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| 1 | Impact of endoscopic ultrasound-guided fine needle biopsy for diagnosis of pancreatic masses显示文摘AIM: To evaluate the diagnostic accuracy of histologi- cal evaluation of pancreatic tissue samples obtained by a modified method for recovering and processing the endoscopic ultrasound (EUS)-guided fine needle aspira- tion (FNA) material in the differential diagnosis of pan- creatic solid masses. METHODS: Sixty-two consecutive patients with pan- creatic masses were prospectively studied. EUS was performed by the linear scanning Pentax FG-38UX ech- oendoscope. Three FNAs (22G needle) were carried out during each procedure. The materials obtained with first and second punctures were processed for cytological study. Materials of the third puncture were recovered into 10% formol solution by careful injection of saline so- lution through the needle, and processed for histological study. RESULTS: Length of the core specimen obtained for his- tological analysis was 6.5 ± 5.3 mm (range 1-22 mm). Cytological and histological samples were considered as adequate in 51 (82.3%) and 52 cases (83.9%), respec- tively. Overall sensitivity of both pancreatic cytology and histology for diagnosis of malignancy was 68.4%. Con- trary to cytology, histology was able to diagnose tumours other than adenocarcinomas, and all cases of inflamma- tory masses. Combination of cytology and histology al- lowed obtaining an adequate sample in 56 cases (90.3%), with a global sensitivity of 84.21%, specificity of 100% and an overall accuracy of 90.32%. The complication rate was 1.6%.CONCLUSION: Adequate pancreatic core specimens forhistological examination can be obtained by EUS-guided FNA. This technique is mainly useful for the diagnosis of different types of pancreatic tumours and evaluation of benign diseases. | Julio Iglesias-Garcia Enrique Dominguez-Munoz Antonio Lozano-Leon Ihab Abdulkader Jose Larino-Noia Jose Antunez Jeronimo Forteza | 2007 | World Journal of Gastroenterology2007，13，2： | 17 |
| 2 | Rapid on-site evaluation of endoscopic-ultrasound-guided fine-needle aspiration diagnosis of pancreatic masses显示文摘Endoscopic ultrasound(EUS)has become an essential tool for the study of pancreatic diseases.Specifically,EUS plays a pivotal role evaluating patients with a known or suspected pancreatic mass.In this setting,differential diagnosis remains a clinical challenge.EUSguided fine-needle aspiration(FNA)and fine-needle biopsy(FNB)have been proven to be safe and useful tools in this setting.EUS-guided FNA and FNB,by obtaining cytological and/or histological samples,are able to diagnose pancreatic lesions with high sensitivity and specificity.In this context,several methodological features,trying to increase the diagnostic yield of EUS-guided FNA and FNB,have been evaluated.In this review,we focus on the role of rapid on-site evaluation(ROSE).From data reported in the literature,ROSE may increase diagnostic yield of EUS-FNA specimens by10%-30%,and thus,diagnostic accuracy.However,we should point out that many recent studies have reported adequacy rates of>90%without ROSE,indicating that,perhaps,at high-volume centers,ROSE may not be indispensable to achieve excellent results.The use of ROSE can be considered important during the learning curve of EUS-FNA,and also in hospital with diagnostic accuracy rates<90%. | Julio Iglesias-Garcia Jose Lario-Noia Ihab Abdulkader J Enrique Domínguez-Muoz | 2014 | World Journal of Gastroenterology2014，20，28： | 16 |
| 3 | Feasibility and yield of a novel 22-gauge histology EUS needle in patients with pancreatic masses: a multicenter prospective cohort study显示文摘 | Alberto Larghi Julio Iglesias-Garcia Jan-Werner Poley Geneviève Monges Maria Chiara Petrone Guido Rindi Ihab Abdulkader Paolo Giorgio Arcidiacono Guido Costamagna Katharina Biermann Erwan Bories Claudio Doglioni J. Enrique Dominguez-Mu?oz Cesare Hassan Ma | 2013 | Surgical Endoscopy2013，，10： | 3 |
