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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | Endoscopic treatment modalities and outcomes in nonvariceal upper gastrointestinal bleeding显示文摘BACKGROUND In nonvariceal upper gastrointestinal bleeding(NVUGIB),the optimal volume of adrenaline,the optimal number of hemoclips,and the application of thermal coagulation in determining patient outcomes have not been well studied.AIM To demonstrate a dose-response relationship between the commonly used endoscopic modalities for the treatment of non-variceal upper gastrointestinal bleeding and various clinical outcomes.METHODS Patients presenting with NVUGIB were retrospectively identified and analyzed.These patients were stratified as follows:(1)>10 mL of adrenaline injected vs≤10 mL;(2)>1 hemoclip placed vs≤1 hemoclip;(3)Heater probe used or not;and(4)>2 treatment modalities used vs≤2.The primary outcomes were rebleeding and the need for repeat endoscopy.The secondary outcomes were the need for surgery,required transfusions,length of hospital stay,death during the same admission period and 30 d mortality.Patients with NVUGIB who required endoscopic therapy were included.Those who did not require endoscopic therapy or were initially treated with surgery or embolization were excluded.RESULTS In all,501 patients with NVUGIB were treated.One hundred sixty-one(32.1%)patients needed endoscopic therapy.The injection of<10 mL of adrenaline was associated with less rebleeding(P<0.0001),the need for repeat endoscopy(P=0.001)and a decreased length of hospital stay(P=0.026).The use of>2 treatment modalities were associated with increased rebleeding(P=0.009)and the need for repeat endoscopy(P=0.048).The placement of>1 hemoclip was associated with a decreased length of hospital stay(P=0.044).The rates of surgery and death were low,and there were no other significant differences between the patient groups.CONCLUSION The more restrictive use of adrenaline and number of endoscopic modalities to treat NVUGIB with the more liberal use of hemoclips was associated with better patient outcomes. | Benjamin Cherng Hann Yip Hossain Sayeed Sajjad Jie-Xun Wang Constantinos P Anastassiades | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，2： | 2 |
| 3 | Modulation of mitogendependent lymphocyte stimulation by hyaluronic acid显示文摘 | Anastassiades T Robertson W | 1984 | J Rheumatol1984，11，6： | 1 |
| 4 | Development and independent laboratory validation of a simple method for the determination of paraquat and diquat in potato, cereals and pulses显示文摘 | Kolberg D I Mack D Anastassiades M | 2012 | Anal Bioanal Chem2012，404，8： | 1 |
| 5 | Analysis of carbendazim, benomyl, thiophanate methyl and 2, 4-dichlorophenoxy acetic acid in fruits and vegetables after supercritical fluid extraction显示文摘 | Anastassiades M Schwack W | 1998 | Journal of Chromatography A1998，825，1： | 1 |
| 6 | 查看详情显示文摘 | Anastassiades M Lehotay S J Stajnbaher D Schenck F J | | 0，，02： | 1 |
| 7 | Development, validation, and application of an acetylcholinesterase-biosensor test for the direct detection of insecticide residues in infant food显示文摘 | Schulze H Scherbaum E Anastassiades M | 2002 | Biosensors and Bioelectronics2002，17，： | 1 |
| 8 | Fast and easy multiresidue method employing acetonitrile extraction! partitioning and dispersive solid-phase extraction for the determination of pesticide residues in produce显示文摘 | Anastassiades M Lehotay SJ Stajnbaher D | 2003 | Journal of aoac international2003，86，2： | 1 |
| 9 | Fast and easy multiresidue method employing acetonitrile extraction/partitioning and“dispersive solid-phase extraction”for the determination of pesticide residues in produce显示文摘 | ANASTASSIADES M LEHOTAY S J 譒TAJNBAHER D | 2003 | Journal of AOAC International2003，86，2： | 1 |
| 10 | Combination of analyte protectants to overcome matrix effects in routine GC analysis of pesticide residues in food matrixes显示文摘 | MASTOVSKA K LEHOTAY S J ANASTASSIADES M | 2005 | Anal Chem2005，77，24： | 1 |
| 11 | Fast and easy multiresidue method employing acetonitrile extraction/partitioning and 'dispersive solid-phase extraction' for the determination of pesticide residues in produce显示文摘 | M Anastassiades S J Lehotay D Stajnbaher | 2003 | J AOAC Int2003，86，2： | 1 |
| 12 | Fast and easymultiresidue method employing acetonitrile extraction/partitioningand“dispersive solid-phase extraction”for the determination ofpesticide residues in produce显示文摘 | Anastassiades M Lehotay S J Stajnbaher D | 2003 | Journal of AOAC International2003，86，2： | 1 |
| 13 | Development, validation, and application of an acetylcholinesterase biosensor test for the direct detection of insecticide residues in infant food 显示文摘 | Schulze H Scherbaum E Anastassiades M | 2002 | Bachmann Biosensors and Bioelectronics2002，17，： | 1 |
| 14 | Fast and easy muhiresidue method employing acetonitrile extraction/ partitioning and 'dispensive solid-phase extraction' for the determination of pesticide residues in produce 显示文摘 | ANASTASSIADES M LEHOTAY S J STAJNBAHER D | 2007 | J Rapid Conmmn Mass Spectrom2007，21，： | 1 |
| 15 | Fast and Easy Multiresidue Method Employing Aeetonitrile Extration/Partitioning and 'Dispersive Soild-phase Extraction' for the Determination of Pesticide Residue in Produce 显示文摘 | ANASTASSIADES M LEHOTAY S J STAJNBAHER D | 2003 | J AOAC Int2003，86，41： | 1 |
| 16 | Fast and easy multiresidue method employing acetonitrile extraction/partitioning and 'dispersive solid-phase extraction' for the determination of pesticide residues in produce显示文摘 | ANASTASSIADES M LEHOTAY S J STAJNBAHER D SCHENCK F J | 2003 | J AOAC Int2003，86，9： | 1 |
| 17 | Fast and easy multiresidue method employing acetonitrile extraction/partitioning and 'dispersive solid-phase extraction' for the determination of pesticide residues in produce显示文摘 | ANASTASSIADES M LEHOTAY S J | 2003 | J AOAC Int2003，86，2： | 1 |
| 18 | Fast and easy multiresidue method employing acetonitrile extraction/partitioning and ' dispersive solid - phase extraction' for the determination of pesticide residues in produce 显示文摘 | Anastassiades M Lehotay SJ Stajnbaher D | 2003 | J AOAC International2003，86，2： | 1 |
| 19 | Fast andeasy multiresidue method employing acetonitrile extraction/partitioning and “ dispersive solid - phase extraction ’’ for thedetermination of pesticide residues in produce 显示文摘 | Anastassiades M Lehotay S J Stajnbaher D | 2003 | J AOAC Int2003，86，2： | 1 |
| 20 | Analysis of carbendazim,benomyl,thiophanate methyl and 2,4-dichlorophenoxyacetic acid in fruits and vegetables after supercritical fluid extraction显示文摘 | ANASTASSIADES M SCHWACK W | | 0，，01： | 1 |
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