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| 1 | Lipid-Rich Variant of Pancreatic Endocrine Neoplasms显示文摘 | Rajendra Singh Olca Basturk David S Klimstra Giuseppe Zamboni Runjan Chetty Sanaa Hussain Stefano La Rosa Asli Yilmaz Paola Capelli Carlo Capella Jeanette D Cheng N Volkan Adsay | 2006 | The American Journal of Surgical Pathology2006，，2： | 2 |
| 2 | Laryngeal mucoepidermoid carcinoma: Report of two cases 显示文摘 | ASLI B C BERNA U C HUSEYIN S | 2006 | Auris Nasus Larynx2006，33，： | 1 |
| 3 | Effect of probiotics, yeast, vitamin E and vitamin C supplements on performance and immune response of laying hen during high environmental temperature显示文摘 | Asli M M Hosseini S A Lotfollahian H | 2007 | Pouh Sci2007，6，12： | 1 |
| 4 | Berry marinadesenhance oxidative stability of herring fillets 显示文摘 | Sampels S Asli M Vogt G | 2010 | Journal of Agricultural and Food Chemistry2010，58，12： | 1 |
| 5 | Oxidative-antioxidative systems and their relation with serum S100 B levels in patients with schizophrenia:Effects of short term antipsychotic treatment显示文摘 | Asli S Selcuk K Cengiz Ak | 2007 | Progress in Neuro-Psychopharmacol & Biol Psychiatry2007，31，6： | 1 |
| 6 | Complete supine per- cutaneous nephrolithotomy (csPCNL) in patients with and with- out a history of stone surgery: safety and effectiveness of csPCNL 显示文摘 | Falahatkar S Asli MM Emadi SA | 2011 | Uroi Res2011，39，： | 1 |
| 7 | High efficiency time re- dundant hardened latch for reliable circuit design 显示文摘 | ASLI R N SHIRINZADEH S | 2013 | Journal of Electronic Testing2013，29，4： | 1 |
| 8 | Antagomism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in th liver 显示文摘 | ELMEN J ASLI S MADS B | 2008 | Nucleic Acids Res2008，36，： | 1 |
| 9 | Comparison of technetium99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy:a preliminary study显示文摘 | Javadi H Asli IN Sennani S | 2011 | Hell J Nucl Med2011，14，： | 1 |
| 10 | Colloidal suspensions of clay or titanium dioxide nanoparticles can inhibit leaf growth and transpiration via physical effects on root water transport显示文摘 | Asli S Neumann M | | 0，，05： | 1 |
| 11 | MicroRNA expression in the adult mouse central nervous system显示文摘 | Mads B Asli S Morten M | 2008 | RNA2008，14，： | 1 |
| 12 | Colloidal suspensions of clay or titanium dioxide nanoparticles can inhibit leaf growth and transpiration via physical effects on root water transport 显示文摘 | Asli S Neumann M | 2009 | Plant Cell and Environment2009，32，5： | 1 |
| 13 | Induced fear reduces the ef- fectiveness of a placebo intervention on pain 显示文摘 | Lyby P S Forsberg J T Asli O | 2012 | Pain2012，153，5： | 1 |
| 14 | Complete supine percutaneous nephrolithotomy (csPCNL) in patients with and without a history of stone surgery:safety and effectiveness of csPCNL显示文摘 | Falahatkar S Asli MM Emadi SA | | 0，，4： | 1 |
| 15 | If Mathematics Were a Color 显示文摘 | Ozgian-koca S Asli | 2010 | Ohio Journal of School Mathematics2010，62，4： | 1 |
| 16 | Colloidal suspensions of clay or titanium dioxide nanopartieles can inhibit leaf growth and transpiration via physical effects on root water transport显示文摘 | Asli S Neumann P M | 2009 | Plant Cell and Environment2009，32，： | 1 |
| 17 | Relationship between MMP-1,MMP-9,TIMP-1,IL-6and risk factors,clinical presentation,ex-tent and severity of atherosclerotic coronary artery disease显示文摘 | Asli T Asife S Sehri E | 2011 | Open Cardio Med J2011，5，： | 1 |
| 18 | Inhibition of Ehrlich ascites carcinoma growth by melatonin:Studies with micro-CT显示文摘Melatonin is a versatile indolamine synthesized and secreted by the pineal gland in response to the photoperiodic information received by the retinohypothalamic signaling pathway.Melatonin has many benefits,such as organizing circadian rhythms and acting as a powerful hormone.We aimed to show the antitumor effects of melatonin in both in vivo and in vitro models through the mammalian target of rapamycin(mTOR)signaling pathway and the Argyrophilic Nucleolar Regulatory Region(AgNOR),using the Microcomputed Tomography(Micro CT).Ehrlich ascites carcinoma(EAC)cells were administered into the mice by subcutaneous injection.Animals with solid tumors were injected intraperitoneally with 50 and 100 mg/kg melatonin for 14 days.Volumetric measurements for the taken tumors were made with micro-CT imaging,immunohistochemistry(IHC),real-time polymerase chain reaction(PCR)and AgNOR.Statistically,the tumor tissue volume in the Tumor+100 mg/kg melatonin group was significantly lower than that in the other groups in the data obtained from micro-CT images.In the IHC analysis,the groups treated with Tumor+100 mg/kg melatonin were compared when the mTOR signaling pathway and factor 8(F8)expression were compared with the control group.It was determined that there was a significant decrease(p<0.05).Significant differences were found in the total AgNOR area/nuclear area(TAA/NA)ratio in the treatment groups(p<0.05).Furthermore,there were significant differences between the amount of mTOR mRNA for the phosphatidylinositol 3-kinase(PI3K),AKT Serine/Threonine Kinase(PKB/AKT)genes(p<0.05).Cell apoptosis was evaluated with Annexin V in an in vitro study with different doses of melatonin;It was observed that 100µg/mL melatonin dose caused an increase in the apoptotic cell death.In this study,we have reported anti-tumor effects of melatonin in cell culture studies as well as in mice models.Comprehensive characterization of the melatonin-mediated cancer inhibitory effects will be valuable in advancing our fundamental molecular understanding and translatability of pre-clinical findings to earlier phases of clinical trials. | SEHER YILMAZ ZÜLEYHA DOĞANYIĞIT MERT OCAK EVRIM SUNA ARIKAN SÖYLEMEZ ASLI OKAN OFLAMAZ SÜMEYYE UÇAR ŞÜKRÜATEŞ AMMAD AHMAD FAROOQI | 2024 | Oncology Research2024，32，1： | 0 |
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