| 4 | Rapid improvement in post-infectious gastroparesis symptoms with mirtazapine显示文摘We report the case of a 34-year-old woman with severe post-infectious gastroparesis who was transferred from an outside medical facility for a second opinion regarding management.This patient had no prior history of gastrointestinal symptoms.However,in the aftermath of a viral illness,she developed two months of intractable nausea,vomiting,and oral intake intolerance that resulted in numerous hospitalizations for dehydration and electrolyte disturbances.A solid-phase gastric emptying scan had confirmed delayed emptying,confirming gastroparesis.Unfortunately,conventional pro-kinetic agents and numerous anti-emetic drugs provided little or no relief of the patient’s symptoms.At our institution,the patient experienced a cessation of vomiting,reported a significant reduction in nausea,and toler-ated oral intake shortly after taking mirtazapine.Based on mirtazapine’s primary action as a serotonin(5-HT)1a receptor agonist,we infer that this receptor system mediated the clinical improvement through a combination of peripheral and central neural mechanisms.This report highlights the potential utility of 5-HT1a agonists in the management of nausea and vomiting.We conclude that mirtazapine may be effective in treating symptoms associated with non-diabetic gastroparesis that are refractory to conventional therapies. | Shinjini Kundu Shari Rogal Abdulkader Alam David J Levinthal | 2014 | World Journal of Gastroenterology2014，20，21： | 3 |
| 5 | Quantitative Endoscopic Ultrasound Elastography: An Accurate Method for the Differentiation of Solid Pancreatic Masses显示文摘 | Julio Iglesias–Garcia Jose Larino–Noia Ihab Abdulkader Jeronimo Forteza J. Enrique Dominguez–Munoz | 2010 | Gastroenterology2010，，4： | 3 |
| 6 | EUS elastography for the characterization of solid pancreatic masses显示文摘 | Julio Iglesias-Garcia Jose Larino-Noia Ihab Abdulkader Jeronimo Forteza J. Enrique Dominguez-Munoz | 2009 | Gastrointestinal Endoscopy2009，，6： | 3 |
| 7 | Long-term follow-up of patients after acute kidney injury:patterns of renal functional recovery显示文摘 | Macedo E Zanetta DM Abdulkader RC | | 0，，05： | 1 |
| 8 | Cyclooxy- genase-2 in normal, hyperplastic and neoplastic follicular cells of the human thyroid gland显示文摘 | Garcia-Gonzales M Abdulkader I Bouqete AV | 2005 | Virchows Arch2005，447，1： | 1 |
| 9 | Signetringcell carcinomapresentingin theuterinecervix: re- port of aprinlaryand metastatic cases 显示文摘 | Suglrez Pearanda J M Abdulkader I Bar6n Duarte F J | 2007 | Int J Gynecol Paihol2007，26，3： | 1 |
| 10 | Signet-ring cell carcinoma presenting in the uterine cervix: report of a primary and 2 metastatic cases 显示文摘 | Su6rez-Penaranda JM Abdulkader I Bar6n-Duarte FJ | 2007 | lnt J Gynecol Pathol2007，26，3： | 1 |
| 11 | Time-dependent effects of fatty acids on skeletal muscle metabolism 显示文摘 | Hirabara SM Silveira LR Abdulkader F | 2007 | J Cell Physiol2007，210，1： | 1 |
| 12 | Murad,Greating a GIS application for retail centers in Jeddah city显示文摘 | AbdulKader A | 2003 | International Journal of Applied Earth Observation and Geoinformation2003，4，： | 1 |
| 13 | Classification of vasculitis:EMA classification using CHCC 2012 definitions显示文摘 | Abdulkader R Lane SE Scott DG | 2013 | Ann Rheum Dis2013，72，： | 1 |
| 14 | Nasal and bronchial response to exercise in children with seasonal allergic rhinitis out of the pollen season显示文摘 | Koray Harmanc? Bar?s Urhan Hülya An?l Abdulkad?r Kocak | 2015 | Int Forum Allergy Rhinol2015，，： | 1 |
| 15 | Nephrotoxicity of Insect and Spider Venoms in Latin America显示文摘 | Abdulkader RC Barbaro KC Barros EJ | 2008 | Semin Nephrol2008，28，4： | 1 |
| 16 | Cell - cycle - associated markers and clinical outcome in human epithelial cancers : a tissue microarray study 显示文摘 | Abdulkader I Sanchez L Cameselle - Teijeiro J | 2005 | Oncol Rep2005，14，6： | 1 |
| 17 | Pathological changes related to Imatinib treatment in a patient with a metastatic gastrointestinal stromal tumour显示文摘 | Abdulkader I Cameselle T J Forteza J | 2005 | Histopathology2005，46，4： | 1 |
| 18 | Malignant mixed mesodrmal tumors:biology and clinical aspects显示文摘 | Gourley C Nafussi AA Abdulkader Metal | 2002 | Eur J Cancer2002，38，11： | 1 |
| 19 | Creating a GIS application for retail centers in Jeddah city 显示文摘 | AbdulKader A Murad | 2003 | International Journal of Applied Earth Observation and Geoinformation2003，4，4： | 1 |
| 20 | Thermoplastic starch plasticized by an ionic liquid 显示文摘 | Abdulkader Sankri Abdellah Arhaliass Isabelle Dez | 2010 | Carbohydrate Polymers2010，82，2： | 1 |
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