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| 1 | Brugada拟表型:一个新的临床实体显示文摘Brugada拟表型(Brugada phenocopy,BrP)是临床实体,它与真正的Brugada综合征(Brugada syndrome,BrS)具有相同的心电图波形,但前者是由各种临床状况诱发的。在某种相关的潜隐状况下,BrP的特征表现为心前区导联V1~V3呈1型或2型Brugada心电图波形。随着潜隐状况的纠正,这些心电图波形恢复正常。本研究中,我们回顾了BrP的分类、与BrS鉴别的方法及有关BrP病因的最新研究结果。此外,我们提供了BrP国际在线注册的更新数据,并讨论了BrP未来的研究方向。 | Byron H Gottschalk Daniel D Anselm Adrian Baranchuk 蒋祖勋 | 2015 | 江苏实用心电学杂志2015，0，4： | 5 |
| 2 | 论经济发展中市场与政府的关系显示文摘发展中国家在经济发展中面临着市场经济不发达的问题。市场经济不发达是经济落后的重要表现,也是发展中国家在发展经济过程中遇到的重大障碍。不发达的市场经济体制限制了市场机制作用的发挥,因此,经济的迅速发展离不开政府的推动。本文论述经济发展中市场机制的作用和政府的经济职能,分析经济发展中的市场失效和政府失效问题,探讨市场与政府相结合的方式。 | 周军 ANDRIAMAHERY Anselme 万倩倩 | 2019 | 当代经济2019，36，4： | 4 |
| 3 | 2013 ESC guidelines on the management of stable coronary artery disease显示文摘 | Gilles Montalescot Udo Sechtem Stephan Achenbach Felicita Andreotti Chris Arden Andrzej Budaj Raffaele Bugiardini Filippo Crea Thomas Cuisset Carlo Di Mario J. Rafael Ferreira Bernard J. Gersh Anselm K. Gitt Jean-Sebastien Hulot Nikolaus Marx Lionel H. Op | 2013 | European Heart Journal2013，，38： | 4 |
| 4 | Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales显示文摘 | C.P Wilkinson Frederick L Ferris Ronald E Klein Paul P Lee Carl David Agardh Matthew Davis Diana Dills Anselm Kampik R Pararajasegaram Juan T Verdaguer | 2003 | Ophthalmology2003，，9： | 4 |
| 5 | Chronic ulcerative gastroduodenitis as a first gastrointestinal manifestation of Hermansky-Pudlak syndrome in a 10-year-old child显示文摘A 10-year-old Chinese boy who had a history of congenital thrombocytopathy presented with severe iron deficiency anemia secondary to chronic gastric inflammation and duodenal ulcerations. Subtle oculocutaneous albinism led to the finding of diminished dense bodies in the platelets under electron microscopy, hence the diagnosis of Hermansky-Pudlak syndrome (HPS). Biopsies from the stomach and duodenum revealed a lymphocytic infiltration in the submucosa, but H pylori infection was absent. The gastroduodenitis responded to the treatment with omeprazole while iron deficiency anemia was corrected by oral iron therapy. HPS is a rare cause of congenital bleeding disorder with multisystemic manifestations. Upper gastrointestinal involvement is rare and should be distinguished from a mere manifestation of the bleeding diathesis. | Anselm Chi-Wai Lee Kin-Hung Poon Wing-Hong Lo Lap-Gate Wong | 2008 | World Journal of Gastroenterology2008，14，18： | 4 |
| 6 | Role of wide-field autofluorescence imaging and scanning laser ophthalmoscopy in differentiation of choroidal pigmented lesions显示文摘·AIM:Toevaluatethe diagnostic properties of wide-field fundus autofluorescence(FAF) scanning laser ophthalmoscope(SLO) imaging for differentiating choroidal pigmented lesions.·METHODS: A consecutive series of 139 patients were included, 101 had established choroidal melanoma with13 untreated lesions and 98 treated with radiotherapy.Thirty-eight had choroidal nevi. All patients underwent a full ophthalmological examination, undilated wide-field imaging, FAF and standardized US examination. FAF images and imaging characteristics from SLO were correlated with the structural findings in the two patient groups.·RESULTS: Mean FAF intensity of melanomas was significantly lower than the FAF of choroidal nevi. Only 1out of 38 included eyes with nevi touched the optic disc compared to 31 out of 101 eyes with melanomas. In 18 out of 101 melanomas subretinal fluid was seen at the pigmented lesion compared to none seen in eyes with confirmed choroidal nevi. In 'green laser separation', a trend towards more mixed FAF appearance of melanomas compared to nevi was observed. The mean maximal and minimal transverse and longitudinal diameters of melanomas were significantly higher than those of nevi.·CONCLUSION: Wide-field SLO and FAF imaging may be an appropriate non-invasive diagnostic screening tool to differentiate benign from malign pigmented choroidal lesions. | Lukas Reznicek Carmen Stumpf Florian Seidensticker Anselm Kampik Aljoscha S Neubauer Marcus Kernt | 2014 | International Journal of Ophthalmology(English edition)2014，7，4： | 3 |
