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| 1 | Visual acuity and endothelial cell density with respect to the graft thickness in Descemet's stripping automated endothelial keratoplasty: one year results显示文摘AIM: To evaluate the visual acuity and endothelial cell density according to the thickness in Descemet's stripping automated endothelial keratoplasty(DSAEK)one year after surgery.METHODS: DSAEK patients' data were reviewed. Thirty seven eyes of 37 patients who underwent DSAEK for pseudophakic bullous keratopathy(PBK) were included in this study. Graft thickness was measured with optical coherence tomography(OCT) 12 mo after DSAEK. Eyes were divided into 3 groups based on the graft thickness:thick(>200 μm), medium-thick(150-200 μm) and thin(<150 μm). Best corrected visual acuity(BCVA),endothelial cells density(ECD) and complications were assessed and comparisons were done between groups.RESULTS: Median thickness of postoperative grafts was 188(range 73-317 μm). There was no significant difference in age, sex, preoperative BCVA, or follow-up period between DSAEK groups. At postoperative 12 mo,mean BCVA was 0.28±0.10 in thick graft group, 0.52±0.08 in medium-thick graft group, and 0.72 ±0.06 in thin graft group. Thin grafts showed better postoperative BCVA as compared with the medium-thick and thick grafts(P =0.001). Thick graft group had 1637.44 ±88.19-mm2,medium thick graft had 1764.50±34.28-mm2 and thin graft group had 1845.30 ±65.62-mm2. Thin graft group had better ECD at 12 mo after surgery(P =0.001).CONCLUSION: Thin grafts after DSAEK ensure better visual rehabilitation. Eyes with thin grafts had significantly lesser loss of ECD compared to eyes withmedium-thick and thick grafts one year after surgery. | Banu Torun Acar Mehmet Orcun Akdemir Suphi Acar | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 3 |
| 2 | Comparison of contrast sensitivity and visual acuity between deep anterior lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus显示文摘AIM: To evaluate postoperative visual acuity and contrast sensitivity results following deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus (KC). METHODS: All the patients' records with KC who had PK or DALK surgery between May 2010 and May 2011 were retrospectively reviewed. Sixty patients who underwent successful corneal transplantation for KC: 30 eyes underwent DALK and 30 eyes underwent PK were included in this study. Preoperative and postoperative mean logarithm of the minimum angle of resolution (logMAR) uncorrected visual acuity (UCVA), logMAR best spectacle-corrected visual acuity (BSCVA) and intraocular pressure (IOP) were evaluated. Contrast sensitivity tests (CS) were done preoperative and 2 months after all sutures had removed. All surgeries were performed under regional anesthesia (retrobulbar anesthesia) by 1 surgeon (B.K.) who was experienced in penetrating and lamellar keratoplasty techniques. RESULTS: The mean age of the DALK group was 29.67±4.95 (range 18-40) years and the PK group was 28.7±3.53 (range 18-39) years. Preoperatively there was no significant difference in the logMAR UCVA, logMAR BSCVA and IOP between the DALK (1.281±0.56; 0.97±0.85; 12.07±2.12mmHg) and PK (1.34±0.21; 0.98±0.21; 13±2.12mmHg) groups. One-year after surgery there was no significant difference in the mean logMAR UCVA and IOP between the DALK (0.46±0.37; 11.73±2.1mmHg) and PK (0.38±0.21; 12±2.12mmHg) groups. The mean contrast sensitivity was evaluated by CC-100 Topcon LCD at 1.5, 2.52, 4.23, 7.10 and 11.91 cycles per degree (cs/deg) spatial frequencies before and 2 months after the all sutures had removed. CONCLUSION: All patients with keratoconus in both DALK and PK groups performed good visual function postoperatively. The mean contrast sensitivity increased considerably at all spatial frequencies compared with preoperative levels in the DALK and PK groups. The mean post-operative evaluation of contrast sensitivity measurements was not significantly different between the two groups. | Mehmet Orcun Akdemir Baran Kandemir Isil Bahar Sayman Cem Selvi OmerKamil Dogan | 2012 | International Journal of Ophthalmology(English edition)2012，5，6： | 3 |
