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| 1 | Internet-based collaborative pseudo-dynamic testing of multi-span bridge structure显示文摘In this paper, the first Internet-based collaborative pseudo-dynamic testing of a multi-span bridge system in China's Mainland is presented in detail, which has been carried out by the collaboration of Hunan University (HNU), Harbin Institute of Technology (HIT) and Tsinghua University (TU) in China's Mainland, and the University of Southern California (USC) in the USA. The prototype system of Russion River Bridge at Southern California in America is illustrated. Different testing specimens, testing equipments and substructure boundary conditions at HNU and HIT laboratories are described. A network protocol platform for collaborative pseudo-dynamic testing, called NetSLab, and some function modules developed on the use of its standardized interface are introduced. Aiming at the MTS system widely used in structural testing, two approaches are presented to implement the communication interface between NetSLab and testing equipment, respectively, studied by HNU and HIT. The integrated networked testing system and collaborative testing procedures are presented. The testing results manifest that the networked collaborative testing system with powerful capability provides a testing platform with good coordination for complex models or actual structures, and achieves remote sharing of testing equipments. | Dapeng Wang a, Shizhu Tiana, Xinjiang Caia, Yunlei Fan b, Yan Xiaob,c a School of Civil Engineering, Harbin Institute of Technology, Harbin 150090, China b School of Civil Engineering, Hunan University, Changsha 410082, China c Department of Civil Engineering, University of Southern California, Los Angeles, CA 90089, USA | 2009 | Progress in Natural Science:Materials International2009，19，5： | 4 |
| 2 | Epigenetic basis of Alzheimer disease显示文摘Alzheimer disease(AD)is the primary form of dementia that occurs spontaneously in older adults.Interestingly,the epigenetic profile of the cells forming the central nervous system changes during aging and may contribute to the progression of some neurodegenerative diseases such as AD.In this review,we present general insights into relevant epigenetic mechanisms and their relationship with aging and AD.The data suggest that some epigenetic changes during aging could be utilized as biomarkers and target molecules for the prevention and control of AD. | Angeles C Tecalco-Cruz JosuéO Ramírez-Jarquín María E Alvarez-Sánchez Jesus Zepeda-Cervantes | 2020 | World Journal of Biological Chemistry2020，11，2： | 4 |
| 3 | Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study显示文摘 | William C Huang Andrew S Levey Angel M Serio Mark Snyder Andrew J Vickers Ganesh V Raj Peter T Scardino Paul Russo | 2006 | Lancet Oncology2006，，9： | 4 |
| 4 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 5 | Polyubiquitination inhibition of estrogen receptor alpha and its implications in breast cancer显示文摘Estrogen receptor alpha(ERα) is detected in more than 70% of the cases of breast cancer. Nuclear activity of ERα, a transcriptional regulator, is linked to the development of mammary tumors, whereas the extranuclear activity of ERα is related to endocrine therapy resistance. ERα polyubiquitination is induced by the estradiol hormone, and also by selective estrogen receptor degraders, resulting in ERα degradation via the ubiquitin proteasome system. Moreover, polyubiquitination is related to the ERα transcription cycle, and some E3-ubiquitin ligases also function as coactivators for ERα. Several studies have demonstrated that ERα polyubiquitination is inhibited by multiple mechanisms that include posttranslational modifica-tions, intera-ctions with coregula-tors, a-nd forma-tion of specific protein complexes with ERα. These events are responsible for an increase in ERα protein levels and deregulation of its signaling in breast cancers. Thus, ERα polyubiquitination inhibition may be a key factor in the progression of breast cancer and resistance to endocrine therapy. | Angeles C Tecalco-Cruz Josué O Ramírez-Jarquín | 2018 | World Journal of Clinical Oncology2018，9，4： | 2 |
| 6 | Gastric cancer in young people under 30 years of age: worse prognosis, or delay in diagnosis?显示文摘 | Horacio N López-Basave Diaz Romero C Alejandro Padilla Rosciano Melchor Ruan J Silvio A. ?amendys-Silva Vela Sarmiento I Ruiz Molina JM Calderillo Ruiz G Flavia Morales-Vásquez Abelardo Meneses Garcia Angel Herrera-Gomez | 2013 | Cancer Management and Research (default)2013，，： | 2 |
| 7 | Realization theorems for categories of graded module over semigroup- graded ring显示文摘 | Abrams G Menimi C Angel Del Rio | 1994 | CommAlgebra1994，22，13： | 1 |
| 8 | Singularity Analysis of Closed Loop Kinematic Chains显示文摘 | Gosselin C Angeles J | 1990 | IEEE Transactions on Robotics and Automation1990，6，3： | 1 |
| 9 | Blood copper levels in mexiaean users of the TCu380A IUD 显示文摘 | Dolores D Angeles C Maricela A | 2005 | Contraception2005，72，1： | 1 |
| 10 | Singularity Analysis of Closed-loop Kinematic Chains显示文摘 | Gosselin C M Angeles J | 1990 | IEEE Transactions on Robotics and Automation1990，6，3： | 1 |
| 11 | Pprotonic semiconducting glasses from aqueous solution显示文摘 | Angell C A Bressel RD | 1972 | J Non-Crystalline Solids1972，7，： | 1 |
| 12 | A review of experi mental procedures for heavy oil hydroeracking with dispersed catalyst显示文摘 | Angeles M J Leyva C Ancheyta J | 2014 | Catalysis Today2014，220，： | 1 |
| 13 | Radiofrequency volumetric tissue reduction for treatment of turbinate hypertrophy in children显示文摘 | O'CONNOR-REINA C GARCIA-IRIATE M T ANGEL D G | 2007 | Int J Pediatr Othrhinolaryn- go12007，71，4： | 1 |
| 14 | Effect of Dietary Calcium and Vitamin D3 on Calcium and Phosphorus Retention in White Pekin Ducklings 显示文摘 | Rush J K Angel C R Banks K M | 2005 | Poult Sci2005，84，： | 1 |
| 15 | Formation of glasses from liquids and biopolymers显示文摘 | Angell C A | 1995 | Science1995，267，： | 1 |
| 16 | B6zier curve and surface fitting of 3D point clouds through genetic algorithms显示文摘 | AKEMI G ANDRes I ANGEL C | 2007 | Lecture Notes in Computer Science2007，4706，： | 1 |
| 17 | McCullough Angioleiomyoma on the Hard palate 显示文摘 | AI - amad SH Angel C O 'Grady JF | 2006 | Oral Oncol2006，42，： | 1 |
| 18 | Singularity analysis of closed-loop kinematic chains 显示文摘 | Gosselin C Angeles J | 1990 | IEEE Transactions on Robotics and Automation1990，6，3： | 1 |
| 19 | Singularity analysis of closed - loop kinematic chains显示文摘 | Gosselin C Angeles J | 1990 | IEEE Transactions on Ro- botics and Automation1990，6，3： | 1 |
| 20 | A survey of DNA polymorphism within the genus Capsicum and the fingerprinting of pepper cultivars显示文摘 | Prince J P Lackney V K Angeles C | 1995 | Genome1995，38，： | 1 |
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