suh Sang Yong Choi | 2013 | Kaohsiung Journal of Medical Sciences2013，，： | 1 |
| 6 | Incidental Gallbladder Cancer Diagnosed Following Laparoscopic Cholecystectomy显示文摘 | Sae Byeol Choi Hyung Joon Han Chung Yun Kim Wan Bae Kim Tae-Jin Song Sung Ock Suh Young Chul Kim Sang Yong Choi | 2009 | World Journal of Surgery2009，，12： | 1 |
| 7 | Nonconvulsive status epilepticus disguising as hepatic encephalopathy显示文摘Nonconvulsive status epilepticus has become an important issue in modern neurology and epileptology.This is based on difficulty in definitively elucidating thecondition and its various clinical phenomena and on our inadequate insight into the intrinsic pathophysiological processes.Despite nonconvulsive status epilepticus being a situation that requires immediate treatment,this disorder may not be appreciated as the cause of mental status impairment.Although the pathophysiology of nonconvulsive status epilepticus remains unknown,this disorder is thought to lead to neuronal damage,so its identification and treatment are important.Nonconvulsive status epilepticus should be considered in the differential diagnosis of patients with liver cirrhosis presenting an altered mental status.We report a case of a 52-year-old male with liver cirrhosis presenting an altered mental status.He was initially diagnosed with hepatic encephalopathy but ultimately diagnosed with nonconvulsive status epilepticus by electroencephalogram. | Yong Min Jo Sung Wook Lee Sang Young Han Yang Hyun Baek Ji Hye Ahn Won Jong Choi Ji Young Lee Sang Ho Kim Byeol A Yoon | 2015 | World Journal of Gastroenterology2015，21，16： | 1 |
| 8 | Incidental Gallbladder Cancer Diagnosed Following Laparoscopic Cholecystectomy显示文摘 | Sae Byeol Choi Hyung Joon Han Chung Yun Kim Wan Bae Kim Tae-Jin Song Sung Ock Suh Young Chul Kim Sang Yong Choi | 2009 | World Journal of Surgery2009，，12： | 1 |
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