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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 3 | The role of hypofractionation radiotherapy for diffuse intrinsic brainstem glioma in children: a pilot study显示文摘 | Janssens GO Gidding CE Van Lindert E J Oldenburger FR Erasmus CE Schouten-Meeteren A Y Kaanders JH | 2009 | 中国神经肿瘤杂志2009，7，3： | 8 |
| 4 | Ecologicallimits to plant phenotypic plasticity 显示文摘 | Valladares F Gianoli E Go mez J M | 2007 | NewPhytologist2007，176，4： | 1 |
| 5 | Flammability limit measurements for dusts in 20-L and 1 m3 vessels显示文摘 | Going J E Chatrathi K Cashdollar K L | 2000 | Journal ofLoss Prevention in the Process Industries2000，13，3： | 1 |
| 6 | Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness显示文摘 | Leaf D E Go ldfarb D S | 2007 | JApplPhysiol2007，102，4： | 1 |
| 7 | New product design using FDMS and FANP under fuzzy environment显示文摘 | GO ¨ NG O ¨ R Z KILIC E DELICE | | 0，，11： | 1 |
| 8 | Allelopathy and microclimatic modification of intercropping with marigold on tomato early blight disease development 显示文摘 | GO' MEZ R O ZAVALETA M E GONZA' LEZ H A | 2003 | Field Crops Research2003，83，： | 1 |
| 9 | The natural andartificial aging response of semi-solid metal processed alloy A356显示文摘 | MOLLER H GO VENDER G STUMPF W E | 2008 | Solid State Phenomena2008，，： | 1 |
| 10 | An- tagonistic changes between abscisic acid and gib- berellins in citrus fruits subjected to a series of different water conditions 显示文摘 | Mehouachi J Go mez-Cadenas A Primo-Millo E | 2005 | Plant Growth Regul2005，，24： | 1 |
| 11 | Clinical analgesic efficacy andside effects of dexmedetomidine in the early postoperative periodafter arthroscopic knee surgery显示文摘 | GO'MEZ-VA'ZQUEZ ME HERNA'NDEZ-SALAZAR E HER-NA'NDLEZ-JIME'NEZ A | 2007 | J Clin Anesth2007，19，： | 1 |
| 12 | Sentinel lymph node biopsy for breast cancer using methylene blue dye manifests a short learning curve among experienced surgeons : a prospective tabular cumulative sum (CUSUM) analysis 显示文摘 | East JM Valentine CS Kanchev E Blake GO | 2009 | BMC Surg2009，9，： | 1 |
| 13 | Maintenance strategy based on a multicriterion classification of equipments 显示文摘 | E'LIX C Go'mez de Leo'n Hijes JOSE Javier Ruiz Cartagena | 2006 | Reliability Engineering and System Safety2006，91，： | 1 |
| 14 | Chronickidney disease and prevalent atrial fibrillation : the ChronicRenal Insufficiency Cohort (CRIC) 显示文摘 | SOLIMAN E Z PRINEAS R J GO A S | 2010 | Am Heart J2010，159，6： | 1 |
| 15 | Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology显示文摘 | FARDELLA C E MOSSO L GO'MEZ-SA'NCHEZ C | 2000 | J Clin Endocrinol Metab2000，85，： | 1 |
| 16 | Ultrasound-guidcd soft catheter embryo transfer will improve pregnancy rates in xitro fertilization显示文摘 | Wood E G Batzer F Go K J | 2000 | Hum Reprod2000，15，1： | 1 |
| 17 | The antioxidant acticity of aqueous spinach extract:emical identification of active fractions显示文摘 | Bergman M Va rshavsky L Go ttlieb H E | 2001 | Phytochemistry2001，58，1： | 1 |
| 18 | C5a-dependent up-regulation in vivo of lung vascular P-selectin显示文摘 | Mulligan MS Schmid E Till GO | 1997 | Immunol1997，158，： | 1 |
| 19 | Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam 显示文摘 | Go E S Urban C Burns J | 1994 | Lancet1994，344，8933： | 1 |
| 20 | Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study显示文摘 | Go A S Hylek E M Phillips K A | 2001 | JAMA2001，285，18： | 1 |
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