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| 1 | Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury显示文摘The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited,especially in case of severe injury.This often leads to poor motor function and permanent disability.Existing approaches for the treatment of injured nerves do not provide appropriate conditions to support survival and growth of nerve cells.This drawback can be compensated by the use of gene therapy and cell therapy-based drugs that locally provide an increase in the key regulators of nerve growth,including neurotrophic factors and extracellular matrix proteins.Each growth factor plays its own specific angiotrophic or neurotrophic role.Currently,growth factors are widely studied as accelerators of nerve regeneration.Particularly noteworthy is synergy between various growth factors,that is essential for both angiogenesis and neurogenesis.Fibroblast growth factor 2 and vascular endothelial growth factor are widely known for their proangiogenic effects.At the same time,fibroblast growth factor 2 and vascular endothelial growth factor stimulate neural cell growth and play an important role in neurodegenerative diseases of the peripheral nervous system.Taken together,their neurotrophic and angiogenic properties have positive effect on the regeneration process.In this review we provide an in-depth overview of the role of fibroblast growth factor 2 and vascular endothelial growth factor in the regeneration of peripheral nerves,thus demonstrating their neurotherapeutic efficacy in improving neuron survival in the peripheral nervous system. | Kamilla Faritovna Idrisova Alina Kazymovna Zeinalova Galina Andreevna Masgutova Alexey Andreevich Bogov Jr. Cinzia Allegrucci Valeriia Yurievna Syromiatnikova Ilnur Ildusovich Salafutdinov Ekaterna Evgenievna Garanina Dina Ivanovna Andreeva Adilet Abdullaatovich Kadyrov Albert Anatolevich Rizvanov Ruslan Faridovich Masgutov | 2022 | Neural Regeneration Research2022，17，6： | 6 |
| 2 | 硅酸盐-盐(硫酸盐)流体不混溶:蒙古南部Mushugai-Khuduk含火成碳酸岩杂岩体矿物中的熔体包裹体研究显示文摘Crystalline and melt inclusions were studied in garnet,diopside,potassium feldspar,and sphene from the garnet syenite porphyry of the carbonatite-bearing complex Mushugai-Khuduk,southern Mongolia.Phlogopite,clinopyroxene,albite,potassium feldspar,spheric,wollastonite,magnetite,Ca and Sr sulfates,fluorite,and apatite were identified among the crystalline inclusions. The melt inclusions were homogenized at 1010~1080℃and analyzed on an electron microprobe.Silicate,salt,and combined silicate- salt melt inclusions were found.Silicate melts show considerable variations in SiO_2 concentration(56 to 66wt% ),high Na_2O+K_2O (up to 17wt% ),and elevated Zr,F,and C1 contents.In terms of bulk rock chemistry,the silicate melts are alkali syenites.During thermometric experiments,salt melt inclusions quenched into homogeneous glasses of predominantly sulfate compositions containing no more than 1.3wt% SiO_2.These melts are enriched in alkalis,Ba,Sr,P,F,and C1.The investigation of the silicate and salt melt inclusions in minerals of the garnet syenite porphyries indicate that these rocks were formed under influence of the processes of crystallization differentiation and magma separation into immiscible silicate and salt(sulfate)liquids. | Irina A. Andreeva Vyacheslav I. Kovalenko Vladimir B. Naumov | 2007 | 岩石学报2007，23，1： | 5 |
| 3 | Graphene and other two-dimensional materials显示文摘Over the last few years,research on graphene [1-3]has progressed significantly,and as a result,a number of reallife applications of graphene have been realized [4,5].This carbon allotrope (for a review on other forms of carbon, see [6])resulted in a number of novel physical phenomena already discovered (ranging from new types of quantum Hall effect to universal optical conductivity)and dramatically expanded the range of possible applications for such materials (from transparent conductive coating to ultrafast photodetectors). | Kostya S. Novoselov Daria V. Andreeva Wencai Ren Guangcun Shan | 2019 | Frontiers of physics2019，14，1： | 4 |
| 4 | Angiogenesis and nerve regeneration induced by local administration of plasmid pBud-coVEGF165-coFGF2 into the intact rat sciatic nerve显示文摘Vascular endothelial growth factor(VEGF) and fibroblast growth factor 2(FGF2) are well-known growth factors involved in the regeneration of various tissues and organs, including peripheral nerve system. In the present study, we elucidated the local and systemic effects of plasmid construct рBud-coVEGF165-coFGF2 injected into the epineurium of intact rat sciatic nerve. Results of histological examination of sciatic nerve and multiplex immunoassays of serum showed the absence of immunogenicity and biosafety of plasmid рBud-coVEGF165-coFGF2. Moreover, local administration of plasmid DNA construct resulted in significantly decreased levels