|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | WJSC 6^(th) Anniversary Special Issues(2):Mesenchymal stem cells Progress of mesenchymal stem cell therapy for neural and retinal diseases显示文摘Complex circuitry and limited regenerative power make central nervous system(CNS)disorders the most challenging and difficult for functional repair.With elusive disease mechanisms,traditional surgical and medical interventions merely slow down the progression of the neurodegenerative diseases.However,the number of neurons still diminishes in many patients.Recently,stem cell therapy has been proposed as a viable option.Mesenchymal stem cells(MSCs),a widely-studied human adult stem cell population,have been discovered for more than 20 years.MSCs have been found all over the body and can be conveniently obtained from different accessible tissues:bone marrow,blood,and adipose and dental tissue.MSCs have high proliferative and differentiation abilities,providing an inexhaustible source of neurons and glia for cell replacement therapy.Moreover,MSCs also show neuroprotective effects without any genetic modification or reprogramming.In addition,the extraordinary immunomodulatory properties of MSCs enable autologous and heterologous transplantation.These qualities heighten the clinical applicability of MSCs when dealing with the pathologies of CNS disorders.Here,we summarize the latest progress of MSC experimental research as well as human clinical trials for neural and retinal diseases.This review article will focus on multiple sclerosis,spinal cord injury,autism,glaucoma,retinitis pigmentosa and age-related macular degeneration. | Tsz Kin Ng Veronica R Fortino Daniel Pelaez Herman S Cheung | 2014 | World Journal of Stem Cells2014，6，2： | 13 |
| 2 | Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients显示文摘Background The true risk of choronic villus sampling (C VS) is poorly defined. The objective of this study was to review the clinical o utcome of transabdominal CVS performed in a university teaching unit, with an em phasis on the complication rate. Methods A comprehensive audit database was maintained for 1351 pregnant women, including 17 sets of twin pregnancies, who had a CVS. Details a nd outcome of all CVSs made in the unit between May 1996 and May 2004 were revie wed. All CVSs were performed by one of 5 operators using the identical techniqu es. Results All procedures were performed transabdominally. A tota l of 1355 CVSs were performed because there were 4 dichorionic twin pregnancies which required 2 punctures. The mean gestation at CVS was (11.8±0.7) weeks, and 97.3% of the procedures were performed between 11 and 13 completed weeks. The majority (96.2%) required only 1 puncture to achieve correct needle placeme nt. The procedure failed to obtain an adequate sample in 4 subjects (0.30%). A total of 1351 chromosomal studies were requested and there was 1 case (0.07%) of culture failure. The results of chromosomal studies were available within 1 4 days in 36.7% of the cases and within 21 days in 94.0%. Overall, 77 chromos omal abnormalities (5.7%) and 5 cases of thalassemia major were detected. Preg nancy outcome was unknown in only 13 singleton subjects (0.96%). In the remain ing 1355 fetuses, there were 76 pregnancy terminations (5.56%), 10 fetal losses with obvious obstetric causes (0.73%), and 21 potentially procedure-relat ed fetal losses (1.54%). In the last group, the majority had one or more co-e xisting obstetric complications. The background fetal loss rate for pregnancies at similar gestational age in the unit was about 0.8%. Therefore, the procedu re-related fetal loss rate was estimated to be at the maximum of 0.74%. Conclusions In experienced hands, first trimester transabdomina l CVS is an accurate and safe invasive prenatal diagnostic procedure. It should be one of the treatment options available to pregnant women who require prenata l genetic diagnosis. | LAU Tze Kin LEUNG Tak Yeung FUNG Tak Yuen Daljit S SAHOTA LEUNG Tse Ngong | 2005 | Chinese Medical Journal2005，，20： | 8 |
