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| 1 | Clinical analysis of intracranial germinoma's craniospinal irradiation using helical tomotherapy显示文摘Objective: To evaluate the short-term clinical outcomes of intracranial germinoma patients treated with craniospinal irradiation(CSI) using helical tomotherapy(HT) system in our center. Methods: Twenty-three patients who were treated with CSI in our center from January 2008 to July 2012 were collected, with an average age of 20. All of the patients' CSI used the HT system. The total doses were 27-36 Gy/15-20 F(1.5-2 Gy per fraction), and total local doses were 46-60 Gy/30-50 F(5 fractions per week). All female patients for CSI were treated with left-right parallel-opposed field irradiation to protect their ovarian functions. Median follow-up time was 30.9 months(range, 5-67 months). The SPSS19.0 software was used, and the overall survival(OS) was calculated using the Kaplan-Meier method.Results: Among 17 patients with assessable tumors, 9 cases(52.9%) were CR, 7 cases(41.2%) were PR, and 1 case(5.9%) was SD. Hematological toxicity was the severest side-effect occurred in the procedure of CSI. The level 1-4 acute leukopenia were 8.7%, 30.4%, 34.8% and 21.7% and the level 1-4 acute thrombopenia were 8.7%, 30.4%, 21.7% and 8.7%, respectively.Conclusions: For primary intracranial germinomas, HT can be used to implement CSI for simplifying radiotherapy procedures, improving radiotherapy accuracy, enhancing protection of peripheral organs at risk(ORA) and guaranteeing therapeutic effects. With the acceptable acute and long-term toxicity, CSI using HT in intracranial germinoma patients can be a safe and alternative mode. | Baolin Qu Lei Du Yurong Huang Wei Yu Boning Cai Shouping Xu Lin Ma | 2014 | Chinese Journal of Cancer Research2014，26，3： | 14 |
| 2 | Artemisinin derivatives inhibit epithelial ovarian cancer cells via autophagy-mediated cell cycle arrest显示文摘Epithelial ovarian cancer (EOC)is the most fatal gynecologic malignancy due to its late diagnosis and lack of curative therapy.The antimalaria compound artemisinin and its derivatives,such as artesunate (ART)and dihydroartemisinin (DHA),have proven to be potent anticancer drugs and act through various anticancer mechanisms.To identify novel targets of artemisinin derivatives in EOC cells,we investigated the effects of ART and DHA on SKOV3 and primary EOC cell growth via CCK-8 assay.Both ART and DHA inhibited EOC cell growth.A cell cycle distribution analysis showed that ART and DHA caused G2/M cell cycle arrest.Moreover,ART and DHA induced autophagy in EOC cells,whereas autophagy inhibitors reversed the cell growth inhibition and cell cycle arrest induced by ART and DHA.Western blot analysis showed that ART and DHA also suppressed the cell cycle-related NF-κB-signaling pathway in EOC cells.These data suggest that artemisinin derivatives induce autophagy,block the cell cycle,and inhibit cell growth in EOC cells.Our research provides new targets for artemisinin derivatives for EOC treatment. | Boning Li Shixia Bu Junyan Sun Ying Guo Dongmei Lai | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 11 |
| 3 | A RHOse by any other name:a comparative analysis of animal and plant Rho GTPases显示文摘Rho GTPases 是作为许多的关键管理者扮演细胞的进程的分子的开关,包括房间运动,形态发生,主机防卫,房间部门和基因表示。Rho GTPases 在所有真核细胞的王国被发现。植物缺乏清楚的相当或相同的事物到在酵母和动物发现的常规 Rho GTPases;相反,他们随着时间的过去开发了一个唯一的亚科, ROP,是也知道皇家装甲兵。象 ROP 一样蛋白质的起源看起来先于陆地植物的外观。这评论试图讨论 ROP/RAC 的进化并且比较植物 ROP 和动物 Rho GTPases,集中于 GTPases 和他们的下游的受动器的规定的类似和差别。 | Tore Brembu Per Winge Atle Magnar Bones Zhenbiao Yang | 2006 | Cell Research2006，16，5： | 7 |
