| 2 | Etiological agents causing leptospirosis in Sri Lanka:A review显示文摘Objective:To systematically review the etiological agent causing human leptospirosis in Sri Lanka.Methods:Published ailicles on leptospirosis and Leptospira in Sri Lanka were all reviewed to determine serovar,strain and species level indentification of Leptospira.After screening process.74 full text articles/reports were reviewed and among of them.12 published papers describing isolation of Leptospira from Sri Lankan patients/animals.5 molecular epidemiology papers on newer typing methods citing Sri Lanka isolates,with a descriptions of the isolates and 6 published papers reporting PCR based species level identification were identified.Results:Published literature showed that more than 40 strains classified under at least 20 serovars and 10 serogroups have been isolated from Sri Lanka.These isolates belong to four species,namely.Leptospira interrogans,Leptospira kirscluneri.Leptospira borgpetersenii,and Leptospira sanlarosai.In addition.recent studies on direct patient samples without culture and isolation showed Leptospira from Leptospira weilli is also circulating in Sri Lanka.Mulli locus sequence typing showed L3 genotypes of Leptospira from Sri Lankan isolates.Conclusions:This review shows the diversity of Leptospira in Sri Lanka,but culture isolation data has not been published in Sri Lanka during last 30 years. | Chamidri Naotunna Suneth Buddhika Agampodi Thilini Chanchala Agampodi | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，4： | 1 |
| 6 | The 2013 measles outbreak in Sri Lanka: experience from a rural district and implications for measles elimination goals显示文摘Background:Sri Lanka was the first country in the Southeast Asian region to achieve its measles elimination goal in 2011.In 2012,the measles immunization schedule changed from a measles vaccine at 9 months to a measles,mumps and rubella vaccine at 12 months.However in 2013,Sri Lanka reported its worst recent outbreak of measles.This study investigated a part of this outbreak in order to describe its epidemiology.Methods:A prospective study was carried out at the university medical unit of the Teaching Hospital,Anuradhapura(THA),the third largest hospital in Sri Lanka,from October 2013 until March 2014.An epidemiological profile of patients was constructed,case confirmation was done on all suspected cases and the basic demographic details of these suspected cases were obtained from the available records.Results:From January 2013 to March 2014,101 measles suspects were admitted to the THA.Until June 2013,all suspected cases were aged below 12 months of age.During the study period(15 months),the total number of patients aged below 9 months,9 to 12 months,1 to 11 years,12–29 years and over 29 years were 10(9.9%),11(10.9%),6(5.9%),37(36.6%)and 36(35.6%),respectively(data missing-1).Out of the 33 patients clinically suspected,32 tested positive for measles.Common clinical features included:fever(n=33,100%),maculopapular rash(n=33),conjunctivitis(n=31),posterior cervical lymphadenopathy(n=23)and Koplik’s spots(n=8).Features suggestive of pneumonia were observed among 30(90.9%)patients and 26(78.8%)had diarrhoea.Two patients(6.1%)who developed severe pneumonia received care at an intensive care unit due to respiratory difficulties.Out of 33 patients,15(45.5%)had prior immunization for measles,two(6.1%)reported that they never had a measles immunization and 16(48.5%)were unsure about their immunization status.Out of those who reported they were previously immunized,11(73.3%)belonged to the age group of 12–29 years.Conclusion:Because the first cases of this outbreak were infants,an increase in susceptible infants due to the change in the vaccine schedule could partly explain the outbreak. | Niroshana Jathun Dahanayaka Sithumini Pahalagamage Ranjan Madushanka Ganegama Prasanna Weerawansa Suneth Buddhika Agampodi | 2015 | Infectious Diseases of Poverty2015，4，1： | 0 |
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