| 3 | On the macroparticle flux from vacuum arc cathode spots显示文摘 | Anders S Anders A Kin M Y | 1993 | IEEE Trans On Plasma Science1993，21，： | 2 |
| 4 | 电脑比色仪与比色板比色间的相关性及其差异显示文摘目的分析电脑比色与视觉比色的相关性及其差异。方法采用ShadeVision牙比色仪和Vitapan Classical比色板分别对120例健康志愿者上颌前牙漂白前及漂白后10d、20d、3个月及6个月进行比色。ShadeVision牙比色仪分别对牙冠切1/3、中1/3、龈1/3进行比色,并与Vitapan Classical比色板比色结果相比较,统计两者间的异同比例,并采用Spearman秩相关检验进行统计分析。结果对整个牙冠比色的5个不同时期中,两种方法的相关系数分别为0.723、0.739、0.682、0.705、0.730;相关系数最高的是视觉比色与比色仪对整个牙冠和牙冠中1/3的比色,而最低的是视觉比色与比色仪对牙冠龈1/3的比色。比色结果一致的比例为19.6%~340%,≤2个色阶差别的比例为51.5%~71.0%,≤1个色阶差别的比例为410%~58.4%;漂白前两种方法存在4个色阶差的比例为20.3%,而漂白后仅为0.4%~0.8%,一致性比例较漂白前有所提高。结论电脑比色和视觉比色间既存在正相关关系,也存在差异,临床应用时应合理选择,亦可结合使用。 | 陈宏 黄建静 W Zhang S Lee 张秀华 J Kin 李一鸣 | 2009 | 浙江医学2009，31，1： | 2 |
| 5 | Comparative radiation impact on biota and man in the area affected by the accident at the Chernobyl nuclear power plant显示文摘 | ALEXAKHIN R M GERAS′KIN S A | 2005 | J Environ Radioact2005，80，： | 1 |
| 6 | A new distributed location management algorithm for broadband personal communication networks显示文摘 | KIN B C CHOI J S UN C K | 1995 | IEEE Transactions on Vehicular Technology1995，44，3： | 1 |
| 7 | Growth of Zinc Selenide Single Crystal by the Modified Piper and Poshch Sublimation Method显示文摘 | Lee H Kim T S Jeong T S An H G Kin J Y | 1998 | Journal of Crystal Growth1998，191，： | 1 |
| 8 | The HTK solution with Nicorandil can improve function after simple cold storage显示文摘 | Kin S Saiton Y | 1996 | Transplantation Proceedings1996，28，： | 1 |
| 9 | Case study on rate-based traffic control of industrial networks employing Lonworks显示文摘 | Kin B H Park K S | 2002 | International Journal of Systems Science2002，33，3： | 1 |
| 10 | A new method for solving equilibrium problem fixed point problem and Variational inequality problem with application to optimization显示文摘 | Chang S S Joseph Lee H W Chan Chi Kin | 2009 | Nonlinear Anal:TMA2009，70，9： | 1 |
| 11 | Biomechanical evaluation of kyphoplasty and vertebroplasty with calcium phosphate cement in a simulated osteoporotic compression fracture显示文摘 | Tomita S Kin A Yazu M | | 0，，02： | 1 |
| 12 | An orally administered mul- titarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibi- tor of thyroid oneogenie RET/papillary thyroid cancer kinases 显示文摘 | KIN D W JOY S JUNG H S | 2006 | J Clin Endocrinol Metab2006，91，10： | 1 |
| 13 | Automatic ontologybased knowledge extraction from Web documents 显示文摘 | ALANI H KIN S MILLARD D E | 2003 | IEEE Computer Society2003，，1： | 1 |
| 14 | High temperature deformation behavior of a γ-TiAl alloy determined using the load-relaxation test 显示文摘 | KIN/J H HA T K CHANG Y W LEE C S | 2003 | Materials Science and Engineering A2003，344，： | 1 |
| 15 | Pulsed laser deposition of BaTiO3 thin films and their optical properties显示文摘 | Kin D H Kwork H S | 1995 | Appl Phys Lett1995，67，13： | 1 |
| 16 | Drug discovery from natural products显示文摘 | Vincent P G James M Kin S L | 2006 | J Ind Microbiol Biotechnol2006，33，7： | 1 |
| 17 | Discovery of novel metabolites from marine actinomyctes显示文摘 | Kin S L | | 0，，03： | 1 |
| 18 | Synthesis of Triazine-Based Polyimide Nanocomposites with Flower-Like ZnO by Microwave-Assisted Solvothermal Technique显示文摘 | Turgay Se?kin Nilufer K?v?lc?m Süleyman K?ytepe | 2013 | Polymer-Plastics Technology and Engineering2013，，13： | 1 |
| 19 | Mechanisms of edema formation after intracerebral hemorrhage: effects of thrombin on cerebral blood flow, blood-brain barrier permeability and cerebral in a rat model 显示文摘 | Kawal N Kin S | 1997 | J Neurosurg1997，86，2： | 1 |
| 20 | The effect of hydrogen peroxide on a CST under cesium ion exchange conditions显示文摘 | KIN S H PHILIP M ANTHONY R G | 2003 | Separation Science and Technology2003，38，1213： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员