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| 1 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021，20，2： | 5 |
| 2 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 3 | Differentiation of malignant and benign proximal bile duct strictures: The diagnostic dilemma显示文摘AIM: To identify the criteria for the differentiation of hilar cholangiocarcinoma (HCCA) from benign strictures. METHODS: A total of 68 patients underwent resection of lesions suspicious for HCCA between 1998 and 2006. The results of laboratory investigations, imaging studies and brush cytology were collected. These fi ndings were analyzed to obtain the fi nal diagnosis. RESULTS: Histological examination of the resected specimens confirmed HCCA in 58 patients (85%, group Ⅰ) whereas 10 patients (15%, groupⅡ) were diagnosed to have benign strictures. The most common presenting symptom was obstructive jaundice in 77% patients (79% group Ⅰvs 60% group Ⅱ P = 0.23). Laboratory findings showed greater elevation of transaminase levels in group Ⅰcompared to group Ⅱ The various imaging modalities showed vascular involvement exclusively in the malignant group (36%,P < 0.05). Brush cytology was positive for malignant cells in only 50% patients in group Ⅰ whereas none in group Ⅱ showed malignant cells. CONCLUSION: Despite improvements in imaging techniques, 10 patients (15%) with a presumptive diagnosis of HCCA were ultimately found to have benign strictures. Except for vascular involvement which was associated significantly with malignancy, there were no conclusive features of malignancy on regular imaging modalities. This uncertainty should be taken into account when patients with a suspicious lesion at the liver hilum are considered for resection. | Jaap Jacob Kloek Otto Marinus van Delden Deha Erdogan Fibo Jan ten Kate Erik Anthoni Rauws Olivier Robert Busch Dirk Joan Gouma Thomas Mathijs van Gulik | 2008 | World Journal of Gastroenterology2008，14，32： | 2 |
| 4 | Negligible risk of inducing resistance in Mycobacterium tuberculosis with single-dose rifampicin as post-exposure prophylaxis for leprosy显示文摘Post-exposure prophylaxis(PEP)for leprosy is administered as one single dose of rifampicin(SDR)to the contacts of newly diagnosed leprosy patients.SDR reduces the risk of developing leprosy among contacts by around 60%in the first 2–3 years after receiving SDR.In countries where SDR is currently being implemented under routine programme conditions in defined areas,questions were raised by health authorities and professional bodies about the possible risk of inducing rifampicin resistance among the M.tuberculosis strains circulating in these areas.This issue has not been addressed in scientific literature to date.To produce an authoritative consensus statement about the risk that SDR would induce rifampicin-resistant tuberculosis,a meeting was convened with tuberculosis(TB)and leprosy experts.The experts carefully reviewed and discussed the available evidence regarding the mechanisms and risk factors for the development of(multi)drug-resistance in M.tuberculosis with a view to the special situation of the use of SDR as PEP for leprosy.They concluded that SDR given to contacts of leprosy patients,in the absence of symptoms of active TB,poses a negligible risk of generating resistance in M.tuberculosis in individuals and at the population level.Thus,the benefits of SDR prophylaxis in reducing the risk of developing leprosy in contacts of new leprosy patients far outweigh the risks of generating drug resistance in M.tuberculosis. | Liesbeth Mieras Richard Anthony Wim van Brakel Martin W.Bratschi Jacques van den Broek Emmanuelle Cambau Arielle Cavaliero Christa Kasang Geethal Perera Lee Reichman Jan Hendrik Richardus Paul Saunderson Peter Steinmann Wing Wai Yew | 2016 | Infectious Diseases of Poverty2016，5，1： | 2 |
