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| 1 | Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis显示文摘 | Guruprasad P. Aithal James A. Thomas Philip V. Kaye Adam Lawson Stephen D. Ryder Ian Spendlove Andrew S. Austin Jan G. Freeman Linda Morgan Jonathan Webber | 2008 | Gastroenterology2008,,4: | 2 |
| 2 | Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications显示文摘 | Aithal GP Day CP Kesteven PJ | | 0,,: | 1 |
| 3 | Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarindose requirement and risk of bleeding complications显示文摘 | Aithal GP Day CP Kesteven PJ | 1999 | Lancet1999,353,9154: | 1 |
| 4 | Tonal masking level differences in Aboriginal school children : Implications for binaural interaction, auditory processing disorders and education 显示文摘 | Aithal V Yonovitz A Aithal S | 2006 | Aust New Zeal J Audiol2006,26,: | 1 |
| 5 | Risk of cardiovascular and cerebrovascular events in primary biliary cirrhosis: a population based cohort study显示文摘 | Solaymani Dodaran M Aithal G P Card T West J | 2008 | Am J Gastroen terol2008,103,: | 1 |
| 6 | Comparisons Between Numerical Model and Experiments for a Direct Current Plasma Flow显示文摘 | S. M. Aithal V. V. Subramaniam V. Babu | 1999 | Plasma Chemistry and Plasma Processing1999,,4: | 1 |
| 7 | Reconstruction of the distal radius by fibula following excision of giant cell tumor显示文摘 | Aithal VK Bhaskaranand K | 2003 | Int Orthop2003,27,2: | 1 |
| 8 | Case definition and pheno-type standardization in drug - induced liver injury 显示文摘 | Aithal GP> Watkins PB Andrade RJ * | 2011 | Clin PharmacolTher2011,89,6: | 1 |
| 9 | Non - singular boundary integTal equation im- plementation 显示文摘 | Cruse T A Aithal R | 1993 | Int J Numer Methods Eng1993,,2: | 1 |
| 10 | Reconstruction of the distal radius by fibula following excision of giant cell tumor显示文摘 | V. K. Aithal K. Bhaskaranand | 2003 | International Orthopaedics2003,,2: | 1 |
| 11 | Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis显示文摘 | Guruprasad P. Aithal James A. Thomas Philip V. Kaye Adam Lawson Stephen D. Ryder Ian Spendlove Andrew S. Austin Jan G. Freeman Linda Morgan Jonathan Webber | 2008 | Gastroenterology2008,,4: | 1 |
| 12 | Randomized, placebo -controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis显示文摘 | Aithal GP Thomas JA Kaye PV | 2008 | Gastroenterology2008,135,4: | 1 |
| 13 | Guidelines on the management of ascites in cirrhosis 显示文摘 | Moore KP Aithal GP | 2006 | Gut2006,55,6: | 1 |
| 14 | Guidelines on the management of asci- tes in cirrhosis显示文摘 | Moore KP Aithal GP | 2006 | Gut2006,55,6: | 1 |
| 15 | Comparisons between numerical model and experiments for a direct current plasma flow显示文摘 | Aithal S M Subramaniam V V | 1998 | Journal of of Applied Physics1998,84,7: | 1 |
| 16 | Guidelines on the management of ascites in cirrhosis显示文摘 | Moore KP Aithal GP | | 0,,6: | 1 |
| 17 | Genetic susceptibility to diclofenac - induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes 显示文摘 | Daly AK Aithal GP Leathart JB | 2007 | Gastroenterology2007,132,: | 1 |
| 18 | L-carnitine supplementation in non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘BACKGROUND Non-alcoholic fatty liver disease(NAFLD)dominates the landscape of modern hepatology.Affecting 25%of the general population,there is critical unmet need to identify broadly available,safe and cost-effective treatments.Cumulative evidence in animal and human models suggests that intrahepatic and skeletal muscle fatty acid oxidation is impaired in NAFLD,such that lipid accretion is not matched by efficient utilisation.L-carnitine is a crucial mediator of fatty acid metabolism in vivo,promoting mitochondrial lipidβ-oxidation and enhancing tissue metabolic flexibility.These physiological properties have generated research interest in L-carnitine as a potentially effective adjunctive therapy in NAFLD.AIM To systematically review randomised trials reporting effects of dietary L-carnitine supplementation on liver biochemistry,liver fat and insulin sensitivity in NAFLD.METHODS Search strategies,eligibility criteria and analytic methods were specified a priori(PROSPERO reference:CRD42018107063).Ovid MEDLINE,Ovid EMBASE,PubMed,Web of Science and the Cochrane Library were searched from their inception until April 2019.Outcome measures included serum concentrations of alanine and aspartate aminotransferase(ALT and AST),liver fat and insulin sensitivity assessed by the homeostasis model of insulin resistance(HOMA-IR).A random effects meta-analysis was performed for,ALT,AST and HOMA-IR measures separately.Between-study heterogeneity was measured using I2 statistics.RESULTS Five eligible randomised trials were included in the qualitative and quantitative synthesis(n=338).All of the 5 included trials assessed the effect of L-carnitine on serum ALT,identified from Italy,South Korea and Iran.Weighted mean difference(WMD)for ALT between L-carnitine and control groups after intervention was-25.34 IU/L[95%CI:-41.74-(-8.94);P=0.002].WMD for AST between L-carnitine and control groups was-13.68 IU/L(95%CI:-28.26-0.89;P=0.066).In three studies(n=204),HOMA-IR was evaluated.WMD for HOMA-IR between L-carnitine and control groups was-0.74 units[95%CI:-1.02-(-0.46);P<0.001].Two studies using validated outcome measures reported a significant reduction in liver fat in L-carnitine vs control groups post-intervention(P<0.001).CONCLUSION Pooled results indicate that L-carnitine supplementation attenuates ALT,liver fat and insulin resistance in NAFLD cohorts,confirming a beneficial effect of Lcarnitine for a highly prevalent condition with a growing economic burden. | Prarthana Thiagarajan Jane Chalmers Lu Ban Douglas Grindlay Guruprasad P Aithal | 2020 | World Journal of Meta-Analysis2020,8,1: | 1 |
| 19 | In vitro biomechanical properties of linear,circular, and hybrid external skeletal fixation devices for use in large ruminants显示文摘 | Singh GR Aithal HP Saxena RK | 2007 | Vet Surg2007,36,: | 1 |
| 20 | Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis:are serial liver biopsies justified?显示文摘 | Aithal GP Haugk B Das S | 2004 | Aliment Pharmacol Ther2004,19,: | 1 |