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| 1 | Acute upper gastrointestinal bleeding in octοgenarians:Clinical outcome and factors related to mortality显示文摘AIM: To evaluate the aetiology, clinical outcome and factors related to mortality of acute upper gastrointestinal bleeding (AUGIB) in octogenarians. METHODS: We reviewed the records of all patients over 65 years old who were hospitalised with AUGIB in two hospitals from January 2006 to December of 2006. Patients were divided into two groups: Group A (65-80 years old) and Group B (> 80 years old). RESULTS: Four hundred and sixteen patients over 65 years of age were hospitalized because of AUGIB. Group A included 269 patients and Group B 147 patients. Co-morbidity was more common in octogenarians (P = 0.04). The main cause of bleeding was peptic ulcer in both groups. Rebleeding and emergency surgery were uncommon in octogenarians and not different from those in younger patients. In-hospital complications were more common in octogenarians (P = 0.05) and more patients died in the group of octogenarians compared to the younger age group (P = 0.02). Inability to perform endoscopic examination (P = 0.002), presence of high risk for rebleeding stigmata (P = 0.004), urea on admission (P = 0.036), rebleeding (P = 0.004) and presenceof severe co-morbidity (P < 0.0001) were related to mortality. In multivariate analysis, only the presence of severe co-morbidity was independently related to mortality (P = 0.032). CONCLUSION: While rebleeding and emergency surgery rates are relatively low in octogenarians with AUGIB, the presence of severe co-morbidity is the main factor of adverse outcome. | George J Theocharis Vassiliki Arvaniti Stelios F Assimakopoulos Konstantinos C Thomopoulos Vassilis Xourgias Irini Mylonakou Vassiliki N Nikolopoulou | 2008 | World Journal of Gastroenterology2008，14，25： | 15 |
| 2 | Acute upper gastrointestinal bleeding in operated stomach: Outcome of 105 cases显示文摘AIM: To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past.METHODS: The causes and clinical outcome were compared between 105 patients with AUGB and a history of gastric surgery, and 608 patients with AUGB but without a history of gastric surgery.RESULTS: Patients who underwent gastric surgery in the past were older (mean age: 68.1±11.7 years vs 62.8±17.8 years, P= 0.001), and the most common cause of bleeding was marginal ulcer in 63 patients (60%). No identifiable source of bleeding could be found in 22 patients (20.9%) compared to 42/608 (6.9%) in patients without a history of gastric surgery (P = 0.003). Endoscopic hemostasis was permanently successful in 26 out of 35 patients (74.3%) with peptic ulcers and active bleeding or non-bleeding visible vessel. Nine patients (8.6%) were operated due to continuing or recurrent bleeding,compared to 23/608 (3.8%) in the group of patients without gastric surgery in the past (P= 0.028). Especially in peptic ulcer bleeding patients, emergency surgery was more common in the group of patients with gastric surgery in the past [9/73 (12.3%) vs 19/360 (5.3%), P = 0.025].Moreover surgically treated patients in the past required more blood transfusion (3.3±4.0 vs 1.5±1.7, P = 0.0001) and longer hospitalization time (8.6±4.0 vs 6.9±4.9 d,P = 0.001) than patients without a history of gastric surgery. Mortality was not different between the two groups [4/105 (3.8%) vs 19/608 (3.1%)].CONCLUSION: Upper gastrointestinal bleeding seems to be more severe in surgically treated patients than in non-operated patients. | Vassiliki N Nikolopoulou Konstantinos C Thomopoulos George I Theocharis Vassiliki A Arvaniti Constantine E Vagianos | 2005 | World Journal of Gastroenterology2005，11，29： | 9 |
| 3 | Wireless capsule endoscopy in the investigation of patients with chronic renal failure and obscure gastrointestinal bleeding (preliminary data)显示文摘瞄准:在小肠(SB ) 的察觉调查无线的囊内视镜检查法(WCE ) 的角色在有长期的肾衰竭(CRF ) 并且阴暗流血的病人的病理。方法:有阴暗流血的连续 CRF 病人有希望地被学习。有正常肾的功能并且阴暗流血的病人,与 WCE 在一样的时期期间调查了,被用于结果的解释。结果:十七个 CRF 病人(11 公开, 6 玄术流血) 并且 51 个病人(33 公开, 18 玄术流血) 与正常,肾的功能在这研究被注册。积极 SB 调查结果在 70.6% CRF 病人被检测(P <
