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| 1 | High adiponectin levels fail to protect against the risk of hypertension and,in women,against coronary disease:involvement in autoimmunity?显示文摘AIM:To investigate whether serum adiponectin protects against cardiometabolic risk in a population sample with prevailing metabolic syndrome.METHODS:Middle-aged adults representative of a general population with baseline circulating adiponectin measurements(n=1224)were analyzed prospectively at a mean of 3.8 years’follow-up,using continuous values or sex-specific tertiles.Total adiponectin was assayed by an ELISA kit.Type-2 diabetes was identified by criteria of the American Diabetes Association.Hypertension was defined as a blood pressure≥140 mmHg and/or≥90 mmHg and/or use of antihypertensive medication.Outcomes were predicted using Cox proportional hazards regression analysis in models that were controlled for potential confounders.RESULTS:In models of multiple linear regression,sex hormone-binding globulin,fasting insulin(inverse)and,in men,age were significant independent covariates of serum adiponectin which further tended in women to be positively associated with serum creatinine.Cox regression analyses for incident coronary heart disease(CHD),adjusted for sex,age,non-HDL cholesterol,waist circumference and C-reactive protein,revealed significant inverse association with adiponectin tertiles in men but not women(HR=0.66;95%CI:0.32-1.38 for highest tertile).Cox regression for type-2 diabetes in a similar model(wherein glucose replaced non-HDL cholesterol),adiponectin tertiles appeared to protect in each gender.HR for incident hypertension roughly displayed unity in each of the adiponectin tertiles(P-trend=0.67).CONCLUSION:High adiponectin levels failed to protect against the development of hypertension and,in women,against CHD,presumably paralleling impairment in renal function as well.Involvement of adiponectin in autoimmune complex with loss of antioxidative-antiatherogenic properties may be underlying. | Altan Onat Mesut Aydln Günay Can Bayram Kroglu Ahmet Karagz Servet Altay | 2013 | World Journal of Diabetes2013，4，5： | 3 |
| 2 | Elevated serum uric acid in nondiabetic people mark pro-inflammatory state and HDL dysfunction and independently predicts coronary disease显示文摘 | Altan Onat Günay Can Ender ?rnek Servet Altay Murat Yüksel Evin Ademo?lu | 2013 | Clinical Rheumatology2013，，： | 1 |
| 3 | OR/MS research in disaster operations management显示文摘 | Altay N Green Ⅲ W G | 2006 | European Journal of Operations Research2006，175，： | 1 |
| 4 | The consistent Mindlin's thermopiezoelectric equations and the principle of virtual work 显示文摘 | ALTAY G CENGIZ D KMECI M | 2005 | Mechanics Research Communications2005，32，2： | 1 |
| 5 | Predictive value of red cell distribution width in intrahospital mortality and postintervention thrombolysis in myocardial infarction flow in patients with acute anterior myocardial infarction显示文摘 | Ilhan E Güven TS Altay S | 2012 | Coron Artery Dis2012，23，7： | 1 |
| 6 | OR/MS Research in Disaster OperationsManagement 显示文摘 | Altay N Green III W G | 2006 | European Journal of Operational Research2006，175，1： | 1 |
| 7 | A study on the seismic behavior of a retrofitted building based on nonlinear static and dynamic analyses显示文摘This study describes the seismic performance of an existing five storey reinforced concrete building which represents the typical properties of low-rise non-ductile buildings in Turkey. The effectiveness of shear walls and the steel bracings in retrofitting the building was examined through nonlinear static and dynamic analyses. By using the nonlinear static analysis, retrofitted buildings seismic performances under lateral seismic load were compared with each other.Moreover, the performance points and response levels of the existing and retrofitting cases were determined by way of the capacity-spectrum method described in ATC-40 (1996). For the nonlinear dynamic analysis the records were selected to represent wide ranges of duration and frequency content. Considering the change in the stiffness and the energy dissipation capacities, the performance of the existing and retrofitted buildings were evaluated in terms of story drifts and damage states.It was found that each earthquake record exhibited its own peculiarities, dictated by frequency content, duration, sequence of peaks and their amplitude. The seismic performance of retrofitted buildings resulted in lower displacements and higher energy dissipation capacity depending mainly on the properties of the ground motions and the retrofitting strategies. Moreover,severe structural damage (irreparable or collapse) was observed for the existing building. However, buildings with retrofit alternatives exhibited lower damage levels changing from no damage to irreparable damage states. | Esra Mete Güneyisi Gülay Altay | 2005 | Earthquake Engineering and Engineering Vibration2005，4，1： | 1 |
| 8 | Investigation of norovirus infection incidence among 0-5 years old children with acute gastroenteritis admitted to two different hospitals in ankara, Turkey 显示文摘 | Altay A Bozday G Meral M | 2013 | Article Turkish2013，47，1： | 1 |
| 9 | OR/MS research in disaster operations management 显示文摘 | ALTAY N GREEN W G | 2006 | European Journal of Operational Research2006，175，1： | 1 |
| 10 | Variational principles and vibrations of a functionally graded plate 显示文摘 | Altay G Dokmeci M C | 2005 | Computers and Structures2005，83，3： | 1 |
| 11 | OR/MS Research in Disaster Operations Management显示文摘 | Altay N Green W G | 2006 | European Journal of Operational Research2006，，175： | 1 |
| 12 | Finite element model- ing of bolted steel connections designed by double channel显示文摘 | Yorgun C Dalci S Altay G A | 2004 | Computers and Structures2004，82，2930： | 1 |
| 13 | Structural influence of gene networks on their inference:analysis of C3NET显示文摘 | ALTAY G EMMERT-STREIB F | 2011 | Biol Direct2011，，6： | 1 |
| 14 | OR/MS research in disaster operations management显示文摘 | Altay N Green W G | 2006 | European Journal of Operational Research2006，175，： | 1 |
| 15 | Finite element modeling of bolted steel connections designed by double channel显示文摘 | Yorgun C Dald S Altay G A | 2004 | Computers & Structures2004，82，29： | 1 |
| 16 | Perinatal and maternal outcomes of fetal macrosomia 显示文摘 | Engin O Arzu C Altay G | 2001 | European Journal of Obstetrics & Gynecology and Reproductive Biology2001，99，2： | 1 |
| 17 | OR/MS research in disaster operations management显示文摘 | ALTAY N GREEN W G | 2006 | European journal of operational research2006，175，1： | 1 |
| 18 | Generalized Partial Feedback Based Orthogonal Space-time Block Coding显示文摘 | Sezgin A Altay G Paulraj A | 2009 | IEEE Trans Wireless Commun2009，8，6： | 1 |
| 19 | OR/MS research in dis-aster operations management显示文摘 | ALTAY N GREEN W G | 2006 | European Journal of Operational Research2006，175，1： | 1 |
| 20 | Does treatment affect the levels of serum Interleukin-6, Interleukin-8 and procalcitonin in diabetic foot infection? A pilot study显示文摘 | Fatma Aybala Altay ?rfan ?encan G?nül ?i?ek ?entürk Mustafa Altay Selda Güvenman Selman ünverdi Ziya Cibali A??kg?z | 2012 | Journal of Diabetes and Its Complications2012，，3： | 1 |
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