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| 1 | Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples显示文摘瞄准:比较胰腺的腺癌织物标本的基因表示侧面,胰腺的人和腺癌和白血病房间线和正常的胰取样以便区分差别的冒号表示了基因并且在内视镜的指导超声的好针渴望( 指导EUS 的 FNA )由量的即时 RT-PCR ( RT-QPCR )验证基因的一个子集的微分表示标本。方法:包含 1176 基因的商业地奉献的癌症 cDNA 宏数组(地图集人癌症 1.2 ) 被使用。不同统计途径(层次聚类的、主要部件分析(PCA ) 和 SAM ) 被用来分析表示数据。RT-QPCR 和免疫组织化学的研究被用于结果的确认。结果:RT-QPCR 验证了 LCN2 的增加的表示(lipocalin 2 ) 并且第一次在恶意的胰的小块地(织物类型 plasminogen 使活跃之物或 tPA ) 同样与正常相比胰。Immunohistochemical 分析证实了在癌入侵的管的上皮细胞局部性的 LCN2 蛋白质的增加的表示。在与胰腺的腺癌从病人通过指导 EUS 的 FNA 获得的 12 件样品的小块地和 LCN2 抄本的分析与在正常纸巾发现的那些比较显示出显著地增加的表示层次,显示高质量的 RNA 的足够的数量能与这种技术被获得。结论:表示介绍是一个有用方法识别简历标记和潜在的目标基因。在胰腺的癌症的指导 EUS 的 FNA 样品的分子的分析为胰腺的腺癌的诊断作为珍贵策略出现。 | Henrik Laurell Michèle Bouisson Philippe Berthelémy Philippe Rochaix Sébastien Déjean Philippe Besse Christiana Susini Lucien Pradayrol Nicole Vaysse Louis Buscail | 2006 | World Journal of Gastroenterology2006，12，21： | 5 |
| 2 | Laparoscopically assisted myomectomy: a report of a new technigue in 57 cases 显示文摘 | Nezhat C Nezhat F Bess D | 1994 | Int J Fertil Menopausal Stud1994，39，： | 1 |
| 3 | Impact of K-ras in standardtreatment of non-small cell lung cancer(NSCLC)patients in2009:prognostic and predictive value显示文摘 | Planchard D Loriot Y Besse B | 2009 | Bull Cancer2009，96，： | 1 |
| 4 | Public Health Literacy Defined 显示文摘 | Freedman D A Bess K D Tucker H A | 2009 | American Journal of Preven- tive Medicine2009，36，5： | 1 |
| 5 | Regulation of opioid binding sites in the superficial dorsal horn of the rat spinal cord following loose ligation of t he sciatic nerve: comparison with sciatic nerve section and lumbar dorsal rhizot omy显示文摘 | Lombard MC Perrot S | 1992 | Neuroscience1992，50，： | 1 |
| 6 | In situ polymerization of aniline sulfonic acid derivatives into LDH inteflamel- lar space probed by ESR and electrochemical studies显示文摘 | E1 M M Marc D Besse J P | 2005 | Chem Mater2005，17，2： | 1 |
| 7 | Ultrastruetural localization of interferoninducible double-stranded RNA-actived enzymes in human cells显示文摘 | Besse S Rebouillat D Marie I | 1998 | Exp Cell Res1998，239，2： | 1 |
| 8 | Effects of vitamin D and calcium supplementation on pancreatic cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus ( CaDDM ) randomized controlled triM显示文摘 | Joanna M Bess D H Hu F B | 2011 | Am J Clin Nutr2011，94，2： | 1 |
| 9 | Pain and disabil-ity determine treatment modality for older patients with adultscoliosis, while deformity guides treatment for younger pa-tients显示文摘 | Bess S Boachie-Adjei 0 Burton D | 2009 | Spine2009，34，20： | 1 |
| 10 | Mitogen-activated protein kinase activation in lung adenocarcinoma:a comparative study between ever smokers and never smokers显示文摘 | Mountzios G Planchard D Besse B | | 0，，： | 1 |
| 11 | Impact of KRAS in standard treatment of non-small cell lung cancer (NSCLC) patients in 2009: prognostic and predictive value显示文摘 | Planchard D Loriot Y Besse B | 2009 | Bull Cancer2009，96，： | 1 |
| 12 | Impact of KRAS in standard treatment of non-smal cell lung cancer (NSCLC) patients in 2009:prognostic and predictive value显示文摘 | Planchard D Loriot Y Besse B | | 0，，： | 1 |
| 13 | Effect of antioxi-dant inclusion and oil quality on broiler performance,meat quality,and lipid oxidation显示文摘 | Tavárez M A Boler D D Bess K N | | 0，，04： | 1 |
| 14 | Design, Synthesis, and Pharmacological Characterization of 4- 显示文摘 | MARCIAN E D DIANE M R BESS W | 2000 | J Med Chem2000，43，17： | 1 |
| 15 | An Efficient Isolation Procedure of Ca-tolerant Ventricular Myocytes from Ferret Heart for Applications in Electrophysiological Studies显示文摘 | Bouron A Potreau D Besse C | 1990 | Biol Cell1990，70，3： | 1 |
| 16 | MicroRNA profiles in osteosarcoma as a predictive tool for ifosfamide response显示文摘 | Gougelet A Pissaloux D Besse A | | 0，，03： | 1 |
| 17 | Estimates of optimal vitamin D status显示文摘 | Bess D H Robert P H Michael F H | 2005 | Osteoporos Int2005，16，7： | 1 |
| 18 | Effect of antioxidant inclusion and oil quality on broiler performance,meat quality,and lipid oxidation 显示文摘 | Tavdrez M A Boler D D Bess K N et a/ | 2011 | Poult Sci2011，90，92： | 1 |
| 19 | Plasma membrane is the site of productive HIV-I particle assembly显示文摘 | Jouvenet N Neil S J D Bess C | 2006 | PLoS Bioi2006，4，： | 1 |
| 20 | TCTP protects from apoptotie cell death by antagonizing bax func- tibn显示文摘 | Susini L Besse S Duflaut D | 2008 | Cell Death Differ2008，15，8： | 1 |
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