| 3 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 4 | A comparison of fluid absorption during transurethral resection and transurethral vaporization for benign prostatic hyperplasia显示文摘 | CETINKAYA M OZTURK B AKDEMIR O et ai | 2000 | BJU Int2000，86，7： | 1 |
| 5 | Effect of reperfusion on p-wave duration and p-wave dispersion in acute myocardial infarction:primary angioplasty versus thrombolytic therapy显示文摘 | Akdemir R Ozhan H Gunduz H | 2005 | Ann Noninvasive Elec-trocardiol2005，，： | 1 |
| 6 | Spinal dural arteriovenous fistula andvenous aneurysm:an unusual ssociation显示文摘 | Inci S Akdemir P Ozgen T | 2003 | Surg Neurol2003，60，4： | 1 |
| 7 | Neuroprotective effects of propofol following global cerebral ischemia in rats 显示文摘 | Ergun R Akdemir G Sen S | 2008 | Neurosurg Rev2008，25，3： | 1 |
| 8 | Value of 18F-fluorodeoxyglucose uptake in positron emission tomography/computed tomography in predicting survival in multiple myeloma显示文摘 | Haznedar R Aki SZ Akdemir OU | | 0，，06： | 1 |
| 9 | Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria显示文摘 | Akdemir Evrendilek G | 2015 | Int J Food Microbiol2015，202，： | 1 |
| 10 | Single-Site Robotic Total Hysterectomy: Standardization of Technique and Surgical Outcomes显示文摘 | Fatih Sendag Ali Akdemir Burak Zeybek Asuman Ozdemir Ilkben Gunusen Mehmet Kemal Oztekin | 2014 | The Journal of Minimally Invasive Gynecology2014，，： | 1 |
| 11 | Is There a Relationship Between Chronic Periodontitis and Erectile Dysfunction?显示文摘 | Fatih O?uz Abubekir Eltas Ali Beytur Ender Akdemir Mustafa ?zay Uslu Ali Güne? | 2012 | The Journal of Sexual Medicine2012，，3： | 1 |
| 12 | Experimental study of a closed loop vertical ground source heat pump system显示文摘 | Arif Hepbasli Ozay Akdemir Ebru Hancioglu | 2003 | America Energy Conversion and Management2003，44，： | 1 |
| 13 | Neuroprotective effects of propofol following global cerebral ischemia in rats显示文摘 | Ergun R Akdemir G Sen S | 2002 | Neurosurg Rev2002，2，： | 1 |
| 14 | A compare-son of fluid absorption during transurethral resectionand transurethral bapor- ization for benign prostatic hy-pcrplasia显示文摘 | Cetinkaya M Ozturk B Akdemir et ai | 2000 | BJU Int2000，86，7： | 1 |
| 15 | Energy and exergy analysis of a ground source (geothermal) heat pump system显示文摘 | Hepbasli A Akdemir O | | 0，，05： | 1 |
| 16 | Submandibu- lar artery:Bilobed platysma myocutaneous flap for total lower lip reconstruction显示文摘 | Akdemir O Lineaweaver WC Celik S | 2014 | Crani Omaxillofac Surg2014，42，8： | 1 |
| 17 | Pseudohypoparathyroid-ism presenting with ventricular arrhythmia: a case report显示文摘 | Iskay S Akdemir I Yilmaz K | 2012 | J Clin Res Pediatr Endocrinol2012，4，1： | 1 |
| 18 | Malignant schwannoma of the sciatic nerve originating in a spinal plexiform neurofibroma associated with neurofibromatosis type 1-case report显示文摘 | Topsakal C Akdemir I Tiftikci M | 2001 | Neurol Med Chir(Tokyo)2001，41，11： | 1 |
| 19 | Processing of fruits and fruit juices by novel electrotechnologies显示文摘 | AKDEMIR E G BAYSAL T ICIER F | 2012 | Food Engineering Reviews2012，4，1： | 1 |
| 20 | The Technical and Financial Effects of Parenteral Supplementation with Selenium and Vitamin E during Late Pregnancy and the Early Lactation Period on the Productivity of Dairy Cattle显示文摘 | Bayril T Yildiz AS Akdemir F | 2015 | Asian-Australasian journal of animal sciences2015，28，8： | 1 |
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