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| 1 | Peritoneal carcinomatosis of colorectal origin显示文摘Peritoneal carcinomatosis is,after liver metastases,the second most frequent cause of death in colorectal cancer patients and at the present time,is commonly inserted and treated as a stage Ⅳ tumour.Because there is no published data that outlines the impact of new therapeutic regimens on survival of patients with peritoneal surface diffusion,the story of carcinomatosis can be rewritten in light of a new aggressive approach based on the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Also if these treatment perhaps allow to obtain better results than standard therapies,we suggest,that a large prospective randomised control trial is needed to compare long-term and progression-free survival under the best available systemic therapy with or without cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. | Antonio Macrì Edoardo Saladino Vincenzo Bartolo Vincenzo Adamo Giuseppe Altavilla Epifanio Mondello Giovanni Condemi Angelo Sinardi Ciro Famulari | 2010 | World Journal of Gastrointestinal Oncology2010，2，2： | 3 |
| 2 | Evidence for a role of mitogen-activated protein kinases in the treatment of experimental acute pancreatitis显示文摘Acute pancreatitis(AP) is an inflammatory disease characterized by acute inflammation and necrosis of the pancreatic parenchyma. AP is often associated with organ failure, sepsis, and high mortality. The pathogenesis of AP is still not well understood. In recent years several papers have highlighted the cellular and molecular events of acute pancreatitis. Pancreatitis is initiated by activation of digestive enzymes within the acinar cells that are involved in autodigestion of the gland, followed by a massive infiltration of neutrophils and macrophages and release of inflammatory mediators, responsible for the local and systemic inflammatory response. The hallmark of AP is parenchymal cell necrosis that represents the cause of the high morbidity and mortality, so that new potential therapeutic approaches are indispensable for the treatment of patients at high risk of complications. However, not all factors that determine the onset and course of the disease have been explained. Aim of this article is to review the role of mitogen-activated protein kinases in pathogenesis of acute pancreatitis. | Natasha Irrera Alessandra Bitto Monica Interdonato Francesco Squadrito Domenica Altavilla | 2014 | World Journal of Gastroenterology2014，20，44： | 2 |
| 3 | Duodenal periampullary gan- gliocytic paraganglioma: report of two cases with immunohisto- chemical and ultrastructural study显示文摘 | Altavilla G Chiarelli S Fassina A | 2001 | Ultrastruct Pathol2001，25，2： | 1 |
| 4 | The reduction ol myocardi-al damage and leukocyte polymorphonuclear accumulation followingcoronary artery occlusion by the tyrosine kinase inhibitor tyrphostinAG 556显示文摘 | Altavilla D Squadrito F Campo GM | 2000 | Life Sci2000，67，21： | 1 |
| 5 | Serum levels of osteopro- tegerin and RANKL in patients with ST elevation acute myocardial infarction显示文摘 | Crisafulli A Mieari A Altavilla D | 2005 | Clin Science2005，109，10： | 1 |
| 6 | Tumor necrosis factor in myocardial ischemia and reperfusion 显示文摘 | Squadrito F Saitta A Altavilla D | 1993 | Cardiologia1993，38，1： | 1 |
| 7 | IRFI 042,a novel dual vitamin E-like antioxidant,inhibits activation of nuclear factor kappa B and reduces the inflammatory response in myocardial ischemia-reperfusion injury显示文摘 | Altavilla D Deodato B Campo GM | 2000 | Cardiovasc Res2000，47，3： | 1 |
| 8 | Detection of human papillomavirus in temporal bone inverted papilloma by polymerase chain reaction显示文摘 | Marioni G Altavilla G Busatto G | 2003 | Acta Otolaryngol2003，123，3： | 1 |
| 9 | Recombinant human erythropoietin stimulates angiogenesis and wound healing in the genetically diabetic mouse显示文摘 | Galeano M Altavilla D Cucinotta D | 2004 | Diabetes2004，53，9： | 1 |
| 10 | Efferent vagus stimulation blunts nuclear factor - kappa B activation and protects against hypovolemic hemorrhagic shock 显示文摘 | Guarini S Altavilla D Cainazzo MM | 2003 | Circulation2003，107，8： | 1 |
| 11 | Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome显示文摘 | Bitto A Altavilla D Bonaiuto A | 2009 | Endocrinol2009，200，3： | 1 |
| 12 | Food deprivation increases brain nitric oxide syn- thase and depresses brain serotonin levels in rats 显示文摘 | SQUADRITO F CALAPAI G ALTAVILLA D | 1994 | Neuropharmacology1994，33，1： | 1 |
| 13 | Evidence for a role of nuclear faetor-kappaB in acute hypovolem ic hemorrhagic shock显示文摘 | Altavilla D Saitta A Squadrito G | 2002 | Surgery2002，131，1： | 1 |
| 14 | Cardioprotection by the phytoestrogen genistein in experimental myocardial ischemia-reperfusion injury显示文摘 | Deodato B Altavilla D Squadrito G | 1999 | Br J Pharmacol1999，1，28： | 1 |
| 15 | Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn wounds 显示文摘 | GALEANO M ALTAVILLA D BITTO A | 2006 | Crit Care Med2006，34，4： | 1 |
| 16 | IRFI 042, a novel dual vitamin E - like antioxidant, inhibits activation of nuclear factor - kappaB and reduces the inflammatory response in myocardial ischemia - reperfusion injury 显示文摘 | Altavilla D Deodato B Campo GM | 2000 | Cardiovasc Res2000，47，3： | 1 |
| 17 | Efferent Vagal Fibre Stimulation Blunts Nuclear Factor-κB Activation and Protects Against Hypovolemic Hemorrhagic Shock显示文摘 | Salvatore Guarini Domenica Altavilla Maria-Michela Cainazzo Daniela Giuliani Albertino Bigiani Herbert Marini Giovanni Squadrito Letteria Minutoli Alfio Bertolini Rolando Marini Elena B. Adamo Francesco S. Venuti Francesco Squadrito | 2003 | Circulation: Journal of the American Heart Association2003，，8： | 1 |
| 18 | Erlotinib therapy in a patient with non-small-cell lung cancer and brain metastases显示文摘 | Altavilla G Arrigo C Santarpia MC | 2008 | J Neurooncol2008，90，1： | 1 |
| 19 | Serumlevels of osteprelegerinand RANKL in patients with ST elevation acute myocardial infarction显示文摘 | Crisafulli A Micari A Altavilla D | 2005 | Clin Sci(Lond)2005，109，4： | 1 |
| 20 | Protective effects of anti oxidant raxofe last in alcohol-induced liver disease in mice显示文摘 | ALTAVILLA D MARINI H SEM1NARA P | 2005 | Pharmacology2005，74，： | 1 |
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