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| 1 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018,28,9: | 18 |
| 2 | Ginseng pharmacology显示文摘 | Anoja S Attele Ji An Wu Chun-Su Yuan | 1999 | Biochemical Pharmacology1999,,11: | 2 |
| 3 | Anti-HIV activity of medicinal herbs : usage and potential development 显示文摘 | Ji An Wu Anoja S Attele Liu Zhang | 2001 | Am J Chin Med2001,29,1: | 1 |
| 4 | Antidiabetic Effects of Panax ginseng Berry Extractand the Identitication of an Effective Component显示文摘 | Anoja S Attele Yun-Ping Zhou | 2002 | DIABETES2002,51,6: | 1 |
| 5 | Ginseng pharmacology, multiple con- stituents and multiple actions 显示文摘 | Anoja SA Wu JA Yuan CS | 1999 | Biochem Pharmacol1999,58,5: | 1 |
| 6 | Atypical manifestations of chikungunya infection显示文摘 | Senaka Rajapakse Chathuraka Rodrigo Anoja Rajapakse | 2009 | Transactions of the Royal Society of Tropical Medicine and Hygiene2009,,2: | 1 |
| 7 | Isolation and purification of an anticoagulant from fermented red seaweed Lomentaria catenata 显示文摘 | Wickramaarachchilage Anoja Pushpamali Chamilani Nikapitiya Mahanama De Zoysa | 2008 | Carbohydrate Polymers2008,73,: | 1 |
| 8 | Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component显示文摘 | Anoja A Zhou YP Xian JT | 2002 | Diabetes2002,51,6: | 1 |
| 9 | Antidiabetic Effects of Panaxginseng Berry Extract and the Identification of an Effective Component显示文摘 | Anoja S Attele Yun-Ping Zhou | 2002 | Diabetes2002,51,6: | 1 |
| 10 | Ginseng pharmacology, multiple constituents and multiple actions显示文摘 | Anoja SA Wu JA Yuan CS | 1999 | Biochem Pharmacol1999,58,: | 1 |
| 11 | Two-day enema antibiotic therapy for parasite eradication and resolution of symptoms显示文摘BACKGROUND Blastocystis hominis(B.hominis)and Dientamoeba fragilis(D.fragilis)are two protozoan parasites of human bowel that are found throughout the world.There is still debate about the pathogenicity of these protozoans,despite them being commonly associated with gastrointestinal symptoms and can cause health issue in both children and adults.These parasites are usually transmitted through faecal-oral contact particularly under poor hygiene conditions or food/water contamination.Once a person is infected,the parasites live in the large intestine and are passed in the faeces.AIM To investigate the effect of triple antibiotic therapy using enema infusion in the treatment of B.hominis and D.fragilis infections.METHODS This retrospective longitudinal study was conducted in a single medical centre,which included fifty-four patients(≥18 years)who were positive for D.fragilis,B.hominis or both between 2017 and 2018.The treatment consisted of triple antibiotics that were infused over two consecutive days through rectal enema.Faecal samples were collected from participants pre-and post-treatment and were tested for parasites using microscopy and polymerase chain reaction.Patients’symptoms were recorded prior and after the treatment as well as patient demographic data.RESULTS Patients(n=54),were either positive for B.hominis(37%),D.fragilis(35%)or both(28%).All patients completed the two-day treatment and no serious adverse effect was reported.The most common side effect experienced by the patients during the treatment was urine discolouration which was cleared by six weeks of followup.Common symptoms reported prior to treatment were diarrhoea,abdominal pain,constipation and fatigue.Other symptoms included abdominal discomfort,dizziness and blood in the stool.Eighty-nine percent of patients completed a final stool test post-treatment.At six weeks post-treatment,79%of patients cleared the parasites from their faeces.Symptoms such as abdominal discomfort,dizziness and blood in the stool decreased significantly at both seven days and six weeks post-treatment(P<0.040).The enema retention time,bowel preparation,previous antibiotic treatment or previous gastrointestinal problems had no significant effect on parasite eradication.CONCLUSION Overall,eradication of parasites and improvement of clinical outcomes were observed in treated patients,showing the efficacy of this combination to eradicate the parasites and provide positive clinical outcome. | Niloufar Roshan Annabel Clancy Anoja W Gunaratne Antoinette LeBusque Denise Pilarinos Thomas J Borody | 2020 | World Journal of Gastroenterology2020,26,26: | 0 |
| 12 | South Asian medicinal plants and chronic kidney disease显示文摘Chronic kidney disease remains as one of the serious health issues in South Asia.The paucity of effective pharmacotherapy targeting the management of chronic kidney disease has led to a search for alternative pharmacologic therapies.The traditional knowledge of medicinal plants plays a key role in the discovery of novel nephroprotective agents.This review aims to present the use of such South Asian ethnomedicinal plants that have sufficient therapeutic potency for the management of kidney diseases.Medicinal plants are rich sources of bioactive compounds that have been reported to exert nephroprotective mechanisms,such as antioxidant,anti-inflammation,diuretic,and immunomodulation.Many South Asian medicinal plants have been detailed in traditional medicinal pharmacopoeias for the management of kidney-related diseases.Some have shown promising effects to address nephropathy in animal models and in vitro research.This information can be beneficial in the development of novel pharmaceutical agents targeting the management of kidney diseases and improvement of quality of life for chronic kidney disease patients by fulfilling the requirements for disease management unmet by modern allopathic medicine. | Sachinthi Sandaruwani Amarasiri Anoja Priyadarshani Attanayake Kamani Ayoma Perera Wijewardana Jayatilaka Lakmini Kumari Boralugoda Mudduwa | 2020 | Traditional Medicine Research2020,5,5: | 0 |