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    题名 作者 年代 出处 被引量
1Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis显示文摘Guruprasad P. Aithal James A. Thomas Philip V. Kaye Adam Lawson Stephen D. Ryder Ian Spendlove Andrew S. Austin Jan G. Freeman Linda Morgan Jonathan Webber 2008Gastroenterology2008,,4:2
2Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications显示文摘Aithal GP Day CP Kesteven PJ 0,,:1
3Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarindose requirement and risk of bleeding complications显示文摘Aithal GP Day CP Kesteven PJ 1999Lancet1999,353,9154:1
4Tonal masking level differences in Aboriginal school children : Implications for binaural interaction, auditory processing disorders and education 显示文摘Aithal V Yonovitz A Aithal S 2006Aust New Zeal J Audiol2006,26,:1
5Risk of cardiovascular and cerebrovascular events in primary biliary cirrhosis: a population based cohort study显示文摘Solaymani Dodaran M Aithal G P Card T West J 2008Am J Gastroen terol2008,103,:1
6Comparisons Between Numerical Model and Experiments for a Direct Current Plasma Flow显示文摘S. M. Aithal V. V. Subramaniam V. Babu 1999Plasma Chemistry and Plasma Processing1999,,4:1
7Reconstruction of the distal radius by fibula following excision of giant cell tumor显示文摘Aithal VK Bhaskaranand K 2003Int Orthop2003,27,2:1
8Case definition and pheno-type standardization in drug - induced liver injury 显示文摘Aithal GP> Watkins PB Andrade RJ * 2011Clin PharmacolTher2011,89,6:1
9Non - singular boundary integTal equation im- plementation 显示文摘Cruse T A Aithal R 1993Int J Numer Methods Eng1993,,2:1
10Reconstruction of the distal radius by fibula following excision of giant cell tumor显示文摘V. K. Aithal K. Bhaskaranand 2003International Orthopaedics2003,,2:1
11Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis显示文摘Guruprasad P. Aithal James A. Thomas Philip V. Kaye Adam Lawson Stephen D. Ryder Ian Spendlove Andrew S. Austin Jan G. Freeman Linda Morgan Jonathan Webber 2008Gastroenterology2008,,4:1
12Randomized, placebo -controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis显示文摘Aithal GP Thomas JA Kaye PV 2008Gastroenterology2008,135,4:1
13Guidelines on the management of ascites in cirrhosis 显示文摘Moore KP Aithal GP 2006Gut2006,55,6:1
14Guidelines on the management of asci- tes in cirrhosis显示文摘Moore KP Aithal GP 2006Gut2006,55,6:1
15Comparisons between numerical model and experiments for a direct current plasma flow显示文摘Aithal S M Subramaniam V V 1998Journal of of Applied Physics1998,84,7:1
16Guidelines on the management of ascites in cirrhosis显示文摘Moore KP Aithal GP 0,,6:1
17Genetic susceptibility to diclofenac - induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes 显示文摘Daly AK Aithal GP Leathart JB 2007Gastroenterology2007,132,:1
18L-carnitine supplementation in non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘BACKGROUND Non-alcoholic fatty liver disease(NAFLD)dominates the landscape of modern hepatology.Affecting 25%of the general population,there is critical unmet need to identify broadly available,safe and cost-effective treatments.Cumulative evidence in animal and human models suggests that intrahepatic and skeletal muscle fatty acid oxidation is impaired in NAFLD,such that lipid accretion is not matched by efficient utilisation.L-carnitine is a crucial mediator of fatty acid metabolism in vivo,promoting mitochondrial lipidβ-oxidation and enhancing tissue metabolic flexibility.These physiological properties have generated research interest in L-carnitine as a potentially effective adjunctive therapy in NAFLD.AIM To systematically review randomised trials reporting effects of dietary L-carnitine supplementation on liver biochemistry,liver fat and insulin sensitivity in NAFLD.METHODS Search strategies,eligibility criteria and analytic methods were specified a priori(PROSPERO reference:CRD42018107063).Ovid MEDLINE,Ovid EMBASE,PubMed,Web of Science and the Cochrane Library were searched from their inception until April 2019.Outcome measures included serum concentrations of alanine and aspartate aminotransferase(ALT and AST),liver fat and insulin sensitivity assessed by the homeostasis model of insulin resistance(HOMA-IR).A random effects meta-analysis was performed for,ALT,AST and HOMA-IR measures separately.Between-study heterogeneity was measured using I2 statistics.RESULTS Five eligible randomised trials were included in the qualitative and quantitative synthesis(n=338).All of the 5 included trials assessed the effect of L-carnitine on serum ALT,identified from Italy,South Korea and Iran.Weighted mean difference(WMD)for ALT between L-carnitine and control groups after intervention was-25.34 IU/L[95%CI:-41.74-(-8.94);P=0.002].WMD for AST between L-carnitine and control groups was-13.68 IU/L(95%CI:-28.26-0.89;P=0.066).In three studies(n=204),HOMA-IR was evaluated.WMD for HOMA-IR between L-carnitine and control groups was-0.74 units[95%CI:-1.02-(-0.46);P<0.001].Two studies using validated outcome measures reported a significant reduction in liver fat in L-carnitine vs control groups post-intervention(P<0.001).CONCLUSION Pooled results indicate that L-carnitine supplementation attenuates ALT,liver fat and insulin resistance in NAFLD cohorts,confirming a beneficial effect of Lcarnitine for a highly prevalent condition with a growing economic burden.Prarthana Thiagarajan Jane Chalmers Lu Ban Douglas Grindlay Guruprasad P Aithal 2020World Journal of Meta-Analysis2020,8,1:1
19In vitro biomechanical properties of linear,circular, and hybrid external skeletal fixation devices for use in large ruminants显示文摘Singh GR Aithal HP Saxena RK 2007Vet Surg2007,36,:1
20Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis:are serial liver biopsies justified?显示文摘Aithal GP Haugk B Das S 2004Aliment Pharmacol Ther2004,19,:1
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