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| 1 | A novel biodegradable Mg-1Zn-0.5Sn alloy:Mechanical properties,corrosion behavior,biocompatibility,and antibacterial activity显示文摘To meet the growing demand for antibacterial implants for bone-implant-associated infection therapy and avoid the adverse effects of secondary surgery,a degradable platform with pH responsiveness and ion-associated antibacterial properties was constructed.A small amount of Sn added to Mg-1Zn alloy reduces the biocorrosion rate,which can be attributed to Sn participation in outer-layer film formation,significantly reducing the biocorrosion rate and hydrogen evolution rate after implantation in vivo.These Mg alloys,which are susceptible to degradation in the acidic bacterial microenvironment,degrade by releasing Mg,Zn and Sn,producing favorably alkaline and antibacterial conditions.Samples with the composition of Mg-1Zn-0.5Sn were found to be beneficial for promoting initial cell adhesion and proliferation,resulting in improved biocompatibility and biosafety.The biocompatibility of this alloy was confirmed by the healthy behavior of animals and the absence of acute or chronic toxicity in the liver,spleen,and kidneys.Our results demonstrate that Mg-1Zn-0.5Sn is safe for biological systems,enabling its efficacious use in biomedical applications. | Weikang Zhao Jingfeng Wang Jiang Weiyang Bo Qiao Yiyang Wang Yuling Li Dianming Jiang | 2020 | Journal of Magnesium and Alloys2020，8，2： | 3 |
| 2 | Improving in vitro and in vivo corrosion resistance and biocompatibility of Mg-1Zn-1Sn alloys by microalloying with Sr显示文摘Magnesium(Mg)and its alloys have attracted attention as potential biodegradable materials in orthopedics due to their mechanical and physical properties,which are compatible with those of human bone.However,the effect of the mismatch between the rapid material degradation and fracture healing caused by the adverse effect of hydrogen(H2),which is generated during degradation,on surrounding bone tissue has severely restricted the application of Mg and its alloys.Thus,the development of new Mg alloys to achieve ideal degradation rates,H2 evolution and mechanical properties is necessary.Herein,a novel Mg-1Zn-1Sn-xSr(x=0,0.2,0.4,and 0.6 wt%)quaternary alloy was developed,and the microstructure,mechanical properties,corrosion behavior and biocompatibility in vitro/vivo were investigated.The results demonstrated that a minor amount of strontium(Sr)(0.2 wt%)enhanced the corrosion resistance and mechanical properties of Mg-1Zn-1Sn alloy through grain refinement and second phase strengthening.Simultaneously,due to the high hydrogen overpotential of tin(Sn),the H2 release of the alloys was significantly reduced.Furthermore,Sr-containing Mg-1Zn-1Sn-based alloys significantly enhanced the viability,adhesion and spreading of MC3T3-E1 cells in vitro due to their unique biological activity and the ability to spontaneously form a network structure layer with micro/nanotopography.A low corrosion rate and improved biocompatibility were also maintained in a rat subcutaneous implantation model.However,excessive Sr(>0.2 wt%)led to a microgalvanic reaction and accelerated corrosion and H2 evolution.Considering the corrosion resistance,H2 evolution,mechanical properties and biocompatibility in vitro and in vivo,Mg-1Zn-1Sn-0.2Sr alloy has tremendous potential for clinical applications. | Yafeng Wen Qingshan Liu Jingfeng Wang Qiming Yang Weikang Zhao Bo Qiao Yuling Li Dianming Jiang | 2021 | Bioactive Materials2021，6，12： | 3 |
