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| 1 | Functions of NKG2D in CD8^(+) T cells: an opportunity for immunotherapy显示文摘Natural killer group 2 member D(NKG2D)is a type II transmembrane receptor.NKG2D is present on NK cells in both mice and humans,whereas it is constitutively expressed on CD8+T cells in humans but only expressed upon T-cell activation in mice.NKG2D is a promiscuous receptor that recognizes stress-induced surface ligands.In NK cells,NKG2D signaling is sufficient to unleash the killing response;in CD8+T cells,this requires concurrent activation of the T-cell receptor(TCR).In this case,the function of NKG2D is to authenticate the recognition of a stressed target and enhance TCR signaling.CD28 has been established as an archetype provider of costimulation during T-cell priming.It has become apparent,however,that signals from other costimulatory receptors,such as NKG2D,are required for optimal T-cell function outside the priming phase.This review will focus on the similarities and differences between NKG2D and CD28;less well-described characteristics of NKG2D,such as the potential role of NKG2D in CD8+T-cell memory formation,cancer immunity and autoimmunity;and the opportunities for targeting NKG2D in immunotherapy. | Kushal Prajapati Cynthia Perez Lourdes Beatriz Plaza Rojas Brianna Burke Jose A Guevara-Patino | 2018 | Cellular & Molecular Immunology2018，15，5： | 7 |
| 2 | UPLAND EROSION MODELING WITH CASC2D-SED显示文摘Developed at Colorado State University, CASC2D-SED is a physically-based model simulating the hydrologic response of a watershed to a distributed rainfall field. The time-dependent processes include: precipitation, interception, infiltration, surface runoff and channel routing, upland erosion, transport and sedimentation. CASC2D-SED is applied to Goodwin Creek, Mississippi. The watershed covers 21 km2 and has been extensively monitored both at the outlet and at several internal locations by the ARS-NSL at Oxford, MS. The model has been calibrated and validated using rainfall data from 16 meteorological stations, 6 stream gauging stations and 6 sediment gauging stations. Sediment erosion/deposition rates by size fraction are predicted both in space and time. Geovisualization, a powerful data exploration technique based on GIS technology, is used to analyze and display the dynamic output time series generated by the CASC2D-SED model. | Pierre JULIEN Rosalía ROJAS | 2002 | International Journal of Sediment Research2002，17，4： | 7 |
| 3 | Mitochondrial markers for the detection of four duck species and the specific identification of Muscovy duck in meat mixtures using the polymerase chain reaction显示文摘 | Irene Martín Teresa García Violeta Fajardo Inés López-Calleja María Rojas Pablo E. Hernández Isabel González Rosario Martín | 2007 | Meat Science2007，，4： | 2 |
| 4 | Oxidative stress in tumor microenvironment--Its role in angiogenesis显示文摘The tumor angiogenesis process is believed to be dependent on an 'angiogenic switch' formed by a cascade of biologic events as a consequence of the 'cross-talk' between tumor cells and several components of local microenvironment including endothelial cells, macrophages, mast cells and stromal components. Oxidative stress represents an important stimulus that widely contributes to this angiogenic switch, which is particularly relevant in lungs, where oxidative stress is originated from different sources including the incomplete reduction of oxygen during respiration, exposure to hypoxia/reoxygenation, stimulated resident or chemoattracted immune cells to lung tissues, as well as by a variety of chemicals compounds. In the present review we highlight the role of oxidative stress in tumor angiogenesis as a key signal linked to other relevant actors in this complex process. | Armando ROJAS Raul SILVA Hectcr FIGUEROA Miguel A MORAINES | 2008 | 中国肺癌杂志2008，11，3： | 2 |
