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| 1 | NAT2 polymorphism in Omani gastric cancer patients-risk predisposition and clinicopathological associations显示文摘AIM: To study whether N-acetyltransferase 2 (NAT2) genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and to study the clinico-pathological correlations and the prognostic signifi cance of NAT2.METHODS: Genomic DNA was extracted from peripheral blood of 100 gastric cancer patients and 100 control subjects. NAT2 genotyping was performed using DNA sequencing. The prognostic significance of NAT2 and other clinicopathological features was assessed by univariate and multivariate analyses.RESULTS: We observed no significant association between NAT2 genotypes and phenotypes and gastric cancer risk. The NAT2 phenotype polymorphisms and gastric cancer risk predisposition were not modified by concomitant H pylori infection and smoking. There was no significant association between NAT2 and clinicopathological features, and NAT2 had no independent prognostic signifi cance.CONCLUSION: In the current study, NAT2 genotypes and phenotypes are not associated with gastric cancer risk predisposition. Moreover NAT2 phenotypes had no clinicopathological associations or prognostic signif icance. | Mansour S Al-Moundhri Mohamed Al-Kindi Maryam Al-Nabhani Bassim Al-Bahrani Ikram A Burney Ali Al-Madhani Shyam S Ganguly Misbah Tanira | 2007 | World Journal of Gastroenterology2007,13,19: | 5 |
| 2 | Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk显示文摘AIM:To investigate the associations between CDH1 gene polymorphisms and gastric cancer(GC) risk predisposition.METHODS:We analyzed four CDH1 polymorphisms(+54 T>C,-160 C>A,-616 G>C,-3159 T>C) in an Omani population,by extraction of genomic DNA from the peripheral blood of 192 patients with GC and 170 control participants and performed CDH1 genotyping using DNA sequencing.RESULTS:CDH1-160-AA genotype was associated with an increased risk of GC(OR = 3.6,95% CI:1.1-11.8)(P = 0.03).There was no significant association between the other polymorphisms and GC risk.The haplotype analysis of +54 T>C,-160 C>A,-616 G>C,-3159 T>C genotypes revealed that the OR of CCGC and CAGC haplotypes was 1.5(95% CI:0.7-3.5) and 1.5(95% CI:0.2-3.0),but did not reach statistical significance.CONCLUSION:The current study suggests that the-160 AA genotype was associated with an increased risk of GC in Oman. | Mansour S Al-Moundhri Manal Al-Khanbashi Mohammed Al-Kindi Maryam Al-Nabhani Ikram A Burney Abdulaziz Al-Farsi Bassim Al-Bahrani | 2010 | World Journal of Gastroenterology2010,16,27: | 4 |
| 3 | Study of the Formation of Adiabatic Shear Bands in Steels显示文摘 | M Nabil Bassim | 2001 | Journal of Materials Processing Technology2001,119,: | 1 |
| 4 | Tympanostomy tube obs-truction related to ototopical drug therapy显示文摘 | BASSIM M K DRAKE A F | 2005 | Ear Nose Throat J2005,84,: | 1 |
| 5 | Study of the relationship between fracture toughness (JIC) and bulge ductility显示文摘 | M R Bayoumi M N Bassim | | 0,,: | 1 |
| 6 | Minimal stimulation using recombinant follicle-stimulating hormone and a gonadotropin releasing hormone antagonist in women of advanced age显示文摘 | Weghofer A Margreiter M Bassim S | 2004 | Fertil Steril2004,81,: | 1 |
| 7 | False-positive magnetic resonance imaging in the diagnosis of vestibular schwannoma显示文摘 | House JW Bassim MK Schwartz M | 2008 | OtolNeurotol2008,29,: | 1 |
| 8 | Dynamic mechanical behavior of pure titanium显示文摘 | Li Qiaug Xu Y B Bassim M N | 2004 | Journal of Materials Processing Technology2004,,30: | 1 |
| 9 | Determination of fracture toughness JIC under quasi-static and dynamic loading conditions using wedge loaded specimens显示文摘 | Bayoumi M R Kleppaczko J R Bassim M N | 1984 | Journal of Testing and Evaluation1984,12,5: | 1 |
| 10 | False-positive magnetic resonance imaging in the diagnosis of vestibular schwannoma 显示文摘 | House JW Bassim MK Schwartz M | 2008 | Octo Neutotol2008,29,8: | 1 |
| 11 | The effect of microstructure on the mechanical properties and adiabatic shear band formation in a medium carbon steel显示文摘 | Cepus E Liu C D Bassim M N | 1994 | Journal De Physique IV1994,4,: | 1 |
| 12 | Fracture toughness of coal under quasi-static and impact loading显示文摘 | Klepazko J R Bassim M N Hsu T R | 1984 | Eng Fracture Mech1984,19,2: | 1 |
| 13 | Study of the Relationship of Between Fracture Toughness (JIC) and Bulge Ductility 显示文摘 | Bayoumi M R Bassim M N | 1983 | International Journal of Fracture1983,23,: | 1 |
| 14 | Acoustic emission spectra due to leaks from circular holes and rectangular slits显示文摘 | WASSEF W A BASSIM M N HOUSSNY-EMAM M | 1985 | Acoustical Society of America1985,77,3: | 1 |
| 15 | Dynamic Mechanical Behavior of Pure Titanium显示文摘 | Li Qiang Xu Y B Bassim M N | 2004 | Journal of Materials Processing Technology2004,,30: | 1 |
| 16 | Minimal stimulation using recombinant follicle-stimulating hormone and a gonadotropin releasing hormone antagonist in women of advanced age显示文摘 | Weghofer A Margreiter M Bassim S | 2004 | Fertil Steril2004,81,4: | 1 |
| 17 | Dynamic mechanical properties in relation to adiabatic shear band formation in titanium alloy-Ti17 显示文摘 | Li Qiang Xu Yongbo Bassim M N | 2003 | Materials Science and Engineering A2003,358,: | 1 |
| 18 | Dynamic mechanical behavior of pure titanium显示文摘 | LI Q XU Y B BASSIM M N | 2004 | Journal of Materials Processing Technology2004,,: | 1 |
| 19 | False-positive mag- netic resonance imaging in the diagnosis of estibular schwannoma 显示文摘 | House JW Bassim MK Schwartz M | 2008 | Otol Neurotol2008,29,8: | 1 |
| 20 | Cell survival and proliferation are modified by insulin-like growth factor between days 9 and 10 of mouse gestation显示文摘 | Jason L Burns A Bassim Hassan | 2001 | Development2001,128,: | 1 |