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| 1 | 基于随机决策森林的高压电缆局部放电模式识别显示文摘不同类型的高压电缆局部放电(简称局放)模式识别是该领域的难题。部分电缆局放类型之间相似度较大,识别困难。针对该问题,文中提出了一种基于随机决策森林(RF)的高压电缆局放模式识别方法。首先,制作了5种高压电缆人工缺陷,结合IEC 60270—2015系统和高频电流互感器(HFCT)进行实验,获取局放数据,并进行局放特征提取。其次,介绍了随机森林算法的原理和基于随机森林的高压电缆局放模式识别流程。最后,基于实验所得数据开展了局放模式识别方法有效性验证,确定了随机森林每个节点处特征子集中特征个数、节点分裂规则、树的棵数3个参数,并与传统的决策树、BP神经网络和支持向量机(SVM)3种方法进行比较。结果显示,与上述3种方法相比,随机森林算法对高相似度局放识别能力更强。 | 刘文浩 吴毅江 李文泽 王洪雨 Ashfaque Ahmed Bhatti 彭小圣 何顺姬 | 2022 | 高压电器2022，58，6： | 10 |
| 2 | Acquired pMHC I Complexes Greatly Enhance CD4^+ Th Cell's Stimulatory Effect on CD8^+ T Cell-Mediated Diabetes in Transgenic RIP-mOVA Mice显示文摘CD4+ helper T (Th) cells play pivotal roles in induction of CD8+ CTL immunity. However, the mechanism of CD4+ T cell help delivery to CD8+ T cells in vivo is still elusive. In this study, we used ovalbumin (OVA)-pulsed dendritic cells (DCOVA) to activate OT-II mouse CD4+ T cells, and then studied the help effect of these CD4+ T cells on CD8+ cytotoxic T lymphocyte (CTL) responses. We also examined CTL mediated islet β cell destruction which led to diabetes in wild-type C57BL/6 mice and transgenic rat insulin promoter (RIP)-mOVA mice expressing β cell antigen OVA with self OVA-specific tolerance, respectively. In adoptive transfer experiments, we demonstrated that help, in the form of peptide/major histocompatibility complex (pMHC) I acquired from DCOVA by DCOVA activation, was required for induction of OVA-specific CTL responses in C57BL/6 mice. However, in combination with TCR transgenic OT-I mouse CD8+ T cells, the tolerogenic dosage of CD4+ Th cells with acquired pMHC I, but not CD4+ (Kb-/-) Th cells without acquired pMHC I were able to cause diabetes in 8/10 (80%) RIP-mOVA mice. This study thus expands the current knowledge in T cell-mediated autoimmunity and provides insight into the nature of CD4+ T cell-mediated help in CD8+ CTL induction. | Khawaja Ashfaque Ahmed Yufeng Xie Xueshu Zhang Jim Xiang | 2008 | Cellular & Molecular Immunology2008，5，6： | 6 |
| 3 | Intercellular Trogocytosis Plays an Important Role in Modulation of Immune Responses显示文摘Intercellular communication is an important means of molecular information transfer through exchange of membrane proteins from cells to cells. Advent of the latest analytical and imaging tools has allowed us to enhance our understanding of the cellular communication through the intercellular exchange of intact membrane patches,also called trogocytosis,which is a ubiquitous phenomenon. Immune responses against pathogens or any foreign antigens require fine immune regulation,where cellular communications are mediated by either soluble or cell surface molecules. It has been demonstrated that the membrane molecule transfer between immune cells such as dendritic and T cells can be derived through internalization/recycling pathway,dissociation-associated pathway,uptake of exosomes and membrane nanotube formations. Recent evidence implicates the trogocytosis as an important mechanism of the immune system to modulate immune responses. Exchange of membrane molecules/ antigens between immune cells has been observed for a long time,but the mechanisms and functional consequences of these transfers remain unclear. In this review,we discuss the possible mechanisms of trogocytosis and its physiological relevance to immune system,with special reference to T cells and the stimulatory or suppressive immune responses derived from T cells with acquired dendritic cell membrane molecules. | Khawaja Ashfaque Ahmed Manjunatha Ankathatti Munegowda Jim Xiang | 2008 | Cellular & Molecular Immunology2008，5，4： | 6 |