| 5 | 龙胆属植物Gentiana spathacea中龙胆苦苷的平滑肌松驰作用显示文摘 | Rojas A | 2001 | 国外医药(植物药分册)2001，16，6： | 2 |
| 6 | Can testosterone therapy be offered to men on active surveillance for prostate cancer? Preliminary results显示文摘这份报告在活跃监视上在 T 缺乏的人的一个队与 T 治疗介绍我们的经验(作为) 为 Gleason 3 + 3 并且 Gleason 3 + 4 前列腺癌症(PCa ) 。回顾的图表评论与 T 缺乏识别了 28 个人经历 T 治疗(T 组) 至少 6 个月了当时在上至于 PCa。96 个人在上的一个比较组至于有未经治疗的 T 缺乏的 PCa (别组织) 在一样的机构被识别。同样协议跟随了修改爱泼斯坦标准和有小量的 Gleason 3 + 的一个单个核心的人的允许的包括 4 PCa。吝啬的年龄是 59.5 和 61.3 年,并且意味着后续是为 T 的 38.9 和 42.4 个月并且不分别地组织。在 T 组的所有 28 个人, 3 (10.7%) 人们在格利森分数开发了增加当时在上作为。22,在 T 的人与 Gleason 3 + 组织 3 疾病, 7 (31.8%) 人们包括开发了 Gleason 3 + 的 3 个人(13.6%) 开发了活体检视前进 4 PCa。有 Gleason 3 + 的 6 个人在基线的 4 疾病, 2 (33.3%) 人们在肿瘤体积开发了增加,并且任何一个都没发展在 Gleason 3 + 以外升级 4。所有 96 个人在别组织有的 Gleason 3 + 在基线的 3 疾病并且,(44.7%) 43 开发了活体检视前进,包括有升级到 Gleason 7 的 9 个人(9.38%)(3 + 4 ) 。活体检视前进率为组和历史的控制是类似的。在人在上的活体检视前进作为在 3 年由 T 治疗显得未受影响。在 T 缺乏的人在上的 T 治疗的未来的控制安慰剂的试用作为应该被认为给对待的人经验丰富的征兆的好处。 | Ravi Kacker Mariam Hult Ignacio F San Francisco William P Conners Pablo A Rojas William C Dewolf Abraham Morgentaler | 2016 | Asian Journal of Andrology2016，18，1： | 2 |
| 7 | Endotoxin-induced lung injury in mice : structural, functional, and biochemical responses显示文摘 | Rojas M Woods C R Mora A L | 2005 | Am J Physiol Lung Cell Mol Physiol2005，288，： | 1 |
| 8 | A prospective randomized study comparing D2 total gastrectomy versus D2 total gastrectomy plus splenectomy in 187 patients with gastric carcinoma显示文摘 | Csendes A Burdiles P Rojas J Braghetto I Diaz JC Maluenda F | 2002 | Surgery2002，131，4： | 1 |
| 9 | Trapping of aromatic compounds by adsorption on hydrophobic sorbents显示文摘 | Rojas J A Voilley A 1996 | 1996 | Sep Sci Technol1996，31，18： | 1 |
| 10 | Influence of hydrocolloids on dough rheology and bread quality 显示文摘 | ROSELL C M ROJAS J A DE BARBER C B | 2001 | Food Hydrocolloids2001，15，1： | 1 |
| 11 | Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor 显示文摘 | ROJAS C STATHIS M THOMAS A G | 2008 | Anesth Analg2008，107，2： | 1 |
| 12 | Desensitization of pituitary gonadotropin secretion by agonist-induced inactivation of voltage-sensitive calcium channels 显示文摘 | Stojilkovic S S Rojas E Stutzin A | 1989 | Journal of Biological Chemistry1989，264，10： | 1 |
| 13 | Pendimethalin and oxyfluorfen degradation under two irrigation conditions over four years application 显示文摘 | Alister C A Gomez P A Rojas S | 2009 | Journal of Environment Science Health B2009，44，： | 1 |
| 14 | Improving the surface fin-ish of concave and convex surfaces using a ball burnishing process显示文摘 | Travieso J A Dessein G Rojas H A | 2011 | Materials and Manufacturing Processes2011，26，12： | 1 |
| 15 | Cyclooxygenase-2 in epilepsy显示文摘 | ROJAS A JIANG J GANESH T | 2014 | Epilepsia2014，55，： | 1 |
| 16 | Advanced glycation and endothelial functions:a link towards vascular complications in diabetes显示文摘 | Rojas A Morales MA | 2004 | Life Sci2004，76，7： | 1 |
| 17 | Frequencies of virus-specific CD4 + and CD8 + T lymphocytes secreting gamma interferon after acute natural rotavirus infection in children and adults显示文摘 | Jaimes MC Rojas OL González AM Cajiao I Charpilienne A Pothier P | 2002 | J Virol2002，76，10： | 1 |
| 18 | Carbogen and nicotinamide as radiosensitizes in a murine mammary carcinoma using conventional and accelerated radiotherapy 显示文摘 | Rojas A Hirst VK Calvert AS | 1996 | Int J Radiat Oncol Biol Phys1996，34，2： | 1 |
| 19 | Effects of processing on kiwifruit dynamicrheological behaviour and tissues tructure显示文摘 | Gerschenson L N Rojas A M Marangoni A G | 2001 | Food Research International2001，34，： | 1 |
| 20 | 查看详情显示文摘 | Habibi Y Lucia L. A Rojas O | | 0，，： | 1 |
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