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| 1 | Resective surgery for liver tumor: a multivariate analysis of causes and risk factors linked to postoperative complications显示文摘BACKGROUND: In spite of accurate selection of patients eligible for resection, and although advances in surgical techniques and perioperative management have greatly contributed to reducing the rate of perioperative deaths, stress must be placed on reducing the postoperative complication rates reported to be still as high as 50%. This study was designed to analyze the causes and foreseeable risk factors linked to postoperative morbidity on the grounds of data derived from a single-center surgical population. METHODS: From September 1989 to March 2005, 287 consecutive patients, affected either with HCC or liver metastasis, had liver resection at our department. Among the HCC series we recorded 98 patients (73.2%) in Child- Pugh class A, 32 (23.8%) in class B and 4 in class C (3%). In 104 colorectal metastases, 71% were due to colon cancer, 25% rectal, 3% sigmoid, and 1% anorectal. In 49 non-colorectal metastases, 22.4% were derived from breast cancer, 63.2% gastrointestinal tumors (excluding colon) and 14.4% other cancers. We performed 80 wedge resections, 77 bisegmentectomies and/or left lobectomies, 74 segmentectomies, 22 major hepatectomies, 20 left hepatectomies, and 14 trisegmentectomies. RESULTS: The in-hospital mortality rate in this series was 4.5%, and the morbidity rate was 47.7%, because of pleural effusion (30%), hepatic abscess (25%), hepatic insufficiency (19%), ascites (10%), hemoperitoneum (10%), or biliary fistula (6%). The variables associated with the technical aspects of the surgical procedure thatwere responsible for the complications were: a Pringle maneuver length more than 20 minutes (P=0.001); the type of liver resection procedure, including major hepatectomy (P=0.02), left hepatectomy (P=0.04), trisegmentectomy (P=0.04), bisegmentectomy and/or left lobectomy (P=0,04); and a blood transfusion of more than 600 ml (P=0.04). CONCLUSION: The evaluation of causes and foreseeable risk factors linked to postoperative morbidity during the planning of surgical treatment should play the same role as other factors weighed in the selection of patients eligible for liver resection. | Enrico Benzoni Dario Lorenzin Umberto Baccarani Gian Luigi Adani Alessandro Favero Alessandro Cojutti Fabrizio Bresadola Alessandro Uzzau | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，4： | 17 |
| 2 | An empirical investigation of continuous-time models for equity returns 显示文摘 | ANDERSEN T BENZONI L LUND J | 2002 | Journal of Finance2002，57，3： | 1 |
| 3 | The role of pancreatic leakage on rising of postoperative complications following pancreatic surgery显示文摘 | Benzoni E Saccomano E Zompicchiatti A | 2008 | J Surg Res2008，149，2： | 1 |
| 4 | The role of pancreatic leakage on rising of postoperative complications following pancreatic surgery显示文摘 | Benzoni E Saccomano E Zompicchiatti A | | 0，，02： | 1 |
| 5 | The role of pancreatic leakage on rising of postoperative complications follow- ing pancreatic surgery显示文摘 | Benzoni E Saccomano E Zompicchiatti A | 2008 | J Surg Res2008，149，2： | 1 |
| 6 | Seismic response of linked marginal wharf segments显示文摘 | BENZONI G PRIESTLEY M J N | 2003 | Journal of Earthquake Engineering2003，7，4： | 1 |
| 7 | An empirical investigation of continuous time equity return models显示文摘 | Benzoni L Lund J | 2002 | Journal of Finance2002，57，3： | 1 |
| 8 | The role of pancreatic leakage on rising of postoperative complications following pancreatic surgery 显示文摘 | Benzoni E Saccomano E Zompicchiatti A | 2008 | J Surg Res2008，149，2： | 1 |
| 9 | Challenges of new generation seismic testing facilities显示文摘 | Benzoni G | 2001 | Experimental Techniques2001，25，2： | 1 |
| 10 | Genetic and morphometric evidence for unresolved species boundaries in the coral ge- nus Psammocora (Cnidaria; Scleractinia) 显示文摘 | Stefani F Benzoni F Pichon M | 2008 | Hydrobiologia2008，596，： | 1 |
| 11 | laver resection for HCC: analysis of causes and risk factors linked to postoperative com- plications显示文摘 | Benzoni E Molaro R | 2007 | Hepatogastroenterology2007，54，73： | 1 |
| 12 | Influence of in vitro exposure to mycotoxin zearalenone and its derivatives on swine sperm quality显示文摘 | Benzoni E Minervini F Giannoccaro A | 2008 | Reprod Toxicol2008，25，4： | 1 |
| 13 | Genetic and morphometric evidence for unresolved species boundaries in the coral genus Psammocora (Cnidaria;Scleractinia)显示文摘 | Stefani F Benzoni F Pichon M | 2008 | Hydrobiologia2008，596，： | 1 |
| 14 | Liver resective surgery: a multivariate analysis of postoperative outcome and complication显示文摘 | Benzoni E Cojutti A Lorenzin D | 2007 | Langenbecks Arch Surg2007，392，1： | 1 |
| 15 | Estimating jump-diffusions for equity returns显示文摘 | Andersen T G Benzoni L Lund J | | 0，，： | 1 |
| 16 | The role of pancreatic leakage on rising of postoperative complications following pancreatic sugery显示文摘 | Benzoni E Saccomano E Zompicchiatti A | 2008 | J Surg Res2008，149，2： | 1 |
| 17 | Liver resective surgery: a muhivariate analysis of postoperative outcome and complication 显示文摘 | Benzoni E Cojutti A Lorenzin D | 2007 | Langenbecks Arch Surg2007，392，1： | 1 |
| 18 | The role of pancreatic leakage on rising ofpostoperative complications following pancreaticsurgery显示文摘 | Benzoni E Saccomano E Zompicchiatti A | 2008 | J Surg Res2008，，： | 1 |
| 19 | Instrumental clinical restaging,pathological evaluation,and tumor regression grading:How to assess the response to neoadjuvant chemoradiotherapy for rectal cancer显示文摘 | Benzoni E Terrosu G Intersimone D | 2007 | Int J Colorectal Dis2007，22，1： | 1 |
| 20 | An Empirical Investigation of Continuous Time Models for Equity Returns 显示文摘 | Andersen T G Benzoni L Lund J | 2002 | Journal of Finance2002，57，3： | 1 |
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