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| 1 | 亚太地区胃食管反流病的处理共识:更新版显示文摘背景与目的:自从2004年亚太地区胃食管反流病(GERD)共识发表以来,更多关于GERD流行病学和处理的文献资料相继出现。有必要对这些资料进行循证综述,对共识作出更新。方法:由多学科专家组应用德尔菲(Delphi)法制定共识条文,提呈相关资料,并对证据质量、推荐力度和共识水平进行分级。结果:亚洲GERD发生率日益增加。其危险因素包括老年、男性、种族、家族史、社会经济地位高、体重指数增加和吸烟。对于有典型症状而无报警症状的患者,对质子泵抑制剂(PPI)试验有症状应答具有诊断意义。如PPI试验失败,停止治疗后pH监测结果阴性可排除GERD。窄带成像、胶囊内镜检查和无线pH监测的作用尚未明确。亚洲诊断策略的制定须考虑到并存的胃癌和消化性溃疡。减轻体质量和抬高床头可改善反流症状。PPIs是最有效的内科治疗手段。对于非糜烂性反流病(NERD)患者,按需治疗较为适宜。有慢性咳嗽、喉炎和典型GERD症状的患者在排除非GERD病因后,应予PPI每天两次治疗。如有经验丰富的外科医师,GERD患者可行胃底折叠术。除临床试验外,GERD不应采用内镜治疗。结论:新的诊断方法和内镜治疗的作用有待进一步研究阐明。亚洲GERD诊断策略的制定须考虑到并存的胃癌和消化性溃疡。PPIs仍为治疗的基石。 | Kwong Ming Fock Nicholas J Talley Ronnie Fass Khean Lee Goh Peter Katelaris Richard Hunt Michio Hongo Tiing Leong Ang Gerald Holtmann Sanjay Nandurkar San Ren Lin Benjamin CY Wong Francis KL Chan Abdul Aziz Rani Young-Tae Bak Jose Sollano Khek Yu Ho Sathoporn Manatsathit 钱本余 | 2008 | 胃肠病学2008，13，7： | 21 |
| 2 | Randomized,controlled trial of intramuscular or intracoronary injection of autologous bone marrow cells into scarred myocardium during CABG versus CABG alone显示文摘 | Ang KL Chin D Leyva F | | 0，，10： | 1 |
| 3 | Twenty months routine use of a new percutaneous tracheostomy set using controlled rotating dilation显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 4 | A non-radial DEA approach to measuring environmental performance 显示文摘 | P Zhou KL Poh BW Ang | 2007 | European Journal of Operational Research2007，，1： | 1 |
| 5 | Twenty months routine use of a new percutaneous tracheostomy set using controlled rotating dilation 显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 6 | Twenty months'routine use of a new percutaneons tracheostomy set using controlled rotatingdilation显示文摘 | Sengupta N Ang KL Prakash D etal | 2004 | Anesth Analg2004，，： | 1 |
| 7 | A trigonometric grey prediction approach to forecasting electricity demand 显示文摘 | P Zhou BW Ang KL Poh | 2006 | Energy2006，，31： | 1 |
| 8 | Reflex control of arterial pressure and heart rate in short-term streptozotocin diabetic rats显示文摘 | Dall'Ago P Silva VO De Angelis KL | 2002 | Braz J Med Biol Res2002，35，7： | 1 |
| 9 | Melkersson-Rosenthal syndrome显示文摘 | Ang KL Jones NS | 2002 | J Laryngol Otol2002，116，5： | 1 |
| 10 | Determination of lead in Smilax myosotiflora herbal preparations obtained in Malaysia显示文摘 | HH Ang KL Lee M. Kiyoshi | 2004 | International Journal of Environmental Health Research2004，，4： | 1 |
| 11 | Randomized,control ed trial of intramuscular or intracoronary injection of autologous bone marrow cells into scarred myocardium during CABG versus CABG alone显示文摘 | Ang KL Chin D Leyva F | | 0，，10： | 1 |
| 12 | Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracll 显示文摘 | de Angelis PM Fjdl B Kravik KL | 2004 | Int J Oncol2004，24，5： | 1 |
| 13 | Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention 显示文摘 | Ang KL Shi DL Keong WW | 2005 | Cancer Lett2005，225，1： | 1 |
| 14 | Twenty month's routine use of a new percutaneous tracheostomy set using conolled rotatingdilation显示文摘 | Ang KL Prakash D | 2004 | A nesth A nalg2004，99，1： | 1 |
| 15 | Twenty months' routine use of a new percutaneous tracheostomy set using controlled rotating dilation显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 16 | Measuring Environmental Performance under Different Environmental DEA Technologies 显示文摘 | Zhou P Ang B W Poh KL | 2008 | Energy Economics2008，30，： | 1 |
| 17 | Twenty months rou- tine use of a new percutaneous tracheostomy set using con- trolled rotating dilation 显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 18 | Twenty months' routine use of a new percutaneous traeheostomy set using controlled rotating dilation显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 19 | Twenty months routine use of a new percutaneous tracheostomy set using controlled rotating dilation显示文摘 | Sengupta N Ang KL Prakash D | 2004 | Anesth Analg2004，99，1： | 1 |
| 20 | Twenty months,routine use of a new percutaneous tracheostomy set using controlled rotating dilation显示文摘 | Sengupta N Ang KL Prakash D | | 0，，： | 1 |
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