0.05 ) 。SB angiodysplasia 在 47% CRF 病人被识别。Univariate 逻辑回归为 angiodysplasia 作为一个重要预兆的因素揭示了 CRF (P <
0.05 ) 。治疗学的措施与积极调查结果在 66% 病人被承担。结论:根据我们的初步的结果, SB angiodysplasia 与阴暗流血在 CRF 病人之中在增加的流行被发现。WCE 在胃肠的病理的诊断并且在计划适当治疗学的干预是有用的并且因此,应该在这组病人的病情的检查被包括。 | Stephanos Karagiannis Spyros Goulas Georgios Kosmadakis Petros Galanis Dimitrios Arvanitis John Boletis Evangelos Georgiou Christos Mavrogiannis | 2006 | World Journal of Gastroenterology2006，12，32： | 8 |
| 4 | Renal failure and cirrhosis: A systematic review of mortality and prognosis显示文摘 | Giuseppe Fede Gennaro D’Amico Vasiliki Arvaniti Emmanuel Tsochatzis Giacomo Germani Dimosthenis Georgiadis Alberto Morabito Andrew Kenneth Burroughs | 2011 | Journal of Hepatology2011，，4： | 4 |
| 5 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer显示文摘 | Schachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004，431，5： | 1 |
| 6 | Multiple fixed doese of 'Seroquel' (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo 显示文摘 | Arvanitis LA Miller BC | 1997 | Biol Psychiatry1997，42，3： | 1 |
| 7 | Epidemiology of Pseudomonas oeruginosa and risk factors for carriage acquisition in an intensive care unit 显示文摘 | Thuong M Arvaniti K Ruimy R | 2003 | J Hosp Infect2003，53，4： | 1 |
| 8 | Conjugated bilirubin: A better indiCator of impaired hepatobiliary excretion than direct bilirubin 显示文摘 | Arvan D Shirey T L | 1985 | Ann Clin Lab Sci1985，15，3： | 1 |
| 9 | The Seroquel trials study group Multiple fixed doses of 'Seroquel'(quatrian) in patients with acute exacerbation of schizophrenia: a compares on with halopendol and plaeebo显示文摘 | Arvanitis LA Miller BG | 1997 | Biol Psychiatry1997，42，： | 1 |
| 10 | Quetiapine in the treatment of schizophrenia patient显示文摘 | Arvan LA Kandel ER | 1997 | Biol Psychiatry1997，7，6： | 1 |
| 11 | Pharmacokinetics to liability and clinical effectiveness of quetial:fine fumarate: an open--label trial in adolescents with psychotic disorders显示文摘 | Meonville BJ Arvanitis LA Thyrun PT | 2000 | J Clin Psychiatry2000，61，： | 1 |
| 12 | HealthAgents: distributed multi-agent brain tumor diagnosis and?prognosis显示文摘 | Horacio González-Vélez Mariola Mier Margarida Julià-Sapé Theodoros N. Arvanitis Juan M. García-Gómez Montserrat Robles Paul H. Lewis Srinandan Dasmahapatra David Dupplaw Andrew Peet Carles Arús Bernardo Celda Sabine Huffel Magí Lluch-Ariet | 2009 | Applied Intelligence2009，，3： | 1 |
| 13 | Quetiapine,a novel antipsychotics:experience in elderly patients with psychotic disorders显示文摘 | Mcmanus DQ Arvanitis LA Kowalcyk BB | 1999 | J Clin Psychiatry1999，60，5： | 1 |
| 14 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer显示文摘 | SHACHAF C M KOPELMAN A M ARVANITIS C | 2004 | Nature2004，431，7012： | 1 |
| 15 | Com- parison of Oligon catheters and chlorhexidine-impreg- nated sponges with standard multilumen centralvenous catheters for prevention of associated colonization and infections in intensive care unit patients: a multicenter, randomized, controlled study显示文摘 | Arvaniti K Lathyris D Clouva-Molyvdas P | 2012 | Crit Care Med2012，40，2： | 1 |
| 16 | Description of the new I1011 beamline for magnetic measurements using synchrotron radiation at MAX-lab显示文摘 | I A Kowalik G ?hrwall B N Jensen R Sankari E Wallén U Johansson O Karis D Arvanitis | 2010 | Journal of Physics: Conference Series2010，，1： | 1 |
| 17 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular carcinoma显示文摘 | Shachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004，431，： | 1 |
| 18 | Effect of pregnancy on clinical status and ventricular function in women with heart disease显示文摘 | Uebing A Arvanitis P Li W | 2010 | Int J Cardiot2010，139，1： | 1 |
| 19 | Pharmacokinetics, tolerability, and clinical effectiveness of quetiapine fumarate: an open label trial in adolescents with psychotic disorders 显示文摘 | Mcconville BJ Arvanitis LA Thyrum PT | 2000 | J Clin Psychiatry2000，61，4： | 1 |
| 20 | Building Models for Credit Spread 显示文摘 | Arvanitis A Gregory J and Laurent J P | 1999 | The Journal of Derivatives1999，，6： | 1 |
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