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| 1 | Acute upper gastrointestinal bleeding in octοgenarians:Clinical outcome and factors related to mortality显示文摘AIM: To evaluate the aetiology, clinical outcome and factors related to mortality of acute upper gastrointestinal bleeding (AUGIB) in octogenarians. METHODS: We reviewed the records of all patients over 65 years old who were hospitalised with AUGIB in two hospitals from January 2006 to December of 2006. Patients were divided into two groups: Group A (65-80 years old) and Group B (> 80 years old). RESULTS: Four hundred and sixteen patients over 65 years of age were hospitalized because of AUGIB. Group A included 269 patients and Group B 147 patients. Co-morbidity was more common in octogenarians (P = 0.04). The main cause of bleeding was peptic ulcer in both groups. Rebleeding and emergency surgery were uncommon in octogenarians and not different from those in younger patients. In-hospital complications were more common in octogenarians (P = 0.05) and more patients died in the group of octogenarians compared to the younger age group (P = 0.02). Inability to perform endoscopic examination (P = 0.002), presence of high risk for rebleeding stigmata (P = 0.004), urea on admission (P = 0.036), rebleeding (P = 0.004) and presenceof severe co-morbidity (P < 0.0001) were related to mortality. In multivariate analysis, only the presence of severe co-morbidity was independently related to mortality (P = 0.032). CONCLUSION: While rebleeding and emergency surgery rates are relatively low in octogenarians with AUGIB, the presence of severe co-morbidity is the main factor of adverse outcome. | George J Theocharis Vassiliki Arvaniti Stelios F Assimakopoulos Konstantinos C Thomopoulos Vassilis Xourgias Irini Mylonakou Vassiliki N Nikolopoulou | 2008 | World Journal of Gastroenterology2008,14,25: | 15 |
| 2 | Acute upper gastrointestinal bleeding in operated stomach: Outcome of 105 cases显示文摘AIM: To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past.METHODS: The causes and clinical outcome were compared between 105 patients with AUGB and a history of gastric surgery, and 608 patients with AUGB but without a history of gastric surgery.RESULTS: Patients who underwent gastric surgery in the past were older (mean age: 68.1±11.7 years vs 62.8±17.8 years, P= 0.001), and the most common cause of bleeding was marginal ulcer in 63 patients (60%). No identifiable source of bleeding could be found in 22 patients (20.9%) compared to 42/608 (6.9%) in patients without a history of gastric surgery (P = 0.003). Endoscopic hemostasis was permanently successful in 26 out of 35 patients (74.3%) with peptic ulcers and active bleeding or non-bleeding visible vessel. Nine patients (8.6%) were operated due to continuing or recurrent bleeding,compared to 23/608 (3.8%) in the group of patients without gastric surgery in the past (P= 0.028). Especially in peptic ulcer bleeding patients, emergency surgery was more common in the group of patients with gastric surgery in the past [9/73 (12.3%) vs 19/360 (5.3%), P = 0.025].Moreover surgically treated patients in the past required more blood transfusion (3.3±4.0 vs 1.5±1.7, P = 0.0001) and longer hospitalization time (8.6±4.0 vs 6.9±4.9 d,P = 0.001) than patients without a history of gastric surgery. Mortality was not different between the two groups [4/105 (3.8%) vs 19/608 (3.1%)].CONCLUSION: Upper gastrointestinal bleeding seems to be more severe in surgically treated patients than in non-operated patients. | Vassiliki N Nikolopoulou Konstantinos C Thomopoulos George I Theocharis Vassiliki A Arvaniti Constantine E Vagianos | 2005 | World Journal of Gastroenterology2005,11,29: | 9 |
| 3 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer显示文摘 | Schachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004,431,5: | 1 |
| 4 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer显示文摘 | SHACHAF C M KOPELMAN A M ARVANITIS C | 2004 | Nature2004,431,7012: | 1 |
| 5 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular carcinoma显示文摘 | Shachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004,431,: | 1 |
| 6 | Sustained loss of a neoplastic phenotype by brief inactivation of MYC显示文摘 | Arvanitis C Chu K | 2002 | Science2002,297,5578: | 1 |
| 7 | Presence of mec genes and overproduction of beta-lactamase in the expression of low-level methicillin resistance among staphylococci显示文摘 | Petinaki E Arvaniti A Bartzavali C | 2002 | Chemotherapy2002,48,4: | 1 |
| 8 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular显示文摘 | Shachaf C M Kopelman A M Arvanitis C | 2004 | Nature2004,431,: | 1 |
| 9 | Sustained loss of a neoplastic phenotype by brief inactivation of Myc显示文摘 | Jain M Arvanitis C Chu K | 2002 | Science2002,297,5578: | 1 |
| 10 | Sustainability analysis and benchmarking of olive mill wastewater treatment methods 显示文摘 | Zagklis D P Arvaniti E C Papadakis V G | 2013 | Journal of Chemical Technology and Biotechnology2013,88,: | 1 |
| 11 | Expression of heregulin in human coronary atherosclerotic lesions 显示文摘 | Panutsopulos D Arvanitis DL Tsatsanis C | 2005 | J Vase Res2005,42,6: | 1 |
| 12 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer显示文摘 | Shachaf C M Kopelman A M Arvanitis C | 2004 | Nature2004,431,: | 1 |
| 13 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer 显示文摘 | Shachaf C M Kopelman A M Arvanitis C | 2004 | Nature2004,431,7012: | 1 |
| 14 | Statistical properties of core network Internet traffic显示文摘 | C C Constantinou T N Arvanitis | 2002 | Electronics Letters2002,38,7: | 1 |
| 15 | Cognitive impairment is relat- ed to increased arterial stiffness and micrevascular damage in patients with never-treated essential hypertension显示文摘 | Triantafyllidi H Arvaniti C Lekakis J | 2009 | Am J Hypertens2009,22,5: | 1 |
| 16 | MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular Cancer显示文摘 | Shachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004,431,7012: | 1 |
| 17 | MYC inactivation uncovers pluripotent differentiation and tumor dormancy in hepatocelluar cancer显示文摘 | Shachaf CM Kopelman AM Arvanitis C | 2004 | Nature2004,431,7012: | 1 |
| 18 | Presence of mec genes and overproduction of beta-lactamase in the expression of lowlevel methicillin resistance among Staphylococci显示文摘 | PETINAKI E ARVANITI A BARTZAVALI C | | 0,,04: | 1 |
| 19 | Sustained loss of a neoplastic phenotype by brief inactivation of MYC显示文摘 | Jain M Arvanitis C Chu K | | 0,,5578: | 1 |
| 20 | Sustained loss of a neoplastic phenotype by brief inactivation of MYC 显示文摘 | Jain M Arvanitis C Chu K | 2002 | Science2002,297,5578: | 1 |