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| 1 | A Short Amino-Terminal Part of Arabidopsis Phytochrome A Induces Constitutive Photomorphogenic Response显示文摘Phytochrome A (phyA ) 是在 Arabidopsis thaliana 察觉到的 far-red 光的主导的光敏电阻器。phyA 在发信号的变白的幼苗,和导致光的 phyA 的细胞质在高水平积累被一个复杂规章的网络调停。这包括光 -- 并且进在 vivo 的原子核的本国的 phyA 的 FHY1/FHL 蛋白质依赖者 translocation。phyA (PHYA406 ) 的短 N 终端碎片对 phenocopy 足够,这也被显示出在 vitro 的这个高度调整的细胞的过程。为了测试这 N 终端的生物活动,在 planta phyA 碎裂,我们生产了表示 PHYA406YFP 的转基因的 phyA-201 植物(黄荧光灯蛋白质) DD, PHYA406YFPDDNLS (原子本地化信号) ,和 PHYA406YFPDDNES (原子出口信号) 熔化蛋白质。这里,我们报导 PHYA406YFPDD 被进口进原子核,而 PHYA406YFPDDNLS 和 PHYA406YFPDDNES 显示期望的组成的本地化模式,这进程部分是轻依赖者的。我们的结果证明这些截断的 phyA 蛋白质是轻马厩的,当局部性时,他们在他们的原子核,和两个都不触发组成的象 photomorphogenic 一样回答导致合适的 phyA 发信号。我们证明在 vitro 并且在 vivo PHYA406, Pfr 和 Pr 绑 COP1, photomorphogenesis 的一个一般抑压者,并且在原子身体与它共同本地化。因此,我们断定在 planta,截断的 PHYA406 蛋白质以一种光无关的方式在原子核使 COP1 失去活性。 | Andra's Viczia'n E'va Ada'm Iris Wolf Ja'nos Bindics Stefan Kircher Marc Heijde Roman Ulm Eberhard Scha'fer Ferenc Nagy | 2012 | Molecular Plant2012，5，3： | 2 |
| 2 | Developing rat testicular organoid models for assessing the reproductive toxicity of antidepression drugs in vitro显示文摘With the increasing incidence of depression worldwide,antidepressant medications are commonly used in males of reproductive age for long-term treatment of depression,as well as other disorders[1].Antidepressants are known to be associated with sexual side effects[2],such as decreased libido and impotence.Their effects on semen parameters and other markers of male fertility have been less thoroughly described,such as sperm motility and fertilization ability.Therefore,it is critical to determine the potential toxic effects of antidepressants on reproductive organs.A recent study systemically determined the effect of different drugs on the telomere-related DNA damage response of germ cells[3].In addition,another study showed that mirtazapine has less toxic effects than amitriptyline and other drugs[4].However,these studies used germ cell lines to determine the phenotype,which limits their potential translational value in toxicity studies in humans.Given the widespread and often long-term use of antidepressant medications,there is an urgent need for further data regarding their impact on semen quality and subsequent male fertility. | Sixian Wu Xiaoliang Li Peiyu Li Tongtong Li Gelin Huang Qun Sun Andras Dinnyés Lijun Shang Wenming Xu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 1 |
| 3 | Image change detection algorithms: A systematic survey显示文摘 | Radke R J Andra S Alkofahi O | 2005 | Image Processing IEEE Trans- actions on2005，14，3： | 1 |
| 4 | Fenoxycarb levels and their effects on general and juvenile hormone esterase activity in the hemolymph of the silkworm,Bombyx mori显示文摘 | Skarlatos G D Ferenc S Andras S | 2003 | Pesticide Biochemistry and Physiology2003，73，： | 1 |
| 5 | Chelant-aided Enhancement of Lead Mobilization in Residential Soils显示文摘 | Sarkar D Andra S S Saminathan S K M | 2008 | Environmental Pollution2008，156，： | 1 |
| 6 | An Analysis of 8305 Cases of Carcinoid Tumors显示文摘 | Irvin M M Andras S | 1997 | Cancer1997，79，9： | 1 |
| 7 | Preharvest tenderization oral calcium gel administration显示文摘 | Ducket S K Klein T A Andrae J G | 1998 | Anim Sci1998，76，： | 1 |
| 8 | Using the h-index for assessing single publication 显示文摘 | Andras S | 2009 | Scientometrics2009，78，3： | 1 |
| 9 | Effects of feeding high-oil corn to beef streers on carcass characteristic and meat quality显示文摘 | ANDRAE J G DUCKETT S K HUNT C W | 2001 | Journal of Animal Science2001，79，3： | 1 |
| 10 | Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces显示文摘 | Elena Scarpa Andra s Szabo | 2015 | Developmental Cell 342015，34，4： | 1 |
| 11 | Kinematics and Workspaee Modeling of a New Hybrid Robot Used in Minimally Invasive Surgery 显示文摘 | Doina P Andras S Calin V | 2013 | Robotics and Computer- Integrated Manufacturing2013，29，2： | 1 |
| 12 | Varma显示文摘 | Jozsef Dudas Judit Toth and Rajender S | 2001 | Tetrahedron Letter2001，42，： | 1 |
| 13 | Image Change Detection Algorithms:a Systematic Survey显示文摘 | Radke R J Andra S Al-Kofahi O | 2005 | IEEE Transactions on Image Processing2005，14，3： | 1 |
| 14 | Evidence of arsenic release promoted by disinfection by-products within drinking-water distribution systems显示文摘 | Andra S S Makris K C Botsaris G | 2014 | Science of the Total Environment2014，472，： | 1 |
| 15 | Summer forage species alters animal performance,carcass characteristics and fatty acid omposition of grazing beef steers显示文摘 | Schmidt J R Andrae J G Duckett S K | 2009 | J Anim Sci E-Suppl 2 / J Dairy Sci2009，921，： | 1 |
| 16 | Allergy testing in children : why, who, when and how 显示文摘 | Host A Andrae S Charkin S | 2003 | Allergy2003，58，7： | 1 |
| 17 | Structural differences between mesophilic, moderately thermophilic and extremely thermophilic protein subunits: Results of a comprehensive survey显示文摘 | ANDRAS S PETER Z | 2000 | Structure2000，8，5： | 1 |
| 18 | Influence of glycation and pepsin hydrolysis immunoreaetivity of Albumin/globulin fraction of herbicide resistant wheat line显示文摘 | Andras N Marciniak Darmochwat K Krawczuk S | 2009 | Czech Journal of Food Sciences2009，27，5： | 1 |
| 19 | Chemical safety of meat and meat products 显示文摘 | Andrae S Jira W Schwind K H | 2010 | Meat Science2010，86，1： | 1 |
| 20 | Image Change Detection Algorithms: A Systematic Survey 显示文摘 | Radke R J Andra S Al-kofahi O | 2004 | Sensing And Imaging2004，132，： | 1 |
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