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| 1 | Colorectal liver metastases: Current management and future perspectives显示文摘The liver is the commonest site of metastatic disease for patients with colorectal cancer,with at least 25%developing colorectal liver metastases(CRLM)during the course of their illness.The management of CRLM has evolved into a complex field requiring input from experienced members of a multi-disciplinary team involving radiology(cross sectional,nuclear medicine and interventional),Oncology,Liver surgery,Colorectal surgery,and Histopathology.Patient management is based on assessment of sophisticated clinical,radiological and biomarker information.Despite incomplete evidence in this very heterogeneous patient group,maximising resection of CRLM using all available techniques remains a key objective and provides the best chance of long-term survival and cure.To this end,liver resection is maximised by the use of downsizing chemotherapy,optimisation of liver remnant by portal vein embolization,associating liver partition and portal vein ligation for staged hepatectomy,and combining resection with ablation,in the context of improvements in the functional assessment of the future remnant liver.Liver resection may safely be carried out laparoscopically or open,and synchronously with,or before,colorectal surgery in selected patients.For unresectable patients,treatment options including systemic chemotherapy,targeted biological agents,intraarterial infusion or bead delivered chemotherapy,tumour ablation,stereotactic radiotherapy,and selective internal radiotherapy contribute to improve survival and may convert initially unresectable patients to operability.Currently evolving areas include biomarker characterisation of tumours,the development of novel systemic agents targeting specific oncogenic pathways,and the potential reemergence of radical surgical options such as liver transplantation. | Jack Martin Angelica Petrillo Elizabeth C Smyth Nadeem Shaida Samir Khwaja HK Cheow Adam Duckworth Paula Heister Raaj Praseedom Asif Jah Anita Balakrishnan Simon Harper Siong Liau Vasilis Kosmoliaptsis Emmanuel Huguet | 2020 | World Journal of Clinical Oncology2020，11，10： | 5 |
| 2 | Collision-Minimizing CSMA and Its Applications to Wireless Sensor Networks 显示文摘 | Tay Y C Jamieson K Balakrishnan H | 2004 | IEEE Journal on Selected Areas in Communications2004，22，6： | 1 |
| 3 | Point and Interval estimation for Gaussian distribution based on progressively type-lI censored samples 显示文摘 | Balakrishnan N Kannan N Lin C T and Ng H K T | 2003 | IEEE Transactions on Reliability2003，52，： | 1 |
| 4 | The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel 显示文摘 | Mu C F Balakrishnan P Cui F D | 2010 | Biomaterials2010，31，8： | 1 |
| 5 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 6 | Tensile fracture and thermal conductivity characterization of toughened epoxy/CNT nanocomposites 显示文摘 | Balakrishnan A Saha M C | 2011 | Ma- terials Science and Engineering: A2011，528，3： | 1 |
| 7 | Collision-Minimi- zing CSMA and Its Applications to Wireless Sensor Networks 显示文摘 | Tay Y C Jamieson K and Balakrishnan H | | IEEE Journal on Selected Areas in Communications0，2004，： | 1 |
| 8 | Mis-speeification analyses of gamma and Wiener degradation processes显示文摘 | TSAI C C TSENG S T BALAKRISHNAN N | 2011 | Jour- nal of Statistical Planning and Inference2011，141，12： | 1 |
| 9 | Sustained response to etanercept after failing infliximab,in a patient with relapsing polychondritis with tracheomalacia显示文摘 | Subrahmanyam P Balakrishnan C Dasgupta B | 2008 | Scand J Rheumatol2008，37，3： | 1 |
| 10 | Experiments on composite beams 显示文摘 | Chapman J C Balakrishnan S | 1964 | The Structural Engineer1964，42，11： | 1 |
| 11 | Piezoelectric actuation:state of the art显示文摘 | NIEZRECKI C BREI D BALAKRISHNAN S | 2001 | The Shock and Vibration Digest2001，33，4： | 1 |
| 12 | Time-dependent quantum mechanical approach to reactive scattering and related processes显示文摘 | Balakrishnan N Kalyanaraman C Sathyamurthy N | 1997 | Phys Rep1997，280，： | 1 |
| 13 | Production, partial characterization and use of fungal cellulase-freexylanases in pulp bleaching显示文摘 | Christov L P Szakacs G Balakrishnan C H | 1999 | Process Biochemistry1999，34，： | 1 |
| 14 | Protein secondary structure from deep-UV resonance Raman spectroscopy 显示文摘 | Huang C Balakrishnan G Spiro T G | 2006 | J Raman Spee- trosc2006，37，13： | 1 |
| 15 | Determination of defense mechanism in seedlings treated under UV-B radiation显示文摘 | Ravindran K C Indrajith A Balakrishnan V | 2008 | African Crop Science Journal2008，16，2： | 1 |
| 16 | C5a delays apoptosis of human neutrophils via an extracellular signal-regulated kinase and Bad-mediated signalling pathway显示文摘 | PERIANAYAGAM M C BALAKRISHNAN V S PEREIRA B J | 2004 | Eur J Clin Invest2004，34，1： | 1 |
| 17 | Nickel assisted sintering of Ti3SiC2 powder under pressureless conditions显示文摘 | PANIGRAHI B B REDDY N S BALAKRISHNAN A CHO M C GRACIO J J | 2010 | Journal of Alloys and Compounds2010，505，1： | 1 |
| 18 | Improved pul- monary function following pirfenidone treatment in a patient with pro- gressive interstitial lung disease associated with systemic sclerosis 显示文摘 | Udwadia ZF Mullerpattan JB Balakrishnan C | 2015 | Lung India2015，32，1： | 1 |
| 19 | Jacob V S, etal, Comparative performance of the FSCL neural net and K - means algorithm for market segmentation 显示文摘 | Balakrishnan P V S Copper M C | 1996 | European Joural of Operational Research1996，93，2： | 1 |
| 20 | Facopt: a user friendly facility layout optimization system显示文摘 | Balakrishnan J Cheng C H Wong K F | 2003 | Computers & Operalions Research2003，30，21： | 1 |
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