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| 1 | 分子修饰的重组百日咳毒素S1亚单位的生物学和免疫学特性显示文摘目的:对重组杆状病毒表达的经多种信号序列修饰的天然和变异百日咳毒素(PT)S1亚单位(rS1)的生物学及免疫学特性作出评价。方法:应用生物化学和免疫学技术与方法对这些rS1的酶活性、分泌性和免疫原性等做了系统鉴定。结果:rS1变异子无可检出的酶活性;所有rS1均不能由细胞分泌,可从细胞膜组分中大量检出,但不能从可溶性胞浆蛋白组分或细胞培养上清中检出;rS1分子内部含有3个疏水性区域;rS1虽不能与B寡聚体结合形成PT全毒素,但均能诱导抗PT免疫应答。结论:这些rS1极可能以膜蛋白形式存在,其非分泌性与分子内部的疏水性区域有关;所有rS1均保持其免疫原性。 | 于康震 Burnette W N Kaslow H R Yilma T D | 1999 | 中国免疫学杂志1999，15，4： | 4 |
| 2 | Diagnosis and management of acute myeloid leukemia in adults:recommendations from an international expert panel,on behalf of the European LeukemiaNet显示文摘 | Dhner H Estey EH Amadori S Appelbaum FR Büchner T Burnett AK Dombret H Fenaux P Grimwade D Larson RA Lo-Coco F Naoe T Niederwieser D Ossenkoppele GJ Sanz MA Sierra J Tallman MS Lwenberg B Bloomfield CD | 2010 | {H}Blood2010，，03： | 1 |
| 3 | Extremely high multiplicities in high-energy nucleus-nucleus collisions显示文摘 | Burnett T H Dake S Fuki M | 1983 | Phys Rev Lett1983，50，26： | 1 |
| 4 | A methodology to investigate the particulate penetration coefficient through building shell显示文摘 | TUNG T C W CHAO C Y H BURNETT J | 1999 | Atmospheric Environment1999，33，6： | 1 |
| 5 | A methodology to investigate the particulate penetration coefficient through building shell 显示文摘 | Tung T C W Chao C Y H Burnett J | 1999 | Atmospheric Environment1999，33，： | 1 |
| 6 | The association between ambient carbon monoxide levels and mortality in Toronto Canada显示文摘 | BURNETT R T PHILIPS O OZKAYNAK H | 1998 | Journal of the Air and Waste Management Association1998，48，： | 1 |
| 7 | Extremely high multiplicities in high-energy nucleus-nucleus collisions显示文摘 | BURNETT T H DAKE S FUKI M | 1983 | Phys Rev Lett1983，50，26： | 1 |
| 8 | Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy显示文摘Background The number of mobile stroke programmes has increased with evidence,showing they expedite intravenous thrombolysis.Outstanding questions include whether time savings extend to patients eligible for endovascular therapy and impact clinical outcomes.Objective Our mobile stroke unit(MSU),based at an academic medical centre in upstate New York,launched in October 2018.We reviewed prospective observational data sets over 26 months to identify MSU and non-MSU emergency medical service(EMS)patients who underwent intravenous thrombolysis or endovascular thrombectomy for comparison of angiographic and clinical outcomes.Results Over 568 days in service,the MSU was dispatched 1489 times(2.6/day)and transported 300 patients(20%of dispatches).Intravenous tissue plasminogen activator(tPA)was administered to 57 MSU patients and the average time from 911 call-to tPA was 42.5 min(±9.2),while EMS transported 73 patients who received tPA at 99.4 min(±35.7)(p<0.001).Seven MSU patients(12%)received tPA from 3.5 hours to 4.5 hours since last known well and would likely have been outside the window with EMS care.Endovascular thrombectomy was performed on 21 MSU patients with an average 911 call-to groin puncture time of 99.9 min(±18.1),while EMS transported 54 patients who underwent endovascular thrombectomy(ET)at 133.0 min(±37.0)(p=0.0002).There was no difference between MSU and traditional EMS in modified Rankin score at 90-day clinic follow-up for patients undergoing intravenous thrombolysis or endovascular thrombectomy,whether assessed as a dichotomous or ordinal variable.Conclusions Mobile stroke care expedited both intravenous thrombolysis and endovascular thrombectomy.There is an ongoing need to show improved functional outcomes with MSU care. | Matthew T Bender Thomas K Mattingly Redi Rahmani Diana Proper Walter A Burnett Jason L Burgett Joshua LEsperance Jeremy T Cushman Webster H Pilcher Curtis G Benesch Adam G Kelly Tarun Bhalla | 2022 | Stroke & Vascular Neurology2022，7，3： | 1 |
| 9 | Enhanced tunability and linewidth sharpening of plasmon resonances in hybridized metallic ring/disk nanocavities显示文摘 | FENG H NORDLANDER P BURNETT M T | 2007 | Physical Review:B2007，76，24： | 1 |
| 10 | GPS time synchronization in school-network cosmic ray detectors显示文摘 | Burnett T H Gran R | 2004 | Nuclear Science2004，，3： | 1 |
| 11 | Changes in body mass and body composition in pre-hibernating little brown bats(Myotis lucifugus)显示文摘 | KUNZ T H WRAZEN J A BURNETT C D | 1998 | Ecoscience1998，5，1： | 1 |
| 12 | Risk of incident diabetes in relation to long-term exposure to fine particulate matter in Ontario,Canada显示文摘 | CHEN H BURNETT R T KWONG J C | 2013 | Environ Health Perspect2013，121，7： | 1 |
| 13 | A methodology toinvestigate the particulate penetration coefficient through building shell 显示文摘 | Tung T C W Chao C Y H Burnett J | 1999 | Atmospheric Environment1999，33，6： | 1 |
| 14 | Control of the receding meniscus in immersion lithography显示文摘 | BURNETT H SHEDD T NELLIS G | 2005 | Journal of Vacuum Science and Technology B2005，23，6： | 1 |
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