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| 1 | Defining response to radiotherapy in rectal cancer using magnetic resonance imaging and histopathological scales显示文摘AIM To define good and poor regression using pathology and magnetic resonance imaging(MRI) regression scales after neo-adjuvant chemotherapy for rectal cancer.METHODS A systematic review was performed on all studies up to December 2015, without language restriction, t h a t w e r e i d e n t i f i e d f r o m M E D L I N E, C o c h r a n e Controlled Trials Register(1960-2015), and EMBASE(1991-2015). Searches were performed of article bibliographies and conference abstracts. MeS H and text words used included 'tumour regression', 'mr TRG', 'poor response' and 'colorectal cancers'. Clinical studies using either MRI or histopathological tumour regression grade(TRG) scales to define good and poor responders were included in relation to outcomes [local recurrence(LR), distant recurrence(DR), disease-free survival(DFS), and overall survival(OS)]. There was no age restriction or stage of cancer restriction for patient inclusion. Data were extracted by two authors working independently and using pre-defined outcome measures.RESULTS Quantitative data(prevalence) were extracted and analysed according to meta-analytical techniques using comprehensive meta-analysis. Qualitative data(LR, DR, DFS and OS) were presented as ranges. The overall proportion of poor responders after neo-adjuvant chemoradiotherapy(CRT) was 37.7%(95%CI: 30.1-45.8). There were 19 different reported histopathological scales and one MRI regression scale(mrT RG). Clinical studies used nine and six histopathological scales for poor and good responders, respectively. All studies using MRI to define good and poor response used one scale. The most common histopathological definition for good response was the Mandard grades 1 and 2 or Dworak grades 3 and 4; Mandard 3, 4 and 5 and Dworak 0, 1 and 2 were used for poor response. For histopathological grades, the 5-year outcomes for poor responders were LR 3.4%-4.3%, DR 14.3%-20.3%, DFS 61.7%-68.1% and OS 60.7-69.1. Good pathological response 5-year outcomes were LR 0%-1.8%, DR 0%-11.6%, DFS 78.4%-86.7%, and OS 77.4%-88.2%. A poor response on MRI(mr TRG 4,5) resulted in 5-year LR 4%-29%, DR 9%, DFS 31%-59% and OS 27%-68%. The 5-year outcomes with a good response on MRI(mrT RG 1,2 and 3) were LR 1%-14%, DR 3%, DFS 64%-83% and OS 72%-90%.CONCLUSION For histopathology regression assessment, Mandard 1, 2/Dworak 3, 4 should be used for good response and Mandard 3, 4, 5/Dworak 0, 1, 2 for poor response. MRI indicates good and poor response by mr TRG1-3 and mrT RG4-5, respectively. | Muhammed RS Siddiqui Jemma Bhoday Nicholas J Battersby Manish Chand Nicholas P West Al-Mutaz Abulafi Paris P Tekkis Gina Brown | 2016 | World Journal of Gastroenterology2016，22，37： | 6 |
| 2 | “新金砖”南非显示文摘当下最热门的经济词汇是什么?当然是BRICS(金砖国家)。 | John Battersby Yingni Lu 侯隽 | 2011 | 中国经济周刊2011，，15： | 2 |
| 3 | Diagnosis, incidence, and outcomes of suspected typhlitis in oncology patients—experience in a tertiary pediatric surgical center in the United Kingdom显示文摘 | Dhanya Mullassery Abdulgader Bader Anna J. Battersby Zeenat Mohammad Emma Louise L. Jones Chetan Parmar Roger Scott Barry L. Pizer Colin T. Baillie | 2009 | Journal of Pediatric Surgery2009，，： | 2 |
| 4 | Coordinated Control Architecture for Motion Management in ADAS Systems显示文摘Advanced driver assistance systems(ADAS) seek to provide drivers and passengers of automotive vehicles increased safety and comfort. Original equipment manufacturers are integrating and developing systems for distance keeping, lane keeping and changing and other functionalities. The modern automobile is a complex system of systems. How the functionalities of advanced driver assistance are implemented and coordinated across the systems of the vehicle is generally not made available to the wider research community by the developers and