| 3 | Colour compound lenses for a portable fluorescence microscope显示文摘In this article,we demonstrated a handheld smartphone fluorescence microscope(HSFM)that integrates dualfunctional polymer lenses with a smartphone.The HSFM consists of a smartphone,a field-portable illumination source,and a dual-functional polymer lens that performs both optical imaging and filtering.Therefore,compared with the existing smartphone fluorescence microscope,the HSFM does not need any additional optical filters.Although fluorescence imaging has traditionally played an indispensable role in biomedical and clinical applications due to its high specificity and sensitivity for detecting cells,proteins,DNAs/RNAs,etc.,the bulky elements of conventional fluorescence microscopes make them inconvenient for use in point-of-care diagnosis.The HSFM demonstrated in this article solves this problem by providing a multifunctional,miniature,small-form-factor fluorescence module.This multifunctional fluorescence module can be seamlessly attached to any smartphone camera for both bright-field and fluorescence imaging at cellular-scale resolutions without the use of additional bulky lenses/filters;in fact,the HSFM achieves magnification and light filtration using a single lens.Cell and tissue observation,cell counting,plasmid transfection evaluation,and superoxide production analysis were performed using this device.Notably,this lens system has the unique capability of functioning with numerous smartphones,irrespective of the smartphone model and the camera technology housed within each device.As such,this HSFM has the potential to pave the way for realtime point-of-care diagnosis and opens up countless possibilities for personalized medicine. | Bo Dai Ziao Jiao Lulu Zheng Hunter Bachman Yongfeng Fu Xinjun Wan Yule Zhang Yu Huang Xiaodian Han Chenglong Zhao Tony Jun Huang Songlin Zhuang Dawei Zhang | 2019 | Light(Science & Applications)2019，8，1： | 3 |
| 4 | Chinese tomato yelIow Ieaf curl virus— a new species of geminivirus显示文摘 | Yule Liu Jianhe Cai Dongling Li Bixia Qin Bo Tian | 1998 | Science in China Series C: Life Sciences1998，，4： | 1 |
| 5 | Chinese tomato yelIow Ieaf curl virus— a new species of geminivirus显示文摘 | Yule Liu Jianhe Cai Dongling Li Bixia Qin Bo Tian | 1998 | Science in China Series C: Life Sciences1998，，4： | 1 |
| 6 | Dimensions estimation for cone-cylinder target based on sliding-type scatterers analysis显示文摘Scatterers often exhibit aspect or frequency dependence which affects the micro-Doppler shift in scattering response.For cone-cylinder targets, sliding-type scatterers which slide on the edge discontinuity with the change of the incident angle are the most dominant nonideal scattering models. A method is proposed to discriminate among the scatterers on the cone-cylinder target based on the deviation degree of micro-Doppler from sinusoid.By extracting the amplitude and initial phase, the micro-Doppler is estimated as sinusoid. Then the deviation degree is evaluated by the error between the extracted sinusoidal micro-Doppler and the actual micro-Doppler curve. Threshold for the classification is determined with the simulation data. After classification, the micro-Doppler features of sliding-type scatterers are exploited to estimate the target dimensions. The influence of parameters errors and noise on estimation of target dimensions is also illustrated with the simulation data. | Yuling Liu Xizhang Wei Bo Peng Yongshun Ling | 2017 | Journal of Systems Engineering and Electronics2017，28，1： | 1 |
| 7 | The investigation of DARC etch back in DRAM capacitor oxide mask opening显示文摘Opening the silicon oxide mask of a capacitor in dynamic random access memory is a critical process on a capacitive coupled plasma(CCP)etch tool.Three steps,dielectric anti-reflective coating(DARC)etch back,silicon oxide etch and strip,are contained.To acquire good performance,such as low leakage current and high capacitance,for further fabricating capacitors,we should firstly optimize DARC etch back.We developed some experiments,focusing on etch time and chemistry,to evalu-ate the profile of a silicon oxide mask,DARC remain and critical dimension.The result shows that etch back time should be con-trolled in the range from 50 to 60 s,based on the current equipment and condition.It will make B/T ratio higher than 70%mean-while resolve the DARC remain issue.We also found that CH_(2)F_(2) flow should be~15 sccm to avoid reversed CD trend and keep in-line CD. | Jianqiu Hou Zengwen Hu Kuowen Lai Yule Sun Bo Shao Chunyang Wang Xinran Liu Karson Liu | 2021 | Journal of Semiconductors2021，42，7： | 1 |
