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| 1 | C-reactive protein and diabetic retinopathy in Chinese patients with type 2 diabetes mellitus显示文摘AIM:To investigate the relationship between Creactive protein(CRP)and diabetic retinopathy(DR)in a cohort of Chinese patients with type 2 diabetes mellitus(T2DM).·METHODS:Community-based observational cohort study.There were 1131 participants recruited from November 2009 to September 2011 in Desheng community in urban Beijing.Patients diagnosed T2DM were recruited and underwent a standardized evaluation consisting of a questionnaire,ocular and anthropometric examinations and laboratory investigation.The presence and severity of DR were assessed by seven fields 30°color fundus photographs.Subjects were then classified into groups with no DR,any DR,or vision-threatening DR.CRP was analyzed from serum of study subjects.·RESULTS:A total of 1007 patients with T2DM were included for analysis,including 408(40.5%)men and 599(59.5%)women.The median CRP level was 1.5 mg/L for women and 1.1 mg/L for men(P=0.004,OR 0.37,95%CI0.18-0.74).After adjusting for possible covariates,higher levels of CRP were associated with lower prevalence of any DR(P=0.02,OR 0.55,95%CI 0.35-0.89),but not associated with vision-threatening DR(P=0.62,OR 0.78,95%CI 0.28-2.14).After stratification by sex,the inverseassociation between CRP and DR was found to be statistically significant in men(P=0.006,OR 0.35,95%CI0.16-0.73),but not in women(P=0.58,OR 0.88,95%CI0.29-1.16).·CONCLUSION:The data drawn from a Chinese population with T2DM suggest that increasing CRP levels may be inversely associated with development of DR. | Xiu-Fen Yang Yu Deng Hong Gu Apiradee Lim Torkel Snellingen Xi-Pu Liu Ning-Li Wang Amitha Domalpally Ronald Danis Ning-Pu Liu | 2016 | International Journal of Ophthalmology(English edition)2016，9，1： | 6 |
| 2 | A Non-aqueous Electrolyte-based Asynunetric Supercapacitor with Polymer and Metal Oxide/multiwalled Carbon Nanotube Electrodes显示文摘 | Amitha F E Reddy A L M Ramaprabhu S | 2009 | Journal of Nanoparticle Research2009，11，3： | 1 |
| 3 | Asymmetric flexible supercapacitor stack显示文摘 | Reddy A L M Amitha F E Jafri I | 2008 | Nanoscale Res Lett2008，，3： | 1 |
| 4 | Synthesis of zinc oxide porous structures by anodization with water as an electrolyte显示文摘 | Amitha Shetty Karuna Kar Nanda | 2012 | Applied Physics A2012，，1： | 1 |
| 5 | Anticancer activity of C arica papaya : A review显示文摘 | Thao T. T. Nguyen Paul N. Shaw Marie‐Odile Parat Amitha K. Hewavitharana | 2012 | Mol Nutr Food Res2012，，1： | 1 |
| 6 | Antibiogram profile based dendrogram analysis of Escherichia coli serotypes isola- ted from bovine mastitis显示文摘 | Sumathi B R Amitha R G Krishnappa G | 2008 | Vet World2008，1，2： | 1 |
| 7 | Vitamin D levels and disease status in texas patients with systemic lupus erythematosus显示文摘 | THUDI AMITHA MBBS YIN SU M D | 2008 | Am J Med Sci2008，335，2： | 1 |
| 8 | Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction显示文摘 | Tae KK Amitha KH Shaw PN | 2006 | Applied and Envirunmental Microbiology2006，72，3： | 1 |
| 9 | Problematic eating and its association with early childhood caries among 46- 71 - month- old children using Children's Eating BehaviorQuestionnaire (CEBQ): A cross sectional study 显示文摘 | Latha Anandakrishna Neha Bhargav Amitha Hegde | 2014 | Indian J Dent Res2014，25，5： | 1 |
| 10 | Repeatability of Retinal Thickness Measurements Between Spectral-Domain and Time-Domain Optical Coherence Tomography Images in Macular Disease显示文摘 | Domalpally Amitha Gangaputra Sapna Peng Qian Danis Ronald P | 2010 | Ophthalmic Surgery Lasers and Imaging2010，，6： | 1 |
| 11 | Aayutha系列桌椅设计,致敬古老石雕艺术显示文摘Aayutha系列桌椅借鉴了泰米尔语的历史和文化,公元前400年的Sangam时期,印度蓬勃发展,泰米尔语文字由此诞生。这张桌子将黑色平板桌面和灰色花岗岩桌腿并置,以纪念Mamallapuram的石雕艺术。椅子除了黄铜饰面外,还采用编织皮革和纸绳靠背,带来奢华的饰面,底部的隐藏式轮子更便于使用。 | Amitha Agrim | 2024 | 工业设计2024，，2： | 0 |