| 7 | Effect of serum γ-glutamyltranferase and albumin levels on the response to cardiac resynchronization therapy in the elderly显示文摘Background Several liver function tests have been identified as predictors of hospitalization for heart failure(HF) and death in patients with chronic HF. The relationship between serum γ-glutamyltranferase(GGT) and albumin(SA) levels with the response to cardiac resynchronization therapy(CRT) has not been reliably determined. The aim of the study was to evaluate the impact of liver function tests on the results of CRT in the elderly. Methods Baseline GGT and SA were assessed before CRT device implantation in the elderly(> 70-year-old) patients. The endpoints were:(1) CRT response defined as > 5% left ventricular ejection fraction improvement and no hospitalization for HF or cardiovascular death;(2) hospitalizations;and(3) mortality. Results Eighty of 138(58%) included patients were responders at nine months. Compared to responders, the SA levels were not significantly different(35.1 ± 5.4 vs. 33.6 ± 5.5 g/L, P = 0.103);but the GGT levels, higher(81.6 ± 69.3 vs. 54.7 ± 49.6 U/L, P = 0.013) in non-responders to CRT. GGT level was independently associated with non-response to CRT(P < 0.001, OR = 0.17;95% CI: 0.08–0.38, P < 0.001). GGT cut-off value ≥ 55 U/L was highly predictive of non-response [AUC = 0.65, 64% Sensitivity, 69% Specificity(95% CI: 0.56–0.74)]. GGT ≥ 55 U/L was also associated with higher risk of hospitalization for atrial fibrillation(AF)(95% vs. 83%, P = 0.024). Both SA and GGT had no impact on overall(P = 0.220, P = 0.723) mortality. Conclusions Higher level of GGT is an independent predictor of non-response to CRT in patients over age 70 years and is associated with higher risk of hospitalization for AF. Baseline serum levels of albumin and GGT and have no impact on mortality in elderly patients undergoing CRT. | Maciej Kubala Alexis Hermida Otilia Buiciuc Pierre-Marc Lallemand Geneviève Bertaina Frédéric Anselme Didier Klug Momar Diouf Jean-Sylvain Hermida | 2020 | Journal of Geriatric Cardiology2020，17，6： | 3 |
| 8 | Brugada phenocopy: A new electrocardiogram phenomenon显示文摘Brugada phenocopies(BrP) are clinical entities that are etiologically distinct from true congenital Brugada syndrome. BrP are characterized by type 1 or type 2 Brugada electrocardiogram(ECG) patterns in precordial leads V1-V3. However, BrP are elicited by various un-derlying clinical conditions such as myocardial ischemia, pulmonary embolism, electrolyte abnormalities, or poor ECG filters. Upon resolution of the inciting underlying pathological condition, the BrP ECG subsequently nor-malizes. To date, reports have documented BrP in the context of singular clinical events. More recently, recur-rent BrP has been demonstrated in the context of re-current hypokalemia. This demonstrates clinical repro-ducibility, thereby advancing the concept of this new ECG phenomenon. The key to further understanding the pathophysiological mechanisms behind BrP requires experimental model validation in which these phenom-ena are reproduced under strictly controlled environ-mental conditions. The development of these validation models will help us determine whether BrP are tran-sient alterations of sodium channels that are not repro-ducible with a sodium channel provocative test or al-ternatively, a malfunction of other ion channels. In this editorial, we discuss the conceptual emergence of BrP as a new ECG phenomenon, review the progress made to date and identify opportunities for further investiga-tion. In addition, we also encourage investigators that are currently reporting on these cases to use the term BrP in order to facilitate literature searches and to help establish this emerging concept. | Daniel D Anselm Jennifer M Evans Adrian Baranchuk | 2014 | World Journal of Cardiology2014，6，3： | 2 |