| 8 | Chinese tomato yelIow Ieaf curl virus— a new species of geminivirus显示文摘 | Yule Liu Jianhe Cai Dongling Li Bixia Qin Bo Tian | 1998 | Science in China Series C: Life Sciences1998，，4： | 1 |
| 9 | Hybrid algorithm based on particle swarm optimization and artificial fish swarm algorithm显示文摘 | Jiang Jingqing Bo Yuling Song Chuyi | 2012 | Lecture Notes in Computer Science2012，7367，： | 1 |
| 10 | Chinese tomato yelIow Ieaf curl virus— a new species of geminivirus显示文摘 | Yule Liu Jianhe Cai Dongling Li Bixia Qin Bo Tian | 1998 | Science in China Series C: Life Sciences1998，，4： | 1 |
| 11 | Chinese tomato yelIow Ieaf curl virus— a new species of geminivirus显示文摘 | Yule Liu Jianhe Cai Dongling Li Bixia Qin Bo Tian | 1998 | Science in China Series C: Life Sciences1998，，4： | 1 |
| 12 | Construction of superhydrophobic directly Z-scheme bismuth oxybromide/silver phosphate fabric surface with UV shielding and enhanced visible light absorption activity显示文摘Various forms of pollutants discharged from industrial and life;how to treat the opposite water-soluble pollutants at the same time is a challenge.Here,a superhydrophobic BiOBr/Ag3PO4 fabric(SH fabric)bulk material was prepared aiming at the diversity of pollutants.Water(WCA=160°)and oil contaminants(spread)have different wetting behavior on fabric surfaces.The high recovery efficiency for oil pollutants was achieved by using the selective oil removal property of the SH fabric.Meanwhile,the pollutants in the aqueous phase were removed by photocatalyst after oil/water separation.Mechanism analysis demonstrated that the direct Z-type heterojunction formed between BiOBr(EVB=1.66 eV;ECB=-1.08 eV)and Ag3PO4(EVB=3.03 eV;ECB=0.6 eV).It is worth noting that the SH fabric exhibited good mechanical stability and UV shielding performance,which have potential application in environmental control. | GE Bo ZHANG YuLing ZHANG TingXiao REN GuiNa LI WenZhi ZHAO Hui | 2021 | Science China(Technological Sciences)2021，64，4： | 1 |
| 13 | An old story with new insight into the structural transformation and radical production of micron-scale zero-valent iron on successive reactivities显示文摘It is generally recognized that the formation and accumulation of iron oxides on the surface of zero-valent iron(Fe^(0))resulting in significant decrease of contaminant degradation rates during the long-term reactions.However,in this study,we found that the removal efficiencies of p-nitrophenol(PNP)by micro zero-valent iron(mFe^(0))could maintain at the satisfactory level in the process of continuous reactions(20 cycles).The removal rate constant(0.1779 min^(-1))of the 5th cycle was 6.74 times higher than that of the 1streaction(0.0264 min^(-1)),even the 20th cycle(0.0371 min^(-1))was higher than that of the 1st reaction.Interestingly,almost no dissolved iron was detected in the solution,and the total iron concentrations decreased dramatically with the process of continuous reactions.The results of scanning electron microscope and energy dispersive spectrometry(SEM-EDS)and X-ray diffraction(XRD)revealed that the structure and composition of corrosion products change from amorphous to highly crystal with the increase of the number of cycles.The corrosion products were mainly magnetite(Fe_(3)O_(4))and a small part of maghemite(γ-Fe_(2)O_(3)),which were in the form of micro sphe res on the surface of mFe^(0).The formation of surface oxidation shell hindered the release of Fe^(2+).X-ray photoelectron spectroscopy(XPS)results illustrated that partial Fe3O_(4) could be converted into y-Fe_(2)O_(3).Electrochemical analysis proved that the electron transfer rate of mFe^(0) increased with the formation of the oxides shell.However,the consumption of iron core and thicker oxide film weakened the electron transfer rate.Besides,the quenching experiments indicated that the reaction activity of mFe^(0) could be enhanced with the addition of scavengers.This study deepened the understanding of the structural transformation and radical production of mFe^(0) in continuous reactions. | Xinhao Wang Xueting Pu Yue Yuan Yunjie Xiang Yuling Zhang Zhaokun Xiong Gang Yao Bo Lai | 2020 | Chinese Chemical Letters2020，31，10： | 0 |