of pro-inflammatory cytokines in the peripheral blood, including tumor necrosis factor α(TNFα) and interleukin-12, and significantly increased levels of cytokines and chemokines including Regulated upon Activation, Normal T Cell Expressed and Presumably Secrete(RANTES), epidermal growth factor, interleukin-2, and monocyte chemoattractant protein 1. These changes in the peripheral blood on day 7 after injection of plasmid construct рBud-coVEGF165-coFGF2 show that the plasmid construct has systemic effects and may modulate immune response. At the same time, reverse transcriptionpolymerase chain reaction revealed transient expression of coFGF2, coVEGF165, ratFGF2 and ratVEGFA with direct transport of transcripts from distal part to proximal part of the sciatic nerve. Immunohistochemical staining revealed prolonged presence of VEGFA in sciatic nerve till 14 days post-injection. These findings suggest that local administration of plasmid construct рBud-coVEGF165-coFGF2 at a concentration of 30 ng/μL results in the formation of pro-angiogenic stimuli and, and the plasmid construct, used as a drug for gene therapy, might potentially facilitate regeneration of the sciatic nerve. The study was approved by the Animal Ethics Committee of Kazan Federal University, procedures were approved by the Local Ethics Committee(approval No. 5) on May 27, 2014. | Ruslan Masgutov Alina Zeinalova Alexey Bogov Galina Masgutova Ilnur Salafutdinov Ekaterina Garanina Valeriia Syromiatnikova Kamilla Idrisova Adelya Mullakhmetova Dina Andreeva Liliya Mukhametova Adilet Kadyrov Igor Pankov Albert Rizvanov | 2021 | Neural Regeneration Research2021，16，9： | 3 |
| 5 | Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria显示文摘 | Panov A V Andreeva L Greenamyre JT | 2004 | Arch Biochem Biophys2004，424，1： | 1 |
| 6 | Synthesis and Antituberculosis Activity of Derivatives of Stevia rebaudiana Gly- coside Steviolbioside and Diterpenoid Isosteviol Containing Hydrazone, Hydrazide, and Pyridinoyl Moieties 显示文摘 | Kataev V Strobykin I Y Andreeva O V etc | 2011 | Russian Journal of Bioorganic Chemistry2011，37，4： | 1 |
| 7 | Apigenin Inhibits Growth of Breast Cancer Cells: The Role of ERa and HER2/neu显示文摘 | Scherbakov A M Andreeva O E | 2015 | Acta Naturae2015，7，3： | 1 |
| 8 | Thermalcharacteristic of para-aramid fibers显示文摘 | Perepelkin K E Andreeva I V Pakshver E A | 2003 | Fiber Chemistry2003，35，4： | 1 |
| 9 | Elimination of marker genes from transformed filamentous fungi by unselected transient transfec- tion with a Cre-expressing plasmid 显示文摘 | Florea S Andreeva K Machado C | 2009 | Fungal Genetics and Biology2009，46，10： | 1 |
| 10 | The neuroprotective effects of semax in conditionsof MPTP-induced lesions of the brain dopaminergic system显示文摘 | LEVITSKAYA N G SEBENTSOVA E A ANDREEVA L A | 2004 | Neurosci Behav Physiol2004，34，4： | 1 |
| 11 | SP22D:a multidomain serine protease with a putative role in insect immunity显示文摘 | Gorman MJ Andreeva OV Paskewitz SM | 2000 | Gene2000，251，1： | 1 |
| 12 | Pos sibilities of the Near-space Environment Radio Tomography显示文摘 | Kunitsyn V E Andreeva E S Razinkov O G | 1997 | Radio Science1997，32，5： | 1 |
| 13 | Characterization and Photocatalytic Activity of Au/TiO2 Thin Films for Azo - dye Degradation 显示文摘 | Arabatzis I M Stergiopoulos T Andreeva D | 2003 | Journal of Catalysis2003，，220： | 1 |
| 14 | Enzyme - linked immunosorbent assay of chlorampenicol in foodstuff显示文摘 | Fedorova M Andreeva I Vilegzhanina E | 2010 | Applied Biochemistry and Microbiology2010，46，8： | 1 |
| 15 | Local particle densities and global multiplicities in central heavy ion interactions at 3.7, 14.6, 60 and 200A GeV显示文摘 | M. I. Adamovich M. M. Aggarwal Y. A. Alexandrov N. P. Andreeva Z. V. Anson R. Arora F. A. Avetyan S. K. Badyal E. Basova K. B. Bhalla A. Bhasin V. S. Bhatia V. G. Bogdanov V. I. Bubnov T. H. Burnett X. Cai I. Y. Chasnikov L. P. Chernova M. M. Chernyavsky | 1992 | Zeitschrift für Physik C Particles and Fields1992，，4： | 1 |
| 16 | Support vector regression for loss given default modelling显示文摘 | Yao X Crook J Andreeva G | 2015 | European Journal of Operational Research2015，240，2： | 1 |
| 17 | A comparative study of nanosized IB/ceria catalysts for low-temperature water-gas shift reaction显示文摘 | TABAKOVA T BOCCUZZI F MANZOLI M SOBCZAKD J W IDAKIEVA V ANDREEVA D | 2006 | Appl Catal A2006，298，： | 1 |
| 18 | Low-temperature water-gas shift reaction on Auα-Fe2O3catalyst显示文摘 | Andreeva D Idakiev V Tabakova T | 1996 | Applied Catalysis A:General1996，134，2： | 1 |
| 19 | Sp22D: a multidomain serine protease with a putative role in insect immunity显示文摘 | Gorman MJ Andreeva OV Paskewitz SM | 2000 | Gene2000，251，1： | 1 |
| 20 | Iron-basedcatalystsforthewater-gasshiftreactionpromotedbyfirst-rowtransitionmetaloxides显示文摘 | AndreevA IdakievV MihajlovaD etal | 1986 | ApplCatal1986，22，： | 1 |
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