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| 1 | Global secretome analysis identifies novel mediators of bone metastasis显示文摘骨头是稳固的肿瘤的远转移的一个最普通的地点。分泌蛋白质被知道影响在变形癌症房间和骨头基质之间的病理学的相互作用。为了包括地介绍,分泌了与骨头转移联系的蛋白质,我们使用了量、非量的集体 spectrometry 全球性分析改变从多重种类和癌症的变形能力打的骨头的九根细胞线的 secretomes。由比较父母房间和他们的骨头的 secretomes 变形衍生物,我们识别了特别地在这些房间线与骨头转移被联系的分泌蛋白质。我们然后合并了大临床的转移数据集的生物信息的分析获得强烈与临床、试验性的骨头转移被联系的几个功能的班的候选人小说骨头转移蛋白质的一张表。选择蛋白质的功能的确认显示在 vivo,骨头转移能被高表示支持(1 ) 唾液的 cystatins CST1, CST2,和 CST4;(2 ) plasminogen 使活跃之物小块地和 PLAU;或(3 ) 骨胶原功能蛋白质 PLOD2 和 COL6A1。总的来说,我们的学习揭开了骨头转移并且因此的几个新分泌调停人证明 secretome 分析是为新奇 biomarkers 和候选人的鉴定的一个强大的方法治疗学的目标。 | Maria Andres Blanco Gary LeRoy Zia Khan Ma a Ale kovi Barry M Zee Benjamin A Garcia Yibin Kang | 2012 | Cell Research2012，22，9： | 12 |
| 2 | Surgical management of primary and recurrent retroperitoneal liposarcoma显示文摘 | Neuhaus SJ Barry P Clark MA | | 0，，02： | 2 |
| 3 | Small animal model for investination of subaraehnoid hemorrhage and cerebral vasospasm 显示文摘 | Barry KJ Gonjian MA stein BM | 1979 | Stroke1979，10，5： | 1 |
| 4 | Small animal model for investigation of subarachnoid hemorrhage and cerebral vasospasm 显示文摘 | Barry KJ Gogjian MA Stein BM | 1979 | Stroke1979，10，5： | 1 |
| 5 | Small animal model for investination of subarachnoid hemorrhage and cerebral vasospasm 显示文摘 | Barry K J Gonjian MA stein BM | 1979 | Stroke1979，10，5： | 1 |
| 6 | Poly (ethylenimine)-mediated transfection:a new paradigm for gene delivery显示文摘 | Barry MA Sadhu P | 2000 | JBiomed Mater Res2000，51，3： | 1 |
| 7 | Passive acoustic detection and measurement of rainfall at sea显示文摘 | BARRY B MA JEFFREY A NYSTUEN | 2005 | Journal of Atmospheric and Oceanic Technology2005，22，： | 1 |
| 8 | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole ST Brosch R Parkhill J Garnier T Churcher C Harris D Gordon SV Eiglmeier K Gas S Barry CE Tekaia F Badcock K Basham D Brown D Chillingworth T Connor R Davies R Devlin K Feltwell T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Krogh A Mclean J Moule S Murphy L Oliver K Osborne J Quail MA Rajandream MA Rogers J Rutter S Seeger K Skelton J Squares R Squares S Sulston JE Taylor K Whitehead S Barrell BG | 1998 | Nature1998，393，6685： | 1 |
| 9 | Detection and signification of intraoperafine and postoperative myocardial ischemiainperipheralvascular surgery显示文摘 | Barry J Greager MA | 1992 | JAMA1992，268，2： | 1 |
| 10 | Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia显示文摘 | Barry MA Behnke CA Eastman A | 1990 | Biochem Pharmacol1990，40，10： | 1 |
| 11 | Activation of apoptosis by anticancer drugs显示文摘 | Behne CA Eastman A | 1990 | Biochem Pharmacol1990，40，： | 1 |
| 12 | Activation of apoptosis by anticancer drugs显示文摘 | Barry MA Behnke CA Eastman A | 1990 | Biochem pharmacol1990，40，65： | 1 |
| 13 | Surgical management of primary and recurrent retroperitoneal liposarcoma 显示文摘 | Neuhaus SJ Barry P Clark MA | 2005 | Br J Surg2005，92，2： | 1 |
| 14 | Precision and accuracy on fluconazole susceptibility testing by broth microdilution test,and disk diffusion methods显示文摘 | Pfaller MA Rennie R | 2002 | Antimicrob Agents Chem-other2002，46，6： | 1 |
| 15 | Actiavation of apoptosis by anticancer drugs 显示文摘 | Barry MA Behne CA Eastman A | 1990 | Biochem Pharmacol1990，40，： | 1 |
| 16 | Activation of apoptosis by anticancer drugs 显示文摘 | Barry MA Behne CA Eastman A | 1990 | Biochem Pharmacol1990，40，： | 1 |
| 17 | Surgical management of primary and recurrent retroperitoneal liposarcoma显示文摘 | Neuhaus SJ Barry P Clark MA | 2005 | Br J Surg2005，92，2： | 1 |
| 18 | Poly(ethylenimine)-mediated transfection:a new paradigm for gene delivery 显示文摘 | Godbey WT Barry MA Saggau P | 2000 | J Biomed Mater Res2000，51，： | 1 |
| 19 | Surgical management of primary and recurrent retroperitoneal liposarcoma显示文摘 | Neuhaus SJ Barry P Clark MA | 2005 | Br J Surg2005，92，2： | 1 |
| 20 | Analysi of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin显示文摘 | Sorenson CM Barry MA Eastman A | 1990 | Journal of The National Cancer Institute1990，82，9： | 1 |
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