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| 1 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 2 | Development of retinol-binding protein 4 immunocolloidal gold fast test strip using high-sensitivity monoclonal antibodies generated by DNA immunization显示文摘DNA 免疫是为高亲密关系的 monoclonal 抗体产生的一个有效方法。这里,我们对松香油绑定蛋白质 4 描述几高质量的 monoclonal 抗体(mAbs ) 的产生(RBP4 ) ,为肾反常和机能障碍的一个重要标记,与 DNA 的一个联合方法, priming 和蛋白质增加。产生的 mAbs 能与高敏感并且用这些 mAbs 绑在 RBP4,一块 immunocolloidal 金牌快测试长带被构造。长带能交上结果 < 5 min 并且与大约 1 ng/ml 的察觉限制是很敏感的。小规模的临床的测试表明这脱衣的结果根据在市场上当前可得到的一个标记酶的 immunosorbent 试金工具包的好。因而,它能为在诊所的更方便、更快的 RBP4 决心是有用的。 | Chao Bian Fang Zhang Feng Wang Zhiyang Ling Min Luo Hongqiang Wu Yizhuo Sun Junhui Li B ingnan Li Jingyan Zhu Linna Tang Yanyan Zhou Qunfang Shi Yongyong Ji Lin Tian Guomei Lin Yu Fan Niansong Wang Bing Sun | 2010 | Acta Biochimica et Biophysica Sinica2010，42，12： | 2 |
| 3 | Robust fixture configuration design for sheet metal assembly with laser welding显示文摘 | Li Bing Shiu B W Lau K J | 2003 | Journal of Manufacturing Science and Engineering2003，125，1： | 1 |
| 4 | Recursive estimation based on the equality-constrained optimization for intersection origin-destination matrices 显示文摘 | LI Bai - bing Moor B D | 1999 | Transportation Research1999，33，3： | 1 |
| 5 | An Intelligent Admission Control Scheme for Next Generation Wireless Systems using Distributed Genetic Algorithms显示文摘 | D Karabudak C C Huang B Bing | 2004 | IEEE communications society2004，3，： | 1 |
| 6 | Study of fault ride-through for DFIG based wind turbines 显示文摘 | Bing X Fox B Flylnn D | 2004 | IEEE Trans on Electric Utility Deregulation2004，1，5： | 1 |
| 7 | Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt 显示文摘 | Xing B Xin T Hunter RL Bing G | 2008 | J Neuroinflammation2008，5，： | 1 |
| 8 | Microbubble dynamics visualized in the intact capillary circulation 显示文摘 | Feinstein S B Shah P M Bing R J | 1984 | J Am Coil Cardiol1984，4，3： | 1 |
| 9 | In vitro susceptibilities to and bactericidal activities of garenoxacin(BMS-284756)and other antimicrobial agents against human mycoplasmas and ureaplasmas显示文摘 | Waites K B Crabb D M Bing X | 2003 | Antimicrob Agents Chemother2003，47，1： | 1 |
| 10 | Endothelium - dependent vascular effects of pycnogenol 显示文摘 | FITZPATRICK D F BING B ROHDEWALD P | 1998 | Cardiovasc Pharmacol1998，32，4： | 1 |
| 11 | A shrunken-2 transgene increases maize yield by acting in maternal tissues to increase the frequency of seed development显示文摘 | Hannah LC Futch B Bing J | 2012 | Plant Cell2012，24，： | 1 |
| 12 | Neuroprotection with pioglitazone against LPS insult on dopaminergic neurons may be associated with its inhibition of NF-kappaB and JNK activation and suppression of COX-2 activity显示文摘 | Xing B Liu M Bing G | 2007 | J Neuroimmunol2007，192，12： | 1 |
| 13 | Preparation and characterization of nano scaled poly( Vinyl Alcohol) fibers via electrospinning显示文摘 | BING B KIM H Y LEE S C | 2002 | Fibers and Polymers2002，3，2： | 1 |
| 14 | Synthesis of cerium-doped MCM-41for ozonation of p-chlorobenzoic acid in aqueous solution 显示文摘 | Bing J Li L Lan B | 2012 | Applied Catalysis B :Environmental2012，，： | 1 |
| 15 | Endothelium dependent vascular effects of Pycnogenol显示文摘 | Fitzpatrick DF Bing B Rohdewald P | 1998 | J Cardiovasc Pharmacol1998，32，4： | 1 |
| 16 | An Intelligent Admission Control Scheme for Next Generation Wireless Systems using Distributed Genetic Algorithms显示文摘 | KARABUDAK D HUANG CC BING B | 2004 | IEEE communications society2004，13，： | 1 |
| 17 | Harmonic power detection in wideband cognitive radios显示文摘 | Sheikh F Masud S Bing B | 2009 | IETSignal Processing2009，3，1： | 1 |
| 18 | Synthesis of cerium-doped MCM-41 for ozonation of p-chlorobenzoic acid in aqueous solution显示文摘 | BING J LI L LAN B | 2012 | Applied Catalysis B: Environmental2012，，： | 1 |
| 19 | Psychiatric disorders,and drug use among human immunodeciency virus infected adults in the United States显示文摘 | Bing E urnam A B ongshore D L | 2001 | Arch Gen Psychiatry2001，58，： | 1 |
| 20 | Adjuvant action of Chenopodium quinoa saponins on the induction of anti- body responses to intragastric and intranasal administered antigens in mice 显示文摘 | ESTRADA A LI Bing LAARVELD B | 1998 | Comp Immunol Microbiol Infect Dis1998，21，3： | 1 |
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