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| 1 | A rare case of isolated castrate resistant bilateral testicular metastases in advanced prostate cancer显示文摘Testicular metastasis is rare with the prostate being the most common site of primary cancer.We report a case of a 72-year-old man with castration-resistant prostate cancer(CRPC)and known metastases to bone and lymph nodes,who developed bilateral painful swollen testes 3 years after the initial diagnosis of prostate cancer.He had first presented with lower urinary tract symptoms(LUTS)with suspicious findings on digital rectal examination of the prostate,and an elevated serum prostate specific antigen(PSA)level of 129 ng/mL.Transrectal prostate biopsy revealed Gleason 4þ5 adenocarcinoma.Radiological staging showed locally advanced prostate cancer with extensive metastases to bone and pelvic and retroperitoneal lymph nodes.He was given hormonal therapy for over 2 years until progression to CRPC.Six months later he developed painful bilateral testicular swellings,and serum markers for testicular germ cell cancer were normal.Bilateral orchiectomy was performed,showing metastatic prostate cancer(Gleason 4þ5)on histology.One month postoperatively his PSA level dropped to 0.1 ng/mL from a presurgery level of 6.24 ng/mL. | Jiarui Su Edwin Jonathan Aslim Hakan Aydin Puay Hoon Tan Henry Sun Sien Ho | 2018 | Asian Journal of Urology2018，5，2： | 2 |
| 2 | Cholesterol removal by some lactic acid bacteria that can be used as probiotic 显示文摘 | TOK E ASLIM B | 2010 | M icrobiol Immuno12010，54，5： | 1 |
| 3 | Cholesterol removal by some lactic acid bacteria that can be used as probiotic 显示文摘 | TOK E ASLIM B | 2010 | Microbiol & Immuno12010，54，5： | 1 |
| 4 | Protective effect of two edible mushrooms against oxidative cell damage and their phenolic composition显示文摘 | Feyza Oke Belma Aslim | 2011 | Food Chemistry2011，，3： | 1 |
| 5 | Cholesterol removal by some lactic acid bacteria that can be used as probiotic显示文摘 | Esra Tok Belma Aslim | 2010 | Microbiology and Immunology2010，，54： | 1 |
| 6 | Determination of the Bacteriocin-like Substances Produced by Some Lactic Acid Bacteria Isolated from Turkish Dairy Products显示文摘 | ASLIM B YUKSEKDAG Z N SAKIKAYA E | 2005 | LWT2005，38，： | 1 |
| 7 | Produc- tion of poly-13-hydroxybutyrate (PHB) and differentiation of putative Bacillus mutants strains by SDS-PAGE of total cell protein显示文摘 | Katircioglu H Aslim B Yttksekdao Z N | 2003 | African Journal of Biotechnology2003，2，6： | 1 |
| 8 | Antimicrobial and antioxidant activities of Russula delica Fr显示文摘 | YALTIRAK T ASLIM B OZTURK S | 2009 | Food and Chemical Toxicology2009，47，8： | 1 |
| 9 | Protective effect of two edible mushroomsagainstoxidative cell damage and their phenoliccomposition显示文摘 | Oke F Aslim B | 2011 | FoodChemt2011(128):613-6192011，2011，128： | 1 |
| 10 | Effects Of exopolysaccharide producingprobiotic strains On experimental colitis in rats显示文摘 | SENGU IN ASLIM B UCAR C | 2006 | Dis Colon Rectum2006，49，2： | 1 |
| 11 | Protective effect of two edible mushroomsagainst oxidative cell damage and their phenoliccomposition显示文摘 | Oke F Aslim B | 2011 | Food Chem2011，128，： | 1 |
| 12 | Cholesterol removal by some lactic acid bacteria that can be used as probiotic 显示文摘 | TOK E ASLIM B | 2010 | Micro- biology and Immunology2010，54，5： | 1 |
| 13 | Protective effect of two ediblemushrooms against oxidative cell damage and theirphenolic compositio显示文摘 | OKE F ASLIM B | 2011 | Food Chem2011，128，3： | 1 |