| 4 | Perovskite light-emitting/detecting bifunctional fibres for wearable LiFi communication显示文摘Light fidelity(LiFi),which is emerging as a compelling technology paradigm shifting the common means of highcapacity wireless communication technologies,requires wearable and full-duplex compact design because of its great significance in smart wearables as well as the‘Internet of Things’.However,the construction of the key component of wearable full-duplex LiFi,light-emitting/detecting bifunctional fibres,is still challenging because of the conflicting process between carrier separation and recombination,as well as the highly dynamic film-forming process.Here,we demonstrate light-emitting/detecting bifunctional fibres enabled by perovskite QDs with hybrid components.The hybrid perovskite inks endow fibres with super-smooth QD films.This,combined with the small exciton binding energy and high carrier mobility of perovskite QDs,enables successful integration of electroluminescence and photodetection into monofilaments.The bifunctional fibres possess the narrowest electroluminescence full width at half maximum of ~19 nm and,more importantly,the capability for simultaneously transmitting and receiving information.The successful fabrication of narrow emission full-duplex LiFi fibres paves the way for the fabrication and integration of low crosstalk interoperable smart wearables. | Qingsong Shan Changting Wei Yan Jiang Jizhong Song Yousheng Zou Leimeng Xu Tao Fang Tiantian Wang Yuhui Dong Jiaxin Liu Boning Han Fengjuan Zhang Jiawei Chen Yongjin Wang Haibo Zeng | 2020 | Light(Science & Applications)2020，9，1： | 7 |
| 5 | 硒对T—2毒素所致大鼠软骨基质代谢的作用显示文摘用T—2毒素和不同硒含量的饲料喂养大鼠,观察软骨胶原和蛋白多糖组分的含量.结果表明:T—2毒素组各指标均低于对照组,尤以胶原和蛋白多糖中的硫酸基下降明显(P<0.01或<0.05),而三个加硒组各指标有不同程度的回升,接近或高于对照组,胶原和硫酸基含量随饲料用水平的增加而递增。提示T—2毒素对软骨组织具有毒性作用,影响基质中羟脯氨酸和蛋白多糖的合成,硒能够部分或全部拮抗T—2毒素的作用。 | Mo Xiaoyan et al(Institute of Endemic Bone Disease,Xi’an Medtical University) | 1994 | 中国地方病学杂志1994，13，2： | 6 |
| 6 | Application of Wavelet Transform Modulus Maxima in Raman Distributed Temperature Sensors显示文摘我们建议了并且示威小浪变换模量降噪方法减少的最大值(WTMM ) 温度错误。在这个计划,作文规模被 WTMM 振幅变化在 30 摯汵瑡潩 ? 整档楮畱与分解规模的生长简单地决定吗? | Zongliang WANG Jun CHANG Sasa ZHANG Sha LUO Cuanwu JIA Boning SUN Shuo JIANG Yongning LIU Xiaohui LIU Guangping LV Zhi LIU | 2014 | Photonic Sensors2014，4，2： | 5 |
| 7 | Consensus on clinical management of tumor-induced osteomalacia显示文摘Tumor-induced osteomalacia(TIO)is a rare paraneoplastic syndrome caused by excessive fibroblast growth factor 23(FGF23)production by a tumor,which often arises from a mesenchymal origin.[1-3]Most clinical symptoms of TIO are the consequences of prolonged FGF23-mediated hypophosphatemia as muscle weakness,bone pain,impaired mobility,and fractures.[4]Clinical diagnosis and management of TIO are challenging because knowledge about this condition is still restricted to a few specialized centers,leading to delay in diagnosis and appropriate treatment.The scope of the present consensus is to provide up-to-date guidance on the assessment and treatment of TIO. | Yan Jiang Xiang Li Li Huo Yong Liu Wei Lyu Lian Zhou Wei Yu Huan-Wen Wu Xiao-Ping Xing Mei Li Ou Wang Yue Chi Rui-Zhi Jiajue Yu Pei Jian-Min Liu Jian-Ming Ba Qiao Zhang Zhi-Feng Sheng Zhen-Lin Zhang Jia-Jun Zhao Salvatore Minisola Wei-Bo Xia on behalf of Chinese Society of Osteoporosis and Bone Mineral Research and Chinese Society of Endocrinology | 2021 | Chinese Medical Journal2021，，11： | 3 |
| 8 | A Method for Eliminating the Impact of Microwave Sweeper Power Fluctuation in BOTDA System显示文摘在 BOTDA 系统的微波 sweeper 电源变化的影响理论上被分析了并且试验性地测试了。并且把探查波浪电源的即时获得与一个新算法作比较为消除这影响认识到探查波浪电源正规化的一个新奇方法被建议。建议方法的原则理论上被描述。并且在我们的新方法和常规方法之间的对比测试被执行。实验结果显示温度精确性有效地被改进从 ? | Shuo Jiang Jun Chang Sasa Zhang Zongliang Wang Sha Luo Boning Sun Xiaohui Liu Yongning Liu Junqiang Tian Chuanwu Jia | 2014 | Photonic Sensors2014，4，1： | 2 |
| 9 | A Four-Element Sensor Array Consisting of Asymmetric Distributed-Feedback Fiber Lasers显示文摘在根据他们的斜坡效率登上顺序安排四不对称的分布式反馈的纤维激光(DFB-FL ) 形成的一个传感器数组系统被建议。产量平坦能有效地用不对称的 DFB-FLs 的申请被改进。尽管它获得了最小的泵力量,最后元素几乎与其它一起有一样的产量。相对紧张噪音(RIN ) 和传感器数组的松驰摆动频率也被分析。某个 DFB-FL 的松驰摆动频率与它在数组的相对位置相关,这被发现。并且某个 DFB-FL 的 RIN 被另外的元素总是在数组影响,它不大概他们的安排是依赖的。 | Pengpeng WANG Jun CHANG Cunguang ZHU Boning SUN Guangping LV Sasa ZHANG Yanjie ZHAO Zhihui SUN Xiaolei ZHANG Gangding PENG | 2014 | Photonic Sensors2014，4，2： | 2 |
| 10 | 用于反射型LCoS技术的前投式光学系统设计显示文摘开发了一种用于反射式LCOS技术的新型投影光学系统,经改善的偏轴设计简化了工艺,降低了成本。本文将讨论基于该设计的系统的性能。 | Matthew Bone 刘舒曼 | 2001 | 现代显示2001，，3： | 2 |
| 11 | Sepsis, SIRS and CARS显示文摘 | Bone R C Sir Isaac Newton | 1996 | Crit Care Med1996，24，7： | 2 |