| 5 | High Prevalence of Anti‐Apolipoprotein/A‐1 Autoantibodies in Maintenance Hemodialysis and Association With Dialysis Vintage显示文摘 | Menno Pruijm Jan Schmidtko Anthony Aho Sabrina Pagano Pascale Roux‐Lombard Daniel Teta Michel Burnier Nicolas Vuilleumier | 2012 | Therapeutic Apheresis and Dialysis2012，，6： | 1 |
| 6 | The Leiden ranking 2011/2012: Data collection, indicators, and interpretation显示文摘 | Ludo Waltman Clara Calero‐Medina Joost Kosten Ed C.M. Noyons Robert J.W. Tijssen Nees Jan Eck Thed N. Leeuwen Anthony F.J. Raan Martijn S. Visser Paul Wouters | 2012 | J Am Soc Inf Sci Tec2012，，12： | 1 |
| 7 | Functional biology of the α2δ1 subunits of voltage - gated calcium channels 显示文摘 | Anthony Daviesa Jan Hendricha Alexandra Tran Van Minha | 2007 | Trends in Pharmacological Sciences2007，28，5： | 1 |
| 8 | Towards a new crown indicator: Some theoretical considerations显示文摘 | Ludo Waltman Nees Jan van Eck Thed N. van Leeuwen Martijn S. Visser Anthony F.J. van Raan | 2010 | Journal of Informetrics2010，，1： | 1 |
| 9 | Practice Parameters for Colon Cancer显示文摘 | Daniel Otchy Neil H. Hyman Clifford Simmang Thomas Anthony Donald W. Buie Peter Cataldo James Church Jeffrey Cohen Frederick Dentsman Neal C. Ellis John W. Kilkenny Clifford Ko Richard Moore Charles Orsay Ronald Place Janice Rafferty Jan Rakinic Paul Savo | 2004 | Diseases of the Colon & Rectum2004，，： | 1 |
| 10 | Design Op- timisation for the Vertical Suspension of a Crop Sprayer Boom显示文摘 | Anthonis jan Audenaert Jorgen Ramon Herman | 2005 | Biosystems Engineering2005，90，2： | 1 |
| 11 | Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression显示文摘 | Daniele Torella Marcello Rota Daria Nurzynska Ezio Musso Alyssa Monsen Isao Shiraishi Elias Zias Kenneth Walsh Anthony Rosenzweig Mark A. Sussman Konrad Urbanek Bernardo Nadal-Ginard Jan Kajstura Piero Anversa Annarosa Leri | 2004 | Circulation Research: Journal of the American Heart Association2004，，4： | 1 |
| 12 | Meiosis activating sterols derived from diosgenin显示文摘 | ANTHONY Murray CHRISTIAN Grondahl JAN L Ottesn | 2002 | Bioorganic & Medicinal Chemistry Letters2002，12，： | 1 |
| 13 | Im- provement of vibrational comfort on agricultural vehicles by passive and semi-active cabin suspensions 显示文摘 | Deprez Koen Moshou Dimitrios Anthonis Jan | 2005 | Computers and Electronics in Agriculture2005，49，： | 1 |
| 14 | Functional biology of the α 2 δ subunits of voltage-gated calcium channels显示文摘 | Anthony Davies Jan Hendrich Alexandra Tran Van Minh Jack Wratten Leon Douglas Annette C. Dolphin | 2007 | Trends in Pharmacological Sciences2007，，5： | 1 |
| 15 | Improvement of vibration comfort on agriculture vehicles by passive and semi-active cabin suspension 显示文摘 | DeprezKoen Moshou Dimitrios Anthonis Jan | 2005 | Computers and Electronics in Agriculture2005，49，： | 1 |
| 16 | Improving rural education in Poland显示文摘 | Anthony Levitas Stanis? awa Golinowska Jan Herczyfiski | 2001 | The center for social and economy research2001，，3： | 1 |
| 17 | When and how to develop Domain Specific Languages 显示文摘 | M Marjan H Jan M S Anthony | 2005 | ACM Computing Surveys2005，37，： | 1 |
| 18 | Tibetan sacred sites conserve old growth trees and cover in tile eastern Himalayas显示文摘 | JAN S ANTHONY A DANICA A | 2007 | Biodiversity and Conservation2007，16，： | 1 |
| 19 | Bulky diphosphite-modified rhodium catalysts: hydrofomaylation and characterization显示文摘 | Almemiek V R Paul C J K Piet W N M L Kees G Jan F Nora V Anthony L S | | 0，，： | 1 |
| 20 | Improvement of vibrational comfort on agricultural vehicles by passive and semi-active cabin suspensions 显示文摘 | Deprez Koen Moshou Dimitrios Anthonis Jan | 2005 | Computers and Electronics in Agriculture2005，49，3： | 1 |
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