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1MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis b- and c-related-hepatocellularcarcinoma显示文摘Aim of the present review is to summarize the current knowledge about the potential relationship between mi RNAs and hepatitis B virus(HBV)-hepatitis C virus(HCV) related liver diseases. A systematic computerbased search of published articles, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Statement, was performed to identify relevant studies on usefulness of serum/plasma/urine mi RNAs, as noninvasive biomarkers for early detection of HBV and HCV-induced hepatocellular carcinoma(HCC) development, as well as for its prognostic evaluation. The used Medical Subject Headings terms and keywords were: 'HBV', 'HCV', 'hepatocellular carcinoma', 'micro RNAs', 'mi RNAs', 'diagnosis', 'prognosis', 'therapy', 'treatment'. Some serum/plasma mi RNAs, including mi R-21, mi R-122, mi-125a/b, mi R-199a/b, mi R-221, mi R-222, mi R-223, mi R-224 might serve as biomarkers for early diagnosis/prognosis of HCC, but, to date, not definitive results or well-defined panels of mi RNAs have been obtained. More well-designed studies, focusing on populations of different geographical areas and involving larger series of patients, should be carried out to improve our knowledge on the potential role of mi RNAs for HCC early detection and prognosis.Sirio Fiorino Maria Letizia Bacchi-Reggiani Michela Visani Giorgia Acquaviva Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Luca Di Tommaso Arrigo Bondi Sergio Sabbatani Andrea Domanico Carlo Fabbri Paolo Leandri Annalisa Pession Elio Jovine Dario de Biase 2016World Journal of Gastroenterology2016,22,15:25
2Effect of omeprazole and domperidone on adult asthmatics with gastroesophageal reflux显示文摘AIM: To study the effect of combined omeprazole (Ome) and domperidone (Dom) therapy on asthma symptoms and pulmonary function in asthmatics with gastroesoph- ageal reflux. METHODS: We selected 198 asthmatics with gastroesophageal reflux diagnosed by 24-h esophageal pH monitoring to receive Ome 20 mg twice daily and Dom 10 mg three times daily or placebo for 16 wk (1:1 double-blind randomization). Spirometry was done at baseline and af- ter 16 wk of treatment. The primary outcome measures were: mean daily daytime and nighttime asthma symp- tom scores. Mean daily reflux symptom scores, albuterol use as rescue medication (number of puffs), daytime and nighttime peak expiratory flow rate (PEFR), postbroncho- dilator forced expiratory volume in 1 second (FEV1) and postbronchodilator forced vital capacity (FVC) were secondary outcome measures. RESULTS: Comparison of mean change from baseline between antireflux therapy and placebo groups revealed significant reduction in daytime asthma symptom score (17.4% vs 8.9%), nighttime asthma symptom score (19.6% vs 5.4%), reflux symptom score (8.7% vs 1.6%) and rescue medication use (23.2% vs 3.1%) after antire- flux therapy compared to mean change in placebo group (P < 0.001). There was significant improvement in morn- ing PEFR (7.9% vs 0.2%), evening PEFR (9.8% vs 0.5%), FEV1 (11.1% vs 3.78%) and FVC (9.3% vs 1.52%) in the antireflux therapy group compared to placebo on compar-ing the mean change from baseline after 16 wk (P < 0.01).Bhavneesh Sharma Manisha Sharma Mradul Kumar Daga Gopal Krishan Sachdev Elliott Bondi 2007World Journal of Gastroenterology2007,13,11:5
3Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels,and their responses to an inflammatory stimulus显示文摘Sharman KG Sharman EH Yang E Bondy SC 2002Neurobiol Aging2002,23,4:2
4IMMUNOMODULATION BY FUNGAL TOXINS显示文摘Genevieve S. Bondy James J. Pestka 2000Journal of Toxicology and Environmental Health, Part B2000,,2:2
5Teaching Teams: Creating the Context for Faculty Action Research显示文摘Elizabeth Bondy Dorene Ross 1998Innovative Higher Education1998,,3:2
6Heavy cycles in weighted graphs显示文摘Bondy J A Broersma H J Heuvel J van den 2002Discuss Math Graph Theory2002,22,:1
7The somatomedin hypothesis: 2001显示文摘Le Roith D Bondy C Yakar S 2001Endocr Rev2001,22,1:1
8Immunomodulation by fungal toxins显示文摘Bondy G S Pestka J J 2000J Toxicol Env Health Part B2000,3,2:1
9Androgens and mam- mary growth and neoplasia 显示文摘Dimitrakakis C Zhou J Bondy CA 2002Fertil Steril2002,77,4:1
10Particulate Matter in Polluted Air May Increase Biomarkers of Inflammation in Mouse Brain显示文摘A. Campbell M. Oldham A. Becaria S.C. Bondy D. Meacher C. Sioutas C. Misra L.B. Mendez M. Kleinman 2004Neurotoxicology2004,,1:1
11The somatomedin hypothesis: 2001显示文摘LE ROITH D BONDY C YAKAR S 2001Endocrine Reviews2001,22,1:1
12Inhibition of early upstream events in prodromal Mzheimer' s disease by use of targeted antioxidants 显示文摘Prasad KN Bondy SC 2014Curr Aging Sei2014,7,2:1
13Graph theory with application 显示文摘Bondy J Murty U 1976North - Holland1976,,:1
14Influence of feeder layer type on the efficiency of isolation of porcine embryo-derived cell lines显示文摘PIEDRAHITA J A AMDERSON G B BONDY R 1990Theriogenology1990,34,5:1
15Immunomodulation by fungal toxin显示文摘 Pestka J J 2000Toxicol Environ Health B Crit Rev2000,3,:1
16Issues in prenatal counselingand diagnosis in Turner Syndrome显示文摘Loscalzo M L Bondy C A Biesecker B 2006Int Congr Ser2006,1298,:1
17Still the most popular source of van der Waals ra- dii 显示文摘BONDI A 1964J Phys Chem1964,68,:1
18Amide based receptors for anions显示文摘Bondy C R Loeb S J 2003Coord Chem 尺你2003,240,12:1
19Contrasting molecular pathology of colorectal carcinoma in Egypatian and Western patients显示文摘Soliman A S Bondy M L EI-Badawy S A 2001Br J Cancer2001,85,7:1
20Detection of human cytomegalovirus in different histological types of gliomas 显示文摘Scheurer ME Bondy ML Aldape KD 2008Acta Neuropathol2008,116,1:1
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