| 14 | Use of the anterolateral thigh and vertical rectus abdominis musculocutaneous flaps as utility flaps in reconstructing large groin defects 显示文摘 | Aslim E J Rasheed MZ Lin F | 2014 | Arch Plast Surg2014，41，5： | 1 |
| 15 | Multiparametric MRI reporting using Prostate Imaging Reporting and Data System version 2.0 (PI-RADSv2) retains clinical efficacy in a predominantly post-biopsy patient population显示文摘Objective:To evaluate the efficacy of multiparametric magnetic resonance imaging(mp-MRI)using Prostate Imaging Reporting and Data System version 2.0(PI-RADSv2)definitions in detecting organ-confined prostate cancer.Methods:All patients who underwent radical prostatectomy between January 1,2014 and December 30,2014 were identified.All underwent mp-MRI within 180 days before surgery.Those with prior pelvic irradiation or androgen deprivation therapy were excluded.Fully embedded,whole-mount histopathology was centrally reviewed and correlated with imaging for tumour location,Gleason score(GS)and stage.Results:There were 39 patients included,of which 35(90%)had mp-MRI done post-biopsy.A total of 93 cancer foci were identified on whole-mount pathology,of which mp-MRI detected 63(68%).Of those detected by mp-MRI,14 were PI-RADS 3(n=6 for GS 6,n=8 for GS 7,no GS≥8)and 49 were PI-RADS 4e5(nZ7 for GS 6,nZ33 for GS 7,and nZ9 for GS≥8).There were 30(32%)cancer foci missed by mp-MRI(n=15 for GS 6,n=13 for GS 7 and n=2 for GS≥8).A lesion classified as PI-RADS 4e5 predicted a higher grade cancer on pathology as compared to PI-RADS 3(for GS 7 lesions,odds ratio[OR]=3.53,95%CI:0.93e13.45,p=0.064).The mp-MRI size detection limit was 20 mm2 and 100 mm2 for 50%and 75%probability of cancer,respectively.In associating with radiological and pathologic stage,the weighted Kappa value was 0.69(p<0.0001).The sensitivity and positive predictive values for this study were 68%(95%CI:57%e77%)and 78%(95%CI:67%e86%),respectively.Conclusion:In this predominantly post-biopsy cohort,mp-MRI using PI-RADSv2 reporting has a reasonably high diagnostic accuracy in detecting clinically significant prostate cancer. | Edwin Jonathan Aslim Yan Mee Law Puay Hoon Tan John Carson Allen Jr Lionel Tim-Ee Cheng Viswanath Anand Chidambaram Li Yan Khor Benjamin Yongcheng Tan Ernest Wencong Eu Christopher Wai Sam Cheng John Shyi Peng Yuen Henry Sun Sien Ho Lui Shiong Lee | 2019 | Asian Journal of Urology2019，6，3： | 1 |
| 16 | Determinationof the bacteriocin-like substances produced by some lacticacid bacteria isolated from Turkish dairy products 显示文摘 | Aslim B Yuksekdag Z Sarikaya E | 2005 | LWT - Food Science and Technology2005，38，6： | 1 |
| 17 | Protective effect of two edible mush-rooms against oxidative cell damage and their phenolic composition显示文摘 | Oke F Aslim B | 2011 | Food Chemistry2011，128，3： | 1 |
| 18 | Cholesterol removal by some lactic acid bacteria that can be used as probiotic 显示文摘 | TOK E ASLIM B | 2010 | Microbiology and Immunology2010，54，： | 1 |
| 19 | Enhanced crude oil biodegradation and rhamnolipid production by Pseudomonas stutzeri strain G11 in the presence of Twcen-80 and Triton X-100显示文摘 | Celik G Y Aslim B Beyatli Y | 2008 | Journal of Environmental Biology2008，29，6： | 1 |
| 20 | Antibiotic resistance and plasmid DNA contents of Streptococcus therrnophilus strains isolated from Turkish yogurts 显示文摘 | Aslim B Beyatli Y | 2004 | Turk J Vet Anim Sci2004，28，： | 1 |
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