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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Harnessing the power of intellectual capital 显示文摘 | Bassi L J | 1997 | Training & Development1997，51，12： | 1 |
| 3 | Adipose-derived stromal cells(ASCs)显示文摘 | Bassi G Pacelli L Carusone R | | 0，，02： | 1 |
| 4 | Long term performance of MBR for biological nitrogen removal from synthetic municipal wastewater 显示文摘 | HOLAKOO L NAKHLA G BASSI A S | 2007 | Chemosphere2007，66，： | 1 |
| 5 | Harnessing the power of intellectual capital显示文摘 | BASSI L J | 1997 | Training & Development1997，51，12： | 1 |
| 6 | Alcoholic pancreatitis:new pathogenetic insights显示文摘 | Lucrezio L Bassi M Migliori M | 2008 | Minerva Med2008，99，4： | 1 |
| 7 | Clinical aspects and molecular basis of oxaliplatin neurotoxicity:current management and development of preventive measures显示文摘 | Gamelin E Gamelin L Bassi L | 2002 | Semin Oncol2002，29，515： | 1 |
| 8 | Liver cirrhosis:changes of Doppler wave form of hepatic veins显示文摘 | Bolondi L Li Bassi S Gaiani S | | 0，，02： | 1 |
| 9 | Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent age显示文摘 | Ricci D Volzone A | 2008 | Brain2008，131，： | 1 |
| 10 | Clinical aspects and molectdar basis of oxaliplatin neurotoxincity:Current man agement and development of preventive measures显示文摘 | Gamelin E Gamelin L Bassi L | 2002 | Semin Oncol2002，29，： | 1 |
| 11 | Long term performance of MBR for biologlcal nitrogen removal from synthetic municipal wastewater显示文摘 | Holakoo L Nakhla G Bassi A S | 2007 | Chemosphere2007，66，5： | 1 |
| 12 | Drug targeting in antiviral chemotherapy显示文摘 | Fiume L Bassi B Busi C | 1986 | Biochem Pharmcol1986，35，6： | 1 |
| 13 | Galactosylated poly(L-ly- sine) as a hepatotropie carrier of 9-beta-D-arabinofuranosylade- nine 5'-monophosphate显示文摘 | FLUME L BASSI B BUSI C | 1986 | FEBS Lett1986，203，1： | 1 |
| 14 | Doppler flowmetry in portal hypertension显示文摘 | Bolondi L Li Bassi S Gaiani S | 1990 | J Gastroenterol Hepatol1990，5，4： | 1 |
| 15 | Guidelines for the management of acute panereatitis 显示文摘 | TOOULI J BROOKE-SMITH M BASSI C et a l | 2002 | J Gastroenterol Hepatol2002，，： | 1 |
| 16 | Clinical and biological be- havior of pancreatic solid pseuctopapillary tumors: report on 31 consecutive patients 显示文摘 | Salvia R Bassi C Festa L | 2007 | J Surg Oncol2007，95，： | 1 |
| 17 | Synthesis of carbon films with controlled nanostructure by seperation of neutral clusters in supersonic beams显示文摘 | Barborini E Piseri P Bassi L A | 1999 | Chem Phys Lett1999，300，： | 1 |
| 18 | Antimicrobial-coated endotracheal tubes:an experimental study显示文摘 | Berra L Curto F Li Bassi G | 2008 | Intensive Care Med2008，34，6： | 1 |
| 19 | miR-221 affects mul- tiple cancer pathways by modulating the level of hundreds messenger RNAs 显示文摘 | Lupini L Bassi C Ferraein M | 2013 | Front Genet2013，4，： | 1 |
| 20 | Microalgaefor oil: strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor显示文摘 | Rodolfi L Chin Zittelli G Bassi N | 2009 | Biotechnol Bioeng2009，102，1： | 1 |
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