| 9 | Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales显示文摘 | C.P Wilkinson Frederick L Ferris Ronald E Klein Paul P Lee Carl David Agardh Matthew Davis Diana Dills Anselm Kampik R Pararajasegaram Juan T Verdaguer | 2003 | Ophthalmology2003，，9： | 2 |
| 10 | Correlation of leaking microaneurysms with retinal thickening in diabetic retinopathy显示文摘AIM: To investigate the contribution of fluorescein angiographic leaking microaneurysms (leak-MA) versus non-leaking microaneurysms (non-leak-MA) to retinal thickening in diabetic retinopathy.METHODS: A consecutive series of 38 eyes from 24 patients with diabetic retinopathy was included.Leak-MA and non-leak-MA in each eye were selected in pairs at corresponding topographic location.Leaking was defined by late phase fluorescein angiograms compared to early phase.Retinal thickness was measured with Heidelberg Spectralis OCT topographically aligned on early phase angiograms at the MA site and within a 1 mm circle.RESULTS: In all eyes,significant retinal thickening at the site of leaking compared to non-leaking microaneurysms was observed (356±69μm vs 318±56μm,P <0.001),showing a mean increase in thickness in the areas of leak-MA vs non-leak-MA of 38±39μm (95% confidence interval 2551μm,P<0.001).All 1mm area measurements also showed significant (P<0.001) thickening of the leak-MA with average thickness of leak-MA vs non-leak-MA as 351±67μmvs 319±59μm;minimum thickness 311±62μm vs 284±60μm;maximum thickness 389±78μm vs 352±66μm;and retina volume 26.4±6.0mmvs 23.6±3.7mm3,respectively.CONCLUSION: Leaking of microaneurysms on fluorescein angiography appears to cause focal thickening of retina,which can be measured with high-resolution OCT.Therefore,targeting leaking microaneursyms in diabetic retinopathy has the potential to reduce retinal thickening. | Lukas Reznicek Marcus Kernt Christos Haritoglou Michael Ulbig Anselm Kampik Aljoscha S Neubauer | 2011 | International Journal of Ophthalmology(English edition)2011，4，3： | 2 |
| 11 | Intra-aortic balloon pump in patients with acute myocardial infarction complicated by cardiogenic shock: results of the ALKK-PCI registry显示文摘 | Uwe Zeymer Mathias Hochadel Karl-Eugen Hauptmann Klaus Wiegand Burghard Schuhmacher Johannes Brachmann Anselm Gitt Ralf Zahn | 2013 | Clinical Research in Cardiology2013，，： | 2 |
| 12 | Qualitative and quantitative study of human osteoblast adhesion on materials with various surface roughness显示文摘 | Anselme K Bigerelle M Noel B | 2000 | J Biomed Mater Res2000，49，： | 1 |
| 13 | A Dynamic Model for Predicting Fouling Effects During the Uhrafihration of a Groundwater 显示文摘 | Wetterau G E Clark M M Anselme C | 1996 | Journal of Membrane Science1996，109，： | 1 |
| 14 | Osteoblast adhesion on biomaterials显示文摘 | Anselme K | | Biomaterials0，21，7： | 1 |
| 15 | Topography effects of pure titanium substrates on human osteoblast long - term adhesion 显示文摘 | Anselme K Bigerelle M | 2005 | Acta Biomater2005，1，2： | 1 |
| 16 | New insights on contact angle/roughness dependence on high surface energy materials 显示文摘 | Giljean S Bigerelle M Anselme K | 2011 | Applied Surface Science2011，257，22： | 1 |
| 17 | Nine-Year Incidence and Risk Factors for Pterygium in the Barbados Eye Studies显示文摘 | Barbara Nemesure Suh-Yuh Wu Anselm Hennis M. Cristina Leske | 2008 | Ophthalmology2008，，12： | 1 |
| 18 | Catheter ablation of typical atrial flutter: A randomized comparison of 2 methods for determining complete bidirectional isthmus block 显示文摘 | Savoure A Cribier A | 2001 | Circulation2001，103，10： | 1 |
| 19 | Relative influence of the topography and chemistry of TiAl6V4 surfaces on osteoblastic cell behaviour 显示文摘 | Anselme K Linez P Bigerelle M Le Maguer D Le Maguer A Hardouin P Hildebrand H F Iost A Leroy J M | 2000 | Biomaterials2000，21，： | 1 |
| 20 | Impact of ultrafiltration operating condition on membrane irreversible fouling显示文摘 | G F Crozes J Gjacagelo C Anselme | 1997 | Journal of Membrane Science1997，124，1： | 1 |
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