| 4 | 基于可变噪音的高压电缆局部放电样本扩充显示文摘高压电缆局部放电样本数量对模式识别精度有较大影响,样本数量不足,模型难以得到充分训练,从而影响识别精度,对局部放电样本进行扩充可以有效解决该难题,对此,提出基于可变噪音的高压电缆局部放电样本扩充方法。首先,构建5种高压电缆典型缺陷并进行加压测试,获取局部放电原始数据;然后,介绍基于可变噪音的局部放电样本扩充原理;最后,采用随机森林、支持向量机、逻辑回归3种方法来验证所提方法的可行性。结果表明:基于可变噪音的局部放电样本扩充方法可以提高局部放电模式识别精度;在噪音水平为0.01时,对随机森林模型的识别精度提升了3.15%,提升效果最好。 | 刘文浩 李文泽 王洪雨 吴毅江 王干军 Ashfaque Ahmed Bhatti 彭小圣 | 2020 | 广东电力2020，33，9： | 3 |
| 5 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh 显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B M | 2010 | Nature Geoscience2010，3，1： | 1 |
| 6 | Effect of garlic extract on haematobiochemical changes in Eimeria tenella infected broiler chicken显示文摘 | Dar S A Verma P Ashfaque M | 2014 | National Academy Science Letters2014，37，4： | 1 |
| 7 | Phenotypic and molecular detection of CTX-M-β-Lactamases produced by escherichia coti and klebsielta spp 显示文摘 | Johann D D Ashfaque H Nancy D H | 2004 | J Clin Microbiot2004，42，12： | 1 |
| 8 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh 显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B | 2010 | Nature Geoscience2010，3，1： | 1 |
| 9 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B M | 2009 | Nature Geoscience2009，3，1： | 1 |
| 10 | Groundwater Dynamics and Arsenic Contamination in Bangladesh显示文摘 | HARVEY C F ASHFAQUE K N YU W | 2006 | Chemical Geology2006，228，123： | 1 |
| 11 | Embelin reduces cutaneous TNF-α level and ameliorates skin edema in acute and chronic model of skin inflammation in mice显示文摘 | G. Kalyan Kumar R. Dhamotharan Nagaraj M. Kulkarni Mahamad Yunnus A. Mahat J. Gunasekaran Mohammad Ashfaque | 2011 | European Journal of Pharmacology2011，，1： | 1 |
| 12 | Erlotinib accumulation in brain metastases from non-small cell lung cancer:visualization by positron emission tomography in a patient harboring a mutation in the epidermal growth factor receptor显示文摘 | Britta W Michael W Ashfaque M | | 0，，07： | 1 |
| 13 | Thermal-comfort analysis and simulation for various low-energy cooling-techn- ologies applied to an office building in a subtropical climate 显示文摘 | Ashfaque A C Rasul M G Khan M M K | 2008 | Applied Energy2008，85，6： | 1 |
| 14 | Anthropegenic influences on groundwater arsenic concentrations in Bangladesh显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B | | 0，，01： | 1 |
| 15 | Osteoporosis in men 显示文摘 | Rao SS Budhwar N Ashfaque A | 2010 | Am Fam Physician2010，82，5： | 1 |
| 16 | Association of blood group a with increased risk of coronary heart disease in the Pakistani population显示文摘 | Wazirali H Ashfaque RA Joachim W | 2005 | Pak J Physiol2005，1，12： | 1 |
| 17 | An Analysis of the Indoor Air Quality and Mould Growthin a Multi-zone Building显示文摘 | Ashfaque AC Rasul MG Khan MMK | 2009 | Water Air Soil Pollut:Focus2009，10，1： | 1 |
| 18 | Groundwater dynamics and arsenic contamination in Bangladesh显示文摘 | Harvey C F Ashfaque K N Yu W | | 0，，1： | 1 |
| 19 | Phe- notypic and Molecular Detection of CTX - M - β- Lactamases Pro- duced byEscher/ehia coli and Klebsiella spp显示文摘 | Hanson Johann D D itout Ashfaque Hossain Nancy D | 2004 | Clin Microbiol2004，42，12： | 1 |
| 20 | 男性骨质疏松症显示文摘男性骨质疏松症是一个重要但常常被忽视的问题。治疗骨质疏松症应根据临床评估、诊断检查、骨折风险评估和骨矿物质密度测量。 | SHOBHA S. RAO NITIN BUDHWAR AMBREEN ASHFAQUE 刘思 孙湛博 王大路(译) | 2011 | 中国实用乡村医生杂志2011，18，4： | 0 |
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