| 14 | Genetic Architecture of Childhood Kidney and Urological Diseases in China显示文摘Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to 2020.Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features.The genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in China.Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were identified.Ten distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 patients.The diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions.We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed.Our data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease. | Ye Fang Hua Shi Tianchao Xiang Jiaojiao Liu Jialu Liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin Li Li Sun Yunli Bi Xiang Wang Yanyan Qian Bingbing Wu Huijun Wang Wenhao Zhou Duan Ma Jianhua Mao Xiaoyun Jiang Shuzhen Sun Ying Shen Xiaorong Liu Aihua Zhang Xiaowen Wang Wenyan Huang Qiu Li Mo Wang Xiaojie Gao Yubin Wu Fang Deng Ruifeng Zhang Cuihua Liu Li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao Xuemei Liu Mei Han Lijun Zhao Yuling Liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma Liping Zhao Zhengkun Xia Biao Lu Yulong Wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua He Huifeng Zhang Bo Zhao Xiaohua LI Feiyan Wang Yufeng Li Hongtao Zhu Xinhui Luo Jinghai Li Jia Rao Hong Xu | 2021 | Phenomics2021，1，3： | 0 |
| 15 | A new member of Sphenopsida,Neolobatannularia gen. nov. from Late Triassic of western Liaoning,China显示文摘A new genus Neolobatannularia Sun et Li gen. nov. with the type species Neolobatannularia liaoningensis Sun et Li sp. nov. from the Upper Triassic Yangcaogou Formation of Beipiao, Liaoning, China, is described in this paper. The new taxon is attributed to Equisetales of Sphenopsida based on its branch with internodes, node and leaves borne in whorls on nodes. It is a new member of the Mesozoic Sphenopsida. Although the new taxon shares some morphological characters with the genus Lobatannularia Kawasaki, a genus widely distributed in the Permian Cathaysia flora in East Asia, and the genus Lobatannulariopsis Yang from the Late Triassic of southwestern China, its unique branching pattern is markedly distinguished from the two known genera. Some Triassic known species of Lobatannularia may belong to the present new genus Neolobatannularia. | WANG Junyou LI Tao LIU Zhiping GUO Bin KANG Ai NA Yuling LI Yunfeng WANG Hongshan BO Junchen SUN Chunlin | 2019 | Global Geology2019，22，1： | 0 |
| 16 | Expression of human hepatitis C virus core antigen in tobacco plants by tobacco mosaic virus-based vector system显示文摘Tobacco mosaic virus (TMV) has the potential to highly express foreign gene. A novel TMV-based in trans expression system was constructed. A TMV mutant TSHc had its coat protein replaced with hepatitis C vir黶 (HCV) core antigen gene. Anotherr TMV mutant TSBD was repli-case-defective. Coinfection of the two mutants could cause systemic infection in tobacco plants by in trans complementation of their functions. TSHc could effectively replicate and assemble to viral particles, which were a little longer than that of wild-type TMV. HCV core antigen was expressed in whole tobacco plants. A similar expression level of HCV core antigen was detected on serial passages, which suggested that this viral expression system be stable. | HAN Aidong LIU Yule XIAO Li KANG Liangyi ZHANG Yuman LI Dongtian TIAN Bo | 2000 | Chinese Science Bulletin2000，45，1： | 0 |
