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357篇 您的检索式:作者名="Angelo R"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A recep- tom显示文摘MANIYKTA P K ANGELO O R MATHEUS M R 2004Nemvscience Letters2004,355,:1
3Neostigmine combined with bupivacaine, clonidine, and sufentanil for spinal labor analgesia显示文摘D'Angelo R Dean LS Meister GC 2001Anesth Analg2001,93,6:1
4Wet air oxidation of caustic liquors显示文摘De Angelo D J Wilhehni A R 1983Chemical Engineering Process1983,79,3:1
5P-glyeoprotein 170 expression and function as an adverse independent prognostic factor in childhood acute lymphoblastic leukemia显示文摘Casal F D angelo V Addeo R 2004Oncol Rep2004,12,:1
6Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease 显示文摘Tarawneh R D' Angelo G Macy E 2011Ann Neurol2011,70,2:1
7Deep dephosphorization treatments for steel显示文摘Borgianni C Angelo R D 1991Ctajib1991,3,:1
8Proposed refinement to the superpave high temperature specification parameter for performance graded binder 显示文摘Bouldin M G Dongre R D'Angelo J 2001Transportation Research Record2001,,1766:1
9Intrathecal neostig-mine and sufentanil for early labor analgesia显示文摘Nelson KE D'Angelo R Foss ML et a1 0,,91:1
10Creep and recovery显示文摘D Angelo J A R Dongre G Reinke 2007Public roads2007,,70:1
11New techniques for labor analgesia: PCEA and CSE显示文摘D'Angelo R 2003Clin Obste Gynecol2003,46,3:1
12Treatment of landfill leachate by reverse osmosis显示文摘Angelo C Rolando R Nicola V 1999Water Research1999,33,3:1
13Hydrodynamical modeling of charge carrier transport in semiconductors显示文摘Angelo M A Vittorio R 2000Overviews and Tutorials2000,35,:1
14Tollip is a mediator of protein sumoylation显示文摘Ciarrocchi A D Angelo R Cordiglieri C 2009PLoS One2009,4,2:1
15A comparison of remifentanil and morphine sulfate for acute postoperative analgesia after total intravenous anesthesia with remifentanil and propofol 显示文摘Yarmush J D'Angelo R Kirkhart B 1997Anesthesiology1997,87,2:1
16Preemptive analgesia for postoperative pain control:a review显示文摘Laura C Guglielmo C Angelo R D 2010Clin Drug invest-ing2010,30,2:1
17New techniques for labor analgesia:PCEA and CSE显示文摘D'Angelo R 2003Clin Obstet Gynecol2003,46,3:1
18Anticoagulant and aspirin prophylaxis for preventing thromboembolism after major gynecological surgery显示文摘Oates-Whitehead R M DAngelo A Mol B 2004Br J Perioper Nurs2004,14,7:1
19P-glycoprotein 170 expression and function as an adverse independent prognostic factor in childhood acute lymphoblastic leukemia 显示文摘Casale F D'Angelo V Addeo R 2004Oncol Rep2004,12,6:1
20Lipid oxi-dation in foods显示文摘Vercellotti J R Angelo A J S Spanier A M 1996Critical Reviews in Food Scienceand Nutrition1996,36,3:1
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