| 12 | Genome-Wide Analysis of von Willebrand Factor A Gene Family in Rice for Its Role in Imparting Biotic Stress Resistance with Emphasis on Rice Blast Disease显示文摘von Willebrand factor A(vWA)genes are well characterized in humans except for few BONZAI genes,but the vWA genes are least explored in plants.Considering the novelty and vital role of vWA genes,this study aimed at characterization of vWA superfamily in rice.Rice genome was found to have 40 vWA genes distributed across all the 12 chromosomes,and 20 of the 40 vWA genes were unique while the remaining shared large fragment similarities with each other,indicating gene duplication.In addition to vWA domain,vWA proteins possess other different motifs or domains,such as ubiquitin interacting motif in protein degradation pathway,and RING finger in protein-protein interaction.Expression analysis of vWA genes in available expression data suggested that they probably function in biotic and abiotic stress responses including hormonal response and signaling.The frequency of transposon elements in the entire 3K rice germplasm was negligible except for 9 vWA genes,indicating the importance of these genes in rice.Structural and functional diversities showed that the vWA genes in a blast-resistant rice variety Tetep had huge variations compared to blast-susceptible rice varieties HP2216 and Nipponbare.qRT-PCR analysis of vWA genes in Magnaporthe oryzae infected rice tissues indicated OsvWA9,OsvWA36,OsvWA37 and OsvWA18 as the optimal candidate genes for disease resistance.This is the first attempt to characterize vWA gene family in plant species. | Suhas Gorakh KARKUTE Vishesh KUMAR Mohd TASLEEM Dwijesh Chandra MISHRA Krishna Kumar CHATURVEDI Anil RAI Amitha Mithra SEVANTHI Kishor GAIKWAD Tilak Raj SHARMA Amolkumar U.SOLANKE | 2022 | Rice science2022，29，4： | 0 |
| 13 | Exosomes: Emerging implementation of nanotechnology for detecting and managing novel corona virus-SARS-CoV-2显示文摘The spread of SARS-CoV-2 as an emerging novel coronavirus disease (COVID-19) had progressed as a worldwide pandemic since the end of 2019. COVID-19 affects firstly lungs tissues which are known for their very slow regeneration. Afterwards, enormous cytokine stimulation occurs in the infected cells immediately after a lung infection which necessitates good management to save patients. Exosomes are extracellular vesicles of nanometric size released by reticulocytes on maturation and are known to mediate intercellular communications. The exosomal cargo serves as biomarkers in diagnosing various diseases;moreover, exosomes could be employed as nanocarriers in drug delivery systems. Exosomes look promising to combat the current pandemic since they contribute to the immune response against several viral pathogens. Many studies have proved the potential of using exosomes either as viral elements or host systems that acquire immune-stimulatory effects and could be used as a vaccine or drug delivery tool. It is essential to stop viral replication, prevent and reverse the massive storm of cytokine that worsens the infected patients’ situations for the management of COVID-19. The main benefits of exosomes could be;no cells will be introduced, no chance of mutation, lack of immunogenicity and the damaged genetic material that could negatively affect the recipient is avoided. Additionally, it was found that exosomes are static with no ability for in vivo reproduction. The current review article discusses the possibilities of using exosomes for detecting novel coronavirus and summarizes state of the art concerning the clinical trials initiated for examining the use of COVID-19 specific T cells derived exosomes and mesenchymal stem cells derived exosomes in managing COVID-19. | Akhilesh Dubey Cynthia Lizzie Lobo Ravi GS Amitha Shetty Srinivas Hebbar Sally AEl-Zahaby | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，1： | 0 |
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