| 12 | Sir Isaac Newton, sepsis, SIRS, and CARS显示文摘 | Roger C. Bone | 1996 | Critical Care Medicine1996，，7： | 2 |
| 13 | Analysis and Improvement of SNR in FBG Sensing System显示文摘到噪音比率(SNR ) 的信号的改进有重要意思到察觉到系统的纤维布拉格栅栏(FBG ) 。噪音以及察觉到系统的 FBG 的信号变细的来源被分析。光回来损失(ORL ) 引起的光噪音是在系统的噪音的主要来源,这被发现,并且 coupler 是信号的变细的主要来源。在光纤的元素的 ORL 的原因(例如跳线开关电报,接头和纤维结束) 被介绍。另外,优化纤维的建议光察觉到网络被介绍以便改进 SNR。压制噪音的方法由 FBG 的纤维结束接口引起了,用匹配索引的液体包括,把以在这份报纸提及的方法的纤维辫子弄弯并且劈开是 8 湩敧 ? 楷桴的纤维接口的观点角度吗? | Delong KONG Jun CHANG Peijun GONG Yongning LIU Boning SUN Xiangzhi LIU Pengpeng WANG Zongliang WANG Weijie WANG Yan ZHANG | 2012 | Photonic Sensors2012，2，2： | 2 |
| 14 | Fracture of the ankle and distal part of the tibia显示文摘 | Greend RV Michelson JD Bone LB | 1996 | J Bone Joint Surg(Am)1996，78，： | 2 |
| 15 | Fast and compact dynamic data compression based on composite rigid body construction显示文摘3D dynamic datasets compression still poses two challenges. One is high time cost due to growing data and complex computation of compression algorithms. The other is low compression factor because of complex motions of dynamic scenes and unknown motion equations. In this paper, composite rigid body construction for fast and compact compression of 3D dynamic datasets is proposed to solve these two problems. It accelerates the compression with a fast rigid body decomposition based on disjoint union, and avoids serial searching, comparing and merging of the rigid body decomposition. To increase the compression factor,composite rigid body is introduced with consideration of motion consistency among rigid bodies at different time periods. The results of the experiments show that our algorithm compresses dynamic datasets quickly and achieves a high compression factor. | MA ZhiQiang WANG LiLi ZHANG BoNing KE Wei ZHAO QinPing | 2014 | Science China(Information Sciences)2014，57，11： | 2 |
| 16 | MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN显示文摘 | Boning Liu Xiang Wu Bin Liu Changli Wang Yunde Liu Qinghua Zhou Ke Xu | 2012 | BBA - Molecular Basis of Disease2012，，11： | 2 |
| 17 | Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation显示文摘 | Roger C Bone | 1996 | Critical Care Medicine1996，，： | 2 |
| 18 | A controlled clinical trial of high -dose methylprednisolone in the treatment of severe sepsis and septic shock显示文摘 | Bone R C Fisher C J Clemmer T P | 1987 | N Engl J Med1987，317，： | 2 |
| 19 | BIOLOGIC MECHANISMS OF THE PROTECTIVE ROLE OF LUTEIN AND ZEAXANTHIN IN THE EYE显示文摘 | Norman I. Krinsky John T. Landrum Richard A. Bone | 2003 | Annual Review of Nutrition2003，，： | 2 |
| 20 | Stable isotope labeling of nanomaterials for biosafety evaluation and drug development显示文摘Quantitative information,such as environmental migration,absorption,biodistribution,biotransformation,and elimination,is fundamental and essential for the nanosafety evaluations of nanomaterials.Due to the complexity of biological and environmental systems,it is challenging to develop quantitative approaches and tools that could characterize intrinsic behaviors of nanomaterials in the organisms.The isotopic tracers are ideal candidates to tune the physical properties of nanomaterials while preserving their chemical properties.In this review article,we summarized the stable isotope labeling methods of nanomaterials for evaluating their environmental and biological effects.The skeleton labeling protocols of carbon nanomaterials and metal/metal oxide nanoparticles were introduced.The advantages and disadvantages of stable isotope labeling were discussed in comparison with other quantitative methods for nanomaterials.The quantitative information of nanomaterials in environmental and biological systems was summarized along with the biosafety data.The benefits for drug development of nanomedicine were analyzed based on the targeting effects,persistent accumulation,and safety.Finally,the challenges and future perspectives of stable isotope labeling in nanoscience and nanotechnology were discussed. | Xue-Ling Chang Lingyun Chen Boning Liu Sheng-Tao Yang Haifang Wang Aoneng Cao Chunying Chen | 2022 | Chinese Chemical Letters2022，33，7： | 2 |
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