维普中文期刊产品整合服务
1269篇 您的检索式:作者名="Alvarez P"
    题名 作者 年代 出处 被引量
1Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages.Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta 2017Asian Pacific Journal of Tropical Biomedicine2017,7,3:3
2PPARγ promptes monocyte/macrophage differentiation and uptake of oxidized LDL显示文摘Tontonoz P Nagy L Alvarez JGA 1998Cell1998,93,2:2
3Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR gamma显示文摘Nagy L Tontonoz P Alvarez JG 1998Cell1998,93,2:2
4Reactive oxygen interme- diates mediate a systemic signal network in the establishment of plant immunity显示文摘Alvarez M Pennell R Meijer P 1998Cell1998,92,6:1
5Activated carbon adsorption of some phenofic compounds present in agroindustrial wastewater显示文摘Garcia-Araya J F Beltran F J Alvarez P 2003Adsorption2003,9,2:1
6Preparation and structural characterization of Co/AI2 03 catalysts for the ozonation of pyruvic acid 显示文摘ALVAREZ P M BELTRAN F J POCOSTALES J P 2007Applied Catalysis B: Environmental2007,72,34:1
7Alterations ofdopaminergic and noradrenergic innerrations in mortor cortex inParkinson's disease显示文摘Gaspar P Puyckaerts C Alvarez C 1991Ann Neurol1991,30,:1
8Rapid detection of herpes simplex virus DNA in genital ulcers by real-time PCR using SYBR green I dye as the detection signal 显示文摘Aldea C Alvarez C P Folgueira L 2002J Clin Microbiol2002,40,3:1
9Determination of organic acids in grape musts, wines and vinegars by high performance liquid-chromatography显示文摘ROMERO E G MUNOZ G S ALVAREZ P J M 1993Journal of Chromatography A1993,655,1:1
10Changes in polyamines, proline and ethylene in sunflower calluses treated with NaCl 显示文摘Alvarez I Tomaro M L Benavides M P 2003Plant Cell Tissue Organ Cult2003,74,:1
11Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-Ⅲ by obestatin显示文摘Pazos Y Alvarez C J Camia J P Casanueva F F 2007Growth Factors2007,25,6:1
12International autoimmune hepatitis group report:review of criteria for diagnosis of autoimmune hepatitis显示文摘ALVAREZ F BERG P A BIANCHI F B 1999J Hepatol1999,31,5:1
13Ozonation of activated carbons: Effect on the adsorption of selected phenolic compounds from aqueous solutions 显示文摘ALVAREZ P M GARCIA-ARAYA J F BELTRAN F J 2005J Colloid Interf Sci2005,283,2:1
14Reactive oxygen intermediates mediate a systemic signal network in the establishment of plant immunity显示文摘Alvarez M E Pennell R I Meijer P J 1998Cell1998,92,:1
15Image selective smoothing and edge detection by nonlinear diffusion II 显示文摘ALVAREZ L LIONS P L MOREL J M 1992SIAM Journal of Numerical Analysis1992,29,3:1
16Percutaneous vertebroplasty: long-term clinical and radiological outcome显示文摘A. Pérez-Higueras L. Alvarez R. Rossi D. Qui?ones I. Al-Assir 2002Neuroradiology2002,,11:1
17Anaerobic digestion of organicsolid wastes:Anoverview of research achievements and perspectives显示文摘Alvarez J M Macés L P 0,,74:1
18Ring opening of 1,2 - and1,3- dimethylcyclohexane on iridium catalysts 显示文摘Do P T Alvarez W E f Resasco D E 2006Journal ofCatalysis2006,238,2:1
19Oxidized LDL regulates maerophage gene exression through ligand aetivation of PPARa显示文摘Nagy L Tontonoz P Alvarez JGA 1998Cell1998,93,2:1
20Effect of pH on injection phlebitis显示文摘 Pinsuwan S Alvarez JM 1995J Pharm Sci1995,84,:1
返回顶部 每页显示:
共64页 首页 上一页 第1页 下一页 末页 /64 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费