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| 1 | Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD显示文摘AIM: To detect a possible association between the polymorphism of the (-670 A/G) Fas/Apo1 gene promoter and susceptibility to Crohn's disease (CD) and ulcerative colitis (UC) in the Tunisian population. METHODS: The (-670 A/G) Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS: Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of (-670 A/G) Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls (P corrected = 0.004 in CD patients and P corrected = 0.02 in UC patients, respectively). Analysis also showed a statistically significant association between genotype AA of the (-670 A/G) polymorphism and the ileum localization of the lesions (P corrected = 0.048) and between genotype GG and the colon localization (Pcorrected = 0.009). The analysis ofinflammatory bowel disease patients according to clinical behavior revealed no difference. CONCLUSION: Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population. | Walid Ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna Makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib Ben Abdallah Khaled Ayed Yousr Gorgi | 2009 | World Journal of Gastroenterology2009，15，29： | 3 |
| 2 | The concept of seasonal succession theory applied to phytoplankton through the coupling use of diversity index and rank- frequencies diagrams in a eutrophic ecosystem显示文摘 | ALEYA L DEVAUX J | 1992 | Int Rev Gesamt Hydrobiol1992，77，： | 1 |
| 3 | Molecular survey of latent pseudorabies virus infection in nervous tissues of slaugh- tered pigs by nested and real -time PCR 显示文摘 | Yoon H A Eo S K Aleyas A G | 2005 | J Microbiol2005，43，5： | 1 |
| 4 | Genetic co-transfer of CCR7 ligands enhances immunity and prolongs survival against virulent challenge of pseudorabies virus显示文摘 | Han YW Aleyas AG George JA Kim SJ Kim HK Yoo DJ Kang SH Eo SK | 2009 | Immunol Cell Biol2009，87，1： | 1 |
| 5 | Selected elemental compositon of the muscle tissue of three species of fish Tilapia niltica Cirrhina mrigala and Clarius batrachus from the fresh water Dhanmondi Lake in Bangladesh显示文摘 | Aleya Begum Md Nurul Amin | 2005 | Food Chemistry2005，，93： | 1 |
| 6 | Cytokine GM-CSF ge- netic adjuvant facilitates prophylactic DNA vaccine against pseud- orabies virus through enhanced immune responses显示文摘 | Yoon H A Aleyas A G George J A | 2006 | Microbiol Immunol2006，50，2： | 1 |
| 7 | The deter-ministic factors of the Microcysitis aeruginosa bloomsover a biyearly survey in the hypereutrophic reservoir ofVillerest(Roanne,France) 显示文摘 | Aleya L Desmolles F Michard M | 1994 | Arch Hydrobiol1994，，： | 1 |
| 8 | Seasonal variation of heavy metals in water, sediment and roach tissues in a landfill draining system pond (Etueffont, France)显示文摘 | Zohra Ben Salem Nicolas Capelli Xavier Laffray Grisey Elise Habib Ayadi Lotfi Aleya | 2014 | Ecological Engineering2014，，： | 1 |
| 9 | Selected elemental composition of the muscle tissue of three species of fish, Tilapia nilotica, Cirrhina mrigala and Clarius batrachus, from the fresh water Dhanmondi Lake in Bangladesh显示文摘 | Aleya B M Nurul A | 2005 | Food Chemistry2005，93，3： | 1 |
| 10 | Association of chemokine and chemokine receptor polymorphisms with activity degree of IBD in Tunisian patients显示文摘 | Gorgi Y Ben Aleya W Sfar I | | 0，，1： | 1 |
| 11 | Phosphorus exchanges between sediment and water in trophically different reservoirs显示文摘 | MHAMDI M A ALEYA L DEVAUX J | 1994 | Water Research1994，28，9： | 1 |
| 12 | Cytokine GM-CSF Genetic Adjuvant Facilitates Prophylactic DNA Vaccine Against Pseudorabies Virus Through Enhanced Immune Responses显示文摘 | Yoon H A Aleyas A G George J A | 2006 | Microbiol Immunol2006，50，2： | 1 |
| 13 | The Bioaeeumulation Performance of Reed and Cattails in a Constructed Treatment Wetland for Removal of Heavy Metals in Landfil ILeachate Treatment (Etueffont,Franee) 显示文摘 | Elise Grisey Xavier Laffray Oceane Contoz Eric Cavalli Jacque Mudry Log Aleya | 2012 | Water Air Soil Ponut2012，223，： | 1 |
| 14 | Investigation of pseudorabies virus latency in nervous tissues of seropositive pigs exposed to field strain显示文摘 | Yoon H A Eo S K Aleyas A G Cha S Y Lee J H Chae J S Jang H K Cho E G Song H J | 2006 | J Vet Med Sci2006，68，2： | 1 |