| 17 | A green cross-linking method for the preparation of renewable threedimensional graphene sponges for efficient adsorption of Congo red dye显示文摘Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high preparation costs,low yields,environmental pollution during synthesis,and challenges in regenerating the adsorbent.This study proposes a novel approach to address these limitations by developing nitrogen-doped three-dimensional(3D)polyvinyl alcohol(PVA)crosslinked graphene sponges(N-PGA)using a cross-linking method with ammonium carbonate.This method offers a relatively mild,environmentally friendly approach.Ammonium carbonate serves as both a reducing and modifying agent,facilitating the formation of the intrinsic structure of N-PGA and acting as a nitrogen source.Meanwhile,PVA is utilized as the cross-linking agent.The results demonstrate that N-PGA exhibits a favorable internal 3D hierarchical porous structure and possesses robust mechanical properties.The measured specific surface area(BET)of N-PGA was as high as406.538 m^(2)·g^(-1),which was favorable for its efficient adsorption of Congo red(CR)dye molecules.At an initial concentration of 50 mg·L^(-1),N-PGA achieved an impressive removal rate of 89.6%and an adsorption capacity of 112 mg·g^(-1)for CR dye.Furthermore,it retained 79%of its initial adsorption capacity after 10 cycles,demonstrating excellent regeneration performance.In summary,the synthesized N-PGA displays remarkable efficacy in the adsorption of CR dye in wastewater,opening up new possibilities for utilizing 3D porous graphene nanomaterials as efficient adsorbents in wastewater treatment. | Zhuang Liu Bo Gao Haoyuan Han Yuling Li Haiyang Fu Donghui Wei | 2024 | Chinese Journal of Chemical Engineering2024，66，2： | 0 |
| 18 | Activity of the truncated promoter of pollen-specific G9 gene of cotton and the transgenic recessive nuclei-sterile tobacco显示文摘A 557 bp fragment from the translation initiation site of the G9 gene expressed in maturing pollens of cotton was isolated from genomic DNA of upland cotton (Gossypium hirsutum L.) cv. “Zhongkang 17”, and two expression vectors for plant transformation were constructed via fusing this fragment with β-glucuronidase gene (Gus) and cytotoxin gene Barnase. The promoter activity of this fragment was demonstrated via transient expression of Gus gene in cotton and by the integrated expression of Barnase gene in tobacco. This promoter can initiate the expression of exogenous gene specifically and efficiently in plant pollen. The transgenic tobacco plant containing G9-Barnase fusion gene showed the characteristics of recessive nuclei-sterility. | MA Hong, WANG Huanyu, LIU Yule, YANG Huaiyi and TIAN Bo(Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China) | 2002 | Progress in Natural Science:Materials International2002，12，3： | 0 |
| 19 | An improved Hummers method to synthesize graphene oxide using much less concentrated sulfuric acid显示文摘The production of graphene oxide with less acid is beneficial to reduce the costs and lower the impact on the environment,but it is still a great challenge.In this work,a relatively simple,safe method for synthesizing graphene oxide with much less acid(decrease∼40%)is proposed.With assistance of the heat absorbed from environment and reaction system,the temperature of reaction system of low acid can be well controlled.More interestingly,the graphite can be completely oxidized into graphite oxide by using much less acid,with lowering the production of high-concentration aqueous waste acid(>1 mol/L,decrease∼40%).A series of characterizations show that the prepared graphene oxide has similar yield and functional groups compared with that of using the conventional method.This work provides a safe and environmentally friendly choice for the large-scale production of graphene oxide and its derivative materials. | Yanbin Zhu Gang Kong Yuling Pan Lian Liu Bo Yang Shuanghong Zhang Delin Lai Chunshan Che | 2022 | Chinese Chemical Letters2022，33，10： | 0 |
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