manufactures. This paper seeks to begin filling this gap by assembling open source physics models of the vehicle dynamics and ADAS command models. Additionally, in order to facilitate ADAS development and testing without having access to the details of ADAS, a coordinated control architecture for motion management is also proposed for distributing ADAS motion control commands over vehicle systems. The architecture is demonstrated in a case study where motion is coordinated between the steering and the braking systems, which are typically used only for a single functionality. The integrated vehicle and system dynamics using the coordinated control architecture are simulated for various driving tasks. It is seen that improved trajectory following can be achieved by the proposed coordinated control architecture. The models, simulations and control architecture are made available for open access. | Tzu-Chi Lin Siyuan Ji Charles E. Dickerson David Battersby | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，2： | 2 |
| 5 | Enlarged frontal P300 to stimulus change in panic disorder显示文摘 | McFarlane AC Weber DL Battersby M | 1996 | Biol Psychiatry1996，39，10： | 1 |
| 6 | The internal consistency and constructvalidatyof the partners in health scale: Validation of a patient rated chronic condition self-management measure显示文摘 | Petkov J Harvey P Battersby M | 2010 | Qual Life Res2010，19，7： | 1 |
| 7 | The Biodegradability and Microbial Toxicity Testing of Lubricants - some Recommendations 显示文摘 | N S Battersby | 2000 | Chemosphere2000，41，7： | 1 |
| 8 | An Inherent Biodegradability Test for Oil Products: Description and Results of an International Ring Test 显示文摘 | N S Battersby Ciccognani D M R Evans | 1999 | Chemosphere1999，38，14： | 1 |
| 9 | House of straw - It shivers, it shakes, but no earthquake can knock it down 显示文摘 | Stephen Battersby | 2009 | Current Science2009，，11： | 1 |
| 10 | Prospect of preim- plantation genetic diagnosis for heritable mitoehondrial DNA diseases显示文摘 | Dean NL Battersby BJ Ao A | 2003 | Mol Ham Rep2003，9，10： | 1 |
| 11 | Regulation of muscle mitochondrial design 显示文摘 | Moyes C D Battersby B J Leary S C | 1998 | Journal of Experimental Biology1998，201，： | 1 |
| 12 | DNA in meningioma tissues and explant cell cultures: A flow cytometric study with clinicopathological correlates 显示文摘 | Ironside JW Battersby RD Lawry J | 1987 | J Neurosurg1987，66，4： | 1 |
| 13 | Advances in critical path methods显示文摘 | Carruthers J A Battersby A | 1966 | Journal of the Operational Research Society1966，17，： | 1 |
| 14 | Metal doped silica membrane reactor: Operational effects of reaction and permeation for the water gas shift reaction显示文摘 | Scott Battersby | 2008 | J Membr Sci2008，316，： | 1 |
| 15 | Long-term follow up of progesterone receptor status in benign meningioma:a prongostic indicator of recurrence显示文摘 | Battersby RD Timperley WR | 2000 | J Neurosurg2000，92，3： | 1 |
| 16 | Expression and regulation of the prokineticins (endocrine gland-derived vascular endothelial growth factor and Bv8) and their receptors in the human endometrium across the menstrual cycle显示文摘 | Battersby S Critehley HO Morgan K | 2004 | J Clin Endocrinol Metab2004，89，5： | 1 |
| 17 | Sustained release of recombinant human growth hormone from dextran via hydrolysis of an imine bond显示文摘 | Battersby J Clark R Hancock W | 1996 | J Control Release1996，42，2： | 1 |
| 18 | Expression and regulation of the prokineticins(endocrine g-land-derived vascular endothelial growth factor and Bv8)and their receptors in the human endometrium across the menstrual cycle显示文摘 | BATTERSBY S CRITCHLEY H O MORGAN K | 2004 | J Clin Endocrinol Metab2004，89，5： | 1 |
| 19 | Clinical performance of university nursing graduates显示文摘 | BATTERSBY D HEMMINGS L | 1991 | The Australian Journal of Advanced Nursing1991，9，1： | 1 |
| 20 | Biosynthesis of vitamin B12 显示文摘 | Battersby AR Leeper FJ | 1998 | Top Curr Chem1998，195，： | 1 |
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