| 15 | Preconcentration of phthalic acid esters in water samples by Saccharomyces cerevisiae immobilized on silica gel显示文摘 | Hideyuki Katsumata Aleya Begum Satoshi Kaneco Tohru Suzuki Kiyohisa Ohta | 2003 | Analytica Chimica Acta2003，，2： | 1 |
| 16 | Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia显示文摘AIM:To assess the possible association between PTPN22(R620W) gene polymorphism and inflammatory bowel disease(IBD).METHODS:One hundred and sixty-four patients with IBD 105 Crohn's disease(CD) and 59 ulcerative colitis(UC) and 100 healthy controls were recruited.Genotyping of the PTPN22 gene 1858C→T polymorphism was performed by restriction fragment length polymorphism-polymerase chain reaction with Rsa Ⅰ digestion.RESULTS:The genotypic and allelic frequencies of(R620W) PTPN22 gene polymorphism reveal a significant association of the PTPN22 620-W allele with IBD,compared to the healthy control group(OR:17.81,95% CI:4.18-21.86,P = 0.00001).Nevertheless,nodifference in this polymorphism was found between CD and UC patients.No significant association was found between the frequencies of genotypes of the PTPN22 gene with either the clinical features such as sex,age,age at disease onset,and extent of colitis,or the production of serological markers(anti-Saccharomyces cerevisiae antibody in CD and perinuclear anti-neutrophil cytoplasmic antibody in UC).CONCLUSION:These observations confirm the association of IBD susceptibility with the PTPN22 1858T(620-W) allele in Tunisian patients. | Imen Sfar Walid Ben Aleya Leila Mouelhi Houda Aouadi Thouraya Ben Rhomdhane Mouna Makhlouf Salwa Ayed-Jendoubi Houda Gargaoui Taoufik Najjar Taieb Ben Abdallah Khaled Ayed Yousr Gorgi | 2010 | World Journal of Gastroenterology2010，16，4： | 1 |
| 17 | Polymor-phism in ICAM-1, PECAM-1, E-selectin, and L-selectingenes in Tunisian patients with inflammatory bowel disease显示文摘 | Khazen D Jendoubi-Ayed S Aleya WB | 2009 | Eur J Gastroenterol Hepatol2009，21，2： | 1 |
| 18 | Metals and metalloid bioconcentrations in the tissues of Typha latifolia grown in the four interconnected ponds of a domestic landfill site显示文摘The uptake of metals in roots and their transfer to rhizomes and above-ground plant parts(stems, leaves) of cattails(Typha latifolia L.) were studied in leachates from a domestic landfill site(Etueffont, France) and treated in a natural lagooning system. Plant parts and corresponding water and sediment samples were taken at the inflow and outflow points of the four ponds at the beginning and at the end of the growing season. Concentrations of As, Cd, Cr, Cu, Fe, Mn, Ni and Zn in the different compartments were estimated and their removal efficiency assessed, reaching more than 90% for Fe, Mn and Ni in spring and fall as well in the water compartment. The above-and below-ground cattail biomass varied from 0.21 to 0.85, and 0.34 to 1.24 kg dry weight/m^2, respectively, the highest values being recorded in the fourth pond in spring 2011. The root system was the first site of accumulation before the rhizome, stem and leaves. The highest metal concentration was observed in roots from cattails growing at the inflow of the system's first pond. The trend in the average trace element concentrations in the cattail plant organs can generally be expressed as: Fe > Mn > As > Zn > Cr > Cu > Ni > Cd for both spring and fall. While T. latifolia removes trace elements efficiently from landfill leachates, attention should also be paid to the negative effects of these elements on plant growth. | Zohra Ben Salem Xavier Laffray Ahmed Al-Ashoor Habib Ayadi Lotfi Aleya | 2017 | Journal of Environmental Sciences2017，29，4： | 1 |
| 19 | Assessment of the Eutrophication of Al-Massira Reservoir (Morocco) by Means of A Survey of the Biogeochemical Balance of Phosphate显示文摘 | Alaouimhamdi M Aleya L | 1995 | Hydrobiologia1995，297，1： | 1 |
| 20 | Selected elemental compositon of the muscle tissue of three species of fish:Tilapia niltica,Cirrhina mrigala and Clarius atrachus from the flesh water Dhanmondi Lake in Bangladesh显示文摘 | Aleya Begum Md Nurul Amin | 2005 | Food Chemistry2005，93，： | 1 |
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