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| 1 | Outcome in obscure gastrointestinal bleeding after capsule endoscopy显示文摘AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. | Alex Caas-Ventura Lucia Márque Xavier Bessa Josep Maria DedeuDepartment of Gastroenterology Hospital del Mar Research Institute Pompeu Fabra University Marc Puigvehí Sílvia Delgado-Aros Ines Ana Ibáez Agustin Seoane Luis Barranco Felipe Bory Montserrat Andreu Begoa González-Suárez | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 4 |
| 2 | GSTM3, but not IZUMO1, is a cryotolerance marker of boar sperm显示文摘Background: Cryopreservation is currently the most efficient method for long-term preservation of mammalian gametes and is extensively used in swine artificial insemination(AI) centres. However, it is well-known that cryopreservation procedures induce changes in the water phase in both intra and extracellular compartments,which alter the content and localisation of several proteins and ends up curtailing the structural integrity of functional sperm(i.e., cryoinjuries). Alterations and deficiencies of sperm-oocyte binding proteins during gamete recognition are one of the causes of reproductive failure both in vitro and in vivo. In this sense, characterisation of cryopreservation effects upon oocyte-binding proteins of sperm, such as IZUMO1 and GSTM3, is essential when assessing the impact of this technique in swine reproduction.Results: Cryopreservation was found to induce changes in the localisation of IZUMO1 and GSTM3 in boar sperm.However, the relative content of both proteins was not altered after thawing. Furthermore, whereas IZUMO1 content was found not to be related to the cryotolerance of boar sperm, GSTM3 content was observed to be higher in poor(PFE) than in good(GFE) freezability ejaculates in both pre-frozen(1.00 INT·mm^2± 0.14 INT·mm^2 vs.0.72 INT·mm^2± 0.15 INT·mm^2;P < 0.05) and post-thawed(0.96 INT·mm^2± 0.20 INT·mm^2 vs. 70 INT·mm^2± 0.19 INT·mm^2;P < 0.05) samples. Moreover, GSTM3 levels were found to be higher in those spermatozoa that exhibited low mitochondrial activity, high reactive oxygen species(ROS) production, and high membrane lipid disorder postthaw(P < 0.05).Conclusions: The difference in GSTM3 content between GFE and PFE, together with this protein having been found to be related to poor sperm quality post-thaw, suggests that it could be used as a cryotolerance marker of boar spermatozoa. Furthermore, both IZUMO1 and GSTM3 relocate during cryopreservation, which could contribute to the reduced fertilising capacity of frozen-thawed boar sperm. | Marc Llavanera Ariadna Delgado-Bermúdez Beatriz Fernandez-Fuertes Sandra Recuero Yentel Mateo Sergi Bonet Isabel Barranco Marc Yeste | 2019 | Journal of Animal Science and Biotechnology2019，10，4： | 4 |
| 3 | EIS study of the corrosion behaviour of zinc- based coatings on steel in quiescent 3% NaCl solution 显示文摘 | Barranco V Feliu S J | 2004 | Corrosion Science2004，46，： | 1 |
| 4 | Solid-phase clean-up in the liquid chromatographic determination of polycyclic aromatic hydrocarbons in edible oils 显示文摘 | Barranco A Alonso-Salces R Bakkali A | 2003 | Journal of Chromatography A2003，988，： | 1 |
| 5 | Pressurized liquid extraction for the determination of polyphenols in apple显示文摘 | ALONSO-SALCES R M KORTA E BARRANCO A BERRUETA L A GALLO B VICENTE F | 2001 | Journal of Chromatography A2001，933，1： | 1 |
| 6 | A new char combustion kinetic model (2): Empirical validation 显示文摘 | ROJAS A BARRAZA J BARRANCO R | 2012 | Fuel2012，96，： | 1 |
| 7 | Solid - phase clean - up in the liquid chromato- graphic determination of polycyclic aromatic hydrocarbons in edible oils显示文摘 | BARRANCO A ALONSO -SALCES R M BAKKAL A | 2003 | J Chromatogr A2003，988，： | 1 |
| 8 | Consensus document on the diagnosis of severe uncontrolled asthma显示文摘 | Barranco P P6rez-Franc6s C Quirce S | 2012 | J Investig Allergol Clin hnmunol2012，22，7： | 1 |
| 9 | Usefulness of exhaled nitric oxide for diagnosing asthma 显示文摘 | Pedrosa M Cancelliere N Barranco P | 2010 | J Asthma2010，47，7： | 1 |
| 10 | Microwave pyrolysis of wood pellets显示文摘 | ROBINSON J P KINGMAN S W BARRANCO R | 2010 | Industrial & Engineering Chemistry Research2010，49，2： | 1 |
| 11 | Suitability and effectiveness of single layer centrifugation using Androcoll-P in the cryopreservation protocol for boar spermatozoa显示文摘 | Maria J. Martinez-Alborcia Jane M. Morrell Maria A. Gil Isabel Barranco Carolina Maside Diego V. Alkmin Inmaculada Parrilla Emilio A. Martinez Jordi Roca | 2013 | Animal Reproduction Science2013，，： | 1 |
| 12 | Irritable bowel syndrome in a community -based study in southern Europe 显示文摘 | Caballero - Plasencia Valenzuela - Barranco M patients with dyspepsia A M Sofos- Kontoyannis S | 1999 | European journal of gastroenterology & hepatology1999，11，5： | 1 |
| 13 | Overcoming iron chlorosis in olive and peach trees using a low-pressure trunk injection method显示文摘 | Ferxnandexz-Escobar R Barranco D Benlloch M | 1993 | Hort Science1993，28，3： | 1 |
| 14 | Study of degradation mechanisms of a protective lacquer film formulated with phosphating reagents applied on galvanized steel,galvanneal and galfan in exposure UV/condensation test显示文摘 | S Feliu V Barranco | 2004 | Surface and coatings technology2004，182，： | 1 |
| 15 | Cyto-kine expression by macrophages in the lung of pigs in-fected with the porcine reproductive and respiratorysyndrome virus显示文摘 | Gomez-Laguna J Salguero F J Barranco I | 2010 | Comp Path2010，，： | 1 |
| 16 | CD30 antigen expression in cutaneous inflammatory infiltrates of scabies: a dynamic immunophenotypic pattern that should be distinguished from lymphomatoid papulosis 显示文摘 | Gallardo F Barranco C Toll A | 2002 | J Cutan Pathoh2002，29，7： | 1 |
| 17 | An active star topology for improving fault confinement in CAN networks显示文摘 | Barranco M Proenza J | 2006 | IEEE Trans Ind Informat2006，2，2： | 1 |
| 18 | MUC4 expression is increased in dysplastie cervical disorders 显示文摘 | Lopez- Ferrer A Alameda F Barranco C | 2001 | Hum Pathol2001，32，11： | 1 |
| 19 | Electronic structure of few-electron concentricdouble quantum rings 显示文摘 | Climente J I Planelles J Barranco M Malet F PiM | 2006 | Phys Rev B2006，73，23： | 1 |
| 20 | Survival and cell kinetics effects of adriamycin on mammalian cells显示文摘 | BARRANCO S C GERNER E W BURK K H | 1973 | Cancer Res1973，33，： | 1 |
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