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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Genetic influ- ences of adiponectin on insulin resistance, type 2 dia- betes, and cardiovascular disease显示文摘 | Claudia M Vincenzo T Alessandro D | 2007 | Diabetes2007，56，： | 1 |
| 3 | DNA and RNA binding properties of an arginine-based ' Extended Chiral Box' Peptide Nucleic Acid显示文摘 | Alessandro C Tullia T Roberto C | | 0，，02： | 1 |
| 4 | Bone marrow tramplantation for lymphoma CR1显示文摘 | Corrado T Alessandro MG | 2005 | Current opinion in oncology2005，17，： | 1 |
| 5 | Identification of the newly described Mycobacterium poriferae form tuberculous lesions of snakehead fish (Channa striatus) 显示文摘 | Enrico T Alessandro B Elena B | 1996 | Comp Immun Microbial Infect Dis1996，19，： | 1 |
| 6 | Nanophase fluo- rite-structured CeO2-zrO2 catalysts prepared by high-energy mechanical milling 显示文摘 | Alessandro Trovarelli Francesca Zamar Jordi Horca Carla de Leitenburg Giuliano Dolcetti Janos T Kiss | 1997 | Journal of Catalysis1997，169，2： | 1 |
| 7 | Catalytic properties of ceria and CeOE-Containing materials显示文摘 | Alessandro T | 1996 | Catalytic Reviews-Science and Engineering1996，38，4： | 1 |
| 8 | Optical biopsy of bone tissue:a step toward the diagnosis of bone pathologies显示文摘 | Antonio P Alessandro T Paola T | 2004 | Journal of Biomedical Optics2004，9，3： | 1 |
| 9 | Influence of the tool edge geometry on specific cutting energy at high-speed cutting显示文摘 | ALESSANDRO R R REGINALDO T C | 2007 | Journal of the Brazilian Society of Mechanical Sciences and Engineering2007，29，3： | 1 |
| 10 | Identification of the newly described Mycobacterium poriferae from tuberculous lesions of snakehead fish(Channa striatus)显示文摘 | Enrico T Alessandro B Elena B | 1996 | Comparative Immu- nology Microbiology and Infectious Diseases1996，19，1： | 1 |
| 11 | Genetic influences of adiponectin on insulin resistance,type2diabetes,and cardiovascular disease显示文摘 | Claudia M Vincenzo T Alessandro D | 2007 | Diabetes2007，56，5： | 1 |
| 12 | Hardwarein-the-Loop Approach for Redundant Bmshless Motor Control System显示文摘 | B Alessandro P Paolo T Luea M Matteo | 2006 | IECON 2006-32nd Annual Conference on IEEE Industrial Electronics2006，，： | 1 |
| 13 | Computed-tomo- graphic-guided biopsy of thoracic nodules: a revision of 583 lesions 显示文摘 | D' Alessandro V Parracino T Stranieri A | 2007 | Clin Ter2007，158，6： | 1 |
| 14 | C-reactive protein and etiological subtypes of cerebral infarction显示文摘 | Alessandro T Laura V | 2008 | Neurol Sci2008，29，4： | 1 |
| 15 | Fuzzy systems and approximation显示文摘 | Alessandro Zorat | 1997 | Fuzzy Sets and Systems1997，85，2： | 1 |
| 16 | Phase II study of a single pegfilgrastim injection as an adjunct to chemotherapy to mobilize stem cells into the peripheral blood of pretreated lymphoma patients显示文摘 | Alessandro I Monica T Francesca B | 2005 | Haematologica2005，90，2： | 1 |
| 17 | Computed-tomographic-guided biopsy of thoracic nodules:a revision of 583 lesions显示文摘 | D'Alessandro V Parracino T Stranieri A | 2007 | ClinTer2007，158，6： | 1 |
| 18 | The control of selectivity in benzene hydroxylation catalyzed by TS-1: the solvent effect and the role of crystallite size显示文摘 | Barbera D Cavani F Alessandro T D | 2010 | Journal of Catalysis2010，275，： | 1 |
| 19 | Retrospective study of a large population of patients with asymptomatic or minimally symptoatic raised serum creatine kinase levels显示文摘 | Alessandro P Lucia T Monica S | 2002 | J Neurol2002，249，3： | 1 |
| 20 | Hepatitis B and C virus infection, alcohol drinking, hepatocellular carcinoma: a case control study in Italy显示文摘 | Farucesco D Alessandro T Roberta C | 1997 | Hapatology1997，26，3： | 1 |
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