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| 1 | Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner显示文摘遇到 hypoxic 应力的房间由 downregulating 保存资源和精力蛋白质合成。这里我们 demonstratethat 在这回答的一机制是最高的 mRNAs 的翻译压抑编码 translationalapparatus 的部件。规定的这个模式包含 TSC 和 Rheb,当 Rheb 的 TSC1 或 TSC2 或 overexpression 的大美人在剥夺氧的房间救了最高的 mRNA 翻译。导致压力的翻译 repressionof 这些 mRNAs 密切与 4E-BP 的 hypophosphorylated 状态相关,一个翻译抑压者。然而, seriesof 4E-BP loss-of-function 和 gain-of-function 实验在氧或生长因素剥夺下面反驳在 phosphorylation statusof 4E-BP 和最高的 mRNAs 的翻译压抑之间的一种 cause-and-effect 关系。而且,血缺氧的 repressiveeffect 类似于由 Torin 1,而是更多 pronouncedthan 猛禽或 rictor 大美人由 mTOR 活动的有效抑制到达了那。同样,猛禽或 rictor 的缺乏它温和地 downregulated TOPmRNAs 的基础翻译效率,没能压制最高的 mRNAs 的调停氧的翻译激活。最后, TIA-1 和 TIAR co 击倒,二 RNA 有约束力的蛋白质以前在氨基的酸饥饿的房间在最高的 mRNAs 的翻译压抑含有, failedto 在另外的压力条件下面减轻最高的 mRNA 翻译。因此,近似翻译管理者 ofTOP mRNAs 的性质留下逃犯。 | Rachel Miloslavski Elad Cohen Adam Avraham Yifat I luz Zvi Hayouka Judith Kasir Rajini Mudhasani Stephen N. Jones Nadine Cybulski Markus A. Ruegg Ola Larsson Valentina Gandin Arjuna Rajakumar Ivan Topisirovic Oded Meyuhas | 2014 | Journal of Molecular Cell Biology2014，8，3： | 3 |
| 2 | Nutritional status, cognition, and survival: A new role for lep- tin and AMP kinase显示文摘 | Dagon Y Avraham Y Magen I | 2005 | J Biol Chem2005，280，42： | 1 |
| 3 | Enhanced charge efficiency in capacitive deionization achieved by surface-treated electrodes and by means of a third electrode 显示文摘 | Cohen I Avraham E Noked M | 2011 | The Journal of Physical Chemistry C2011，115，19： | 1 |
| 4 | Galectin-3 Stimulates Cell Proliferation显示文摘 | Hidenori I Shiro A Avraham R | 1998 | Exper Cell Res1998，245，： | 1 |
| 5 | Pre-emptive effect of ibupro-fen versus placebo on pain relief and success rates of medical abor-tion:A double-blind,randomized,controlled study显示文摘 | Avraham S Gat I Duvdevani NR | 2012 | Fertility andSterility2012，97，3： | 1 |
| 6 | Methods for the study of protein-protein interactions in cancer cell biology 显示文摘 | PRICE D PARK I AVRAHAM H | 2003 | Methods Mol Biol2003，218，40： | 1 |
| 7 | VEGF-induced adult neovascularization : recruitment, retention, and role of accessory cells 显示文摘 | Grunewald M Avraham I Dor Y | 2006 | Cell2006，124，1： | 1 |
| 8 | VEGF-induced adult neovascularization:recruitment,retention,and role of accessory cells显示文摘 | Avraham I Dor Y | 2006 | Cell2006，124，1： | 1 |
| 9 | Effect of sulbactam on infections caused by imipenem-resistant Acinetobacter calcoaceticus biotype anitratus 显示文摘 | Urban C Go E Mariano N Berger BJ Avraham I Rubin D Rahal JJ | 1993 | J Infect Dis1993，167，2： | 1 |
| 10 | Coaxial tubular solar collector constructed from polymeric materials:an experimental and transient simulation study显示文摘 | Avraham I K Efim G E Gerd W | 2003 | Energy Conversion and Management2003，44，16： | 1 |
| 11 | VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells 显示文摘 | Grunewald M Avraham I Dot Y | 2006 | Cell2006，124，1： | 1 |
| 12 | Nutritional status,cognition and survival- a new role for leptin and AMPK 显示文摘 | Dagon Y Avraham Y Magen I | 2005 | J Biol Chem2005，280，42： | 1 |
| 13 | VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells显示文摘 | Grunewald M Avraham I Dor Y | 2006 | Cell2006，124，1： | 1 |
| 14 | High-order finite element methods for acoustic problems显示文摘 | HARARI I AVRAHAM D | 1997 | Journal of Computational Acoustics1997，5，： | 1 |
| 15 | Hemobilia due to hepatic artery aneurysm as the presenting sign of fibro-muscular dysplasia显示文摘Fibro-muscular dysplasia(FMD)is a rare but well documented disease with multiple arterial aneurysms. The patients,usually women,present with various clinical manifestations according to the specific arteries that are affected.Typical findings are aneurysmatic dilatations of medium-sized arteries.The renal and the internal carotid arteries are most frequently affected, but other anatomical sites might be affected too.The typical angiographic picture is that of a'string of beads'. Common histological features are additionally described. Here we present a case of a 47-year-old woman,who was hospitalized due to intractable abdominal pain.A routine work-up revealed a liver mass near the portal vein.Before a definite diagnosis was reached,the patient developed massive upper gastrointestinal bleeding.In order to control the hemorrhage,celiac angiography was performed revealing features of FMD in several arteries, including large aneurysms of the hepatic artery.Active bleeding from one of these aneurysms into the biliary tree indicated selective embolization of the hepatic artery.The immediate results were satisfactory,and the 5 years follow-up revealed absence of any clinical symptoms. | Noam Shussman Yair Edden Yoav Mintz Anthony Verstandig Avraham I Rivkind | 2008 | World Journal of Gastroenterology2008，14，11： | 1 |
| 16 | VEGF induced adult neovascularization:recruitment,retention,and role of accessory cells显示文摘 | Grunewald M Avraham I Dor Y | | 0，，01： | 1 |
| 17 | Effect of methylene blue on resuscitation after haemorrhagic shock 显示文摘 | Jeroukhimov I Weinbroum A Ben- Avraham R | 2001 | Eur J Surg2001，167，10： | 1 |
| 18 | VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells 显示文摘 | Grunewald M Avraham I Dor Y | 2006 | J Ce112006，124，1： | 1 |
| 19 | VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells 显示文摘 | GRUNEWALD M AVRAHAM I DOR Y | 2006 | Cell2006，24，1： | 1 |
| 20 | VEGF-induced adult neovascularization: recruitment, retention, and role of accessory Cells显示文摘 | Grunewald M Avraham I Dor Y | 2006 | Cell2006，124，1： | 1 |
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