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16篇 您的检索式:作者名="Baseler M"
    题名 作者 年代 出处 被引量
1Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation.Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam 2011World Journal of Gastroenterology2011,17,33:3
2Direct observation of gold nanoparticle assemblies with the porin MspA on mica显示文摘Basel M T Dani R K Kang M 2009ACS Nano2009,3,2:1
3Ginkgo biloba protects against intermittent hypoxia-induced memory deficits and hippocampal DNA damage in rats 显示文摘Basel Abdel W Samy M 2012Phytomedicine2012,19,5:1
4Stem cell-based photodynamic therapy显示文摘Shrestha T B Seo G M Basel M T 2012Photochem Photobiol Sci2012,11,7:1
5Omega-3 polyunsaturated fatty acids in large doses attenuate seizures,cognitive impairment,and hippocampal oxidative DNA damage in young kindled rats显示文摘BASEL A ABDEL-WAHAB JOBRAN M 2015J Neurosci Lett2015,584,:1
6Cyclin AI shows age-related expression in benign tonsils, HPV16-dependent overexpression in HNSCC and predicts lower recurrence rate in HNSCC independently of HPV 16 显示文摘Weiss D Koopmann M Basel T 2012BMC Cancer2012,12,:1
7A Nonlinear PID Control Scheme for Hard Disk Drive Servosystems显示文摘BASEL M ISAYED MUHAMMAD A HAWWA 2007Control and Automation2007,,07:1
8Oxidative stress and atrial fibrillation after cardiac surgery: A case-control study显示文摘Basel R Hasan O Shigetoshi M 2007The Annals of Thoracic Surgery2007,84,4:1
9Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages显示文摘Wang H Shrestha T B Basel M T 2012Beilstein Journal of Nanotechnology2012,3,:1
10Effect of starch addition on the properties of low density polyeth- ylene for developing environmentally degradable plastic bags显示文摘Ruhul H M Basel F A S Mamdouh A H 2011J Chem Eng2011,26,1:1
11Distal limb malformations: underlying mechanisms and clinical associa tions 显示文摘Sifakis S Basel D Ianakiev P Kilpatriek M Tsipouras P 2001Clin Genet2001,60,3:1
12Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4^+ and CD8^+ T cell turnover in HIV-infected patients显示文摘Lempicki R A Kovacs J A Baseler M W 2000Proc Natl Acad Sci USA2000,97,13:1
13HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAA T) in patients with a history of sustained viral suppression 显示文摘Davey RT Bhat N Yoder C Chun TW Metcalf JA Dewar R Natarajan V Lempicki RA Adelsberger JW Miller KD Kovacs JA Polis MA Walker RE Falloon J Masur H Gee D Baseler M Dimitrov DS Fauci AS Lane HC 1999Proc Natl Acad Sci USA1999,96,15:1
14Treatment with interferon-al- pha2b and ribavirin improves outcome in mers-cov-infec- ted rhesus macaques显示文摘Falzarano D de Wit E Rasmussen A L Feldmann F Okumura A Scott D P Brining D Bushmaker T Mar- tellaro C Baseler L Benecke A G Katze M G Mun ster V J Feldmann H 2013Nat Med2013,19,10:1
15Customer- to- customer in- teractions: broadening the scope of word of mouth research 显示文摘Libai B Boltcu R Basel M S 2010Jour- nal afServiceResearch2010,13,3:1
16Colton a bio2 sensor based on magnetoresistance technology显示文摘BASEL T D R LEE G U NATESAN M 1998Biosensors & Bioelectronics1998,13,73:1
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