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    题名 作者 年代 出处 被引量
1Elastography-based screening for esophageal varices in patients with advanced chronic liver disease显示文摘Elastography-based liver stiffness measurement(LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease(ACLD). The presence of varices and especially of varices needing treatment(VNT) indicates distinct prognostic stages in patients with compensated ACLD(cACLD). The Baveno VI guidelines suggested a simple algorithm based on LSM < 20 kPa(by transient elastography, TE) and platelet count > 150 G/L for ruling-out VNT in patients with cACLD. These(and other) TE-based LSM cut-offs have been evaluated for VNT screening in different liver disease etiologies. Novel point shear-wave elastography(pSWE) and two-dimensional shear wave elastography(2D-SWE) methodologies for LSM have also been evaluated for their ability to screen for 'any' varices and for VNT. Finally, the measurement of spleen stiffness(SSM) by elastography(mainly by pSWE and 2D-SWE) may represent another valuable screening tool for varices. Here, we summarize the current literature on elastography-based prediction of 'any' varices and VNT. Finally,we have summarized the published LSM and SSM cut-offs in clinically useful scale cards.Rafael Paternostro Thomas Reiberger Theresa Bucsics 2019World Journal of Gastroenterology2019,25,3:20
2Non-selective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis显示文摘Mattias Mandorfer Simona Bota Philipp Schwabl Theresa Bucsics Nikolaus Pfisterer Matthias Kruzik Michael Hagmann Alexander Blacky Arnulf Ferlitsch Wolfgang Sieghart Michael Trauner Markus Peck-Radosavljevic Thomas Reiberger 2014Gastroenterology2014,,:3
3肝硬化腹水患者肝肾综合征与特殊原因所致急性肾功能不全的比较显示文摘肝肾综合征是发生在肝硬化腹水患者中、表现为肾损伤的综合征,其发病机制尚不明确。维也纳大学医学院的Bucsics等纵向观察了肝硬化腹水的肾损伤患者,将血肌酐增加了1倍或增加至≥1.5 mg/dl诊断为肝肾综合征。如果发现了特殊诱发原因(肾毒素、肾实质损伤、血容量减低、感染)就诊断为特殊因素所致急性肾损伤。研究纳入497例肝硬化患者,其中71例为肝肾综合征,84例为特殊因素导致急性肾损伤。Bucsics T 陈晓倩 李婉玉 2016临床肝胆病杂志2016,32,7:3
4急性肾损伤和肝肾综合征:肝硬化中肾功能异常的综述显示文摘肾功能异常是肝硬化的常见并发症,对临床表现和预后有着极为重要的影响。肝硬化患者易出现急性肾损伤(AKI);肝肾综合征(HRS)则是肾功能异常的一种特殊类型。肾前性AKI、肝肾综合征型AKI(HRS-AKI,以往称为1型)和急性肾小管坏死(ATN)是肝硬化中AKI最常见的类型。由于治疗策略不同,准确区分这些AKI类型是必要的。血浆容量扩张治疗对肾前性AKI有较好的效果,但HRS-AKI和ATN病死率较高,需要不同的治疗措施。最近,一些诊断标准(如以2.5mg/dL为界值的血肌酐水平诊断HRS-AKI)已被摒弃,用以HRS-AKI及其他类型的AKI进行早期诊断和治疗的新的尿液标志物则成为了研究热点。本文从病理生理、诊断、治疗策略方面对HRS-AKI与其他类型AKI的临床差异进行了全面探讨。Theresa Bucsics Elisabeth Krones 2017Gastroenterology Report2017,5,2:2
5Dis-counts and rebates granted, to public payers for medicines in Eu-ropean countries显示文摘Vogler S Zimmermann N’Habl C Piessnegger J Bucsics A 2012Southern Med Review2012,5,1:1
6Methylethers of cinchona alkaloids in Pt-catalyzed hydrogenation of methyl benzoylformate and pyruvaldehyde dimethyl acetal Part 2: Effect of stereochemical factors on the enantioselectivity 显示文摘Baldzsik K Bucsic I Cserenyi S 2008Journal of Molecular Catalysis A:Chemical2008,285,12:1
7Methylethers of cinchona alkaloids in Pt-catalyzed hydrogenation of ethyl pyruvate and ketopantolactone:Effect of stereochemical factors on the enantioselectivity 显示文摘Balazsik K Bucsic I Cserenyi S 2008Journal of Molecular Catalysis A: Chemical2008,280,12:1
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