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| 1 | Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease显示文摘AIM To determine how the auto-antibodies(Abs) profiles overlap in chronic hepatitis C infection(CHC) and autoimmune hepatitis(AIH) and correlate to liver disease.METHODS Levels of antinuclear Ab, smooth muscle antibody(SMA) and liver/kidney microsomal-1(LKM-1) Ab and markers of liver damage were determined in the sera of 50 patients with CHC infection, 20 AIH patients and 20 healthy controls using enzyme linked immunosorbent assay and other immune assays. RESULTS We found that AIH patients had more severe liver disease as determined by elevation of total Ig G, alkaline phosphatase, total serum bilirubin and serum transaminases and significantly higher prevalence of the three non-organ-specific autoantibodies(auto-Abs) than CHC patients. Antinuclear Ab, SMA and LKM-1 Ab were also present in 36% of CHC patients and related to disease severity. CHC cases positive for auto-Abs were directly comparable to AIH in respect of most markers of liver damage and total Ig G. These cases had longer disease duration compared with auto-Ab negative cases, but there was no difference in gender, age or viral load. KLM-1+ Ab CHC cases showed best overlap with AIH. CONCLUSION Auto-Ab levels in CHC may be important markers of disease severity and positive cases have a disease similar to AIH. Auto-Abs might have a pathogenic role as indicated by elevated markers of liver damage. Future studies will unravel any novel associations between these two diseases, whether genetic or other. | Kawa Amin Aram H Rasool Ali Hattem Taha AM Al-Karboly Taher E Taher Jonas Bystrom | 2017 | World Journal of Gastroenterology2017，23，8： | 5 |
| 2 | Adiponectin downregulation is associated with volume overload-induced myocyte dysfunction in rats显示文摘目的: Adiponectin 被报导了在在体积的病理学的室的改变,而是 adiponectin 的角色期间施加保护的效果导致超载的心失败遗体不清楚。在这研究,我们在心脏的 myocyte 上调查了 adiponectin 的效果在 rats.Methods 的可收缩的机能障碍追随者体积超载: 体积超载被 infrarenal 主动脉静脉 cava 通过手术在老鼠导致管。老鼠是在 2- 的静脉内地管理的 adenoviral adiponectin, 6 星期、 9 星期的后面的管。adiponectin, adiponectin 受体(AdipoR1/R2 和 T-cadherin ) 和 AMPK 活动的蛋白质表示用西方的污点分析被测量。孤立的室的 myocytes 在管以后的 12 个星期被准备检验 myocytes 和细胞内部的 Ca 2+ transient.Results 的可收缩的表演: A-V 管在浆液和心肌的 adiponectin 层次导致了重要减小,心肌的 adiponectin 受体(AdipoR1/R2 和 T-cadherin ) 层次,以及心肌的 AMPK 活动。与这些变化一致,孤立的 myocytes 在房间弄短和细胞内部的 Ca 2+ 展出了重要消沉短暂。adenoviral adiponectin 的管理显著地增加了浆液 adiponectin 层次并且阻止了 myocyte 在管老鼠的可收缩的机能障碍。而且,有 recombinant adiponectin 的孤立的 myocytes 的预告的处理(2.5 μ g/mL ) 显著地在管老鼠改进了他们的可收缩的性能,但是没在控制或 adenoviral 有效果管理 adiponectin 的 rats.Conclusion : 这些结果表明在 adiponectin downregulation 和体积之间的积极关联导致超载的室的改变。Adiponectin 在体积起一个保护的作用导致超载的心失败。 | Li-li WANG Dori MILLER Desiree WANDERS Gayani NANAYAKKARA Rajesh AMIN Robert JUDD Edward E MORRI-SON Ju-ming ZHONG | 2016 | Acta Pharmacologica Sinica2016，37，2： | 4 |
| 3 | SMILE intraoperative complications: incidence and management显示文摘AIM: To report the intraoperative complications associated with small incision lenticule extraction(SMILE) and their management. METHODS: This was a retrospective consecutive interventional clinical study, carried out on patients with myopia and myopic astigmatism, who underwent SMILE procedure. Type of intraoperative complications and their management were recorded. RESULTS: Our study comprised 282 eyes of 141 patients who were enrolled for SMILE surgeries. The intraoperative complications included lost vacuum(18 eyes, 6.38%), treatment decentration(6 eyes, 2.12%), wound bleeding(21 eyes, 7.45%), incomplete bubble separation(black islands)(3 eyes, 1.06%), the epithelial defects(15 eyes, 5.32%). Incision tear(27 eyes, 9.57%), lenticule adherence to the cap(6 eyes, 2.12%), and cap perforation occurred in 2 eyes(0.7%). CONCLUSION: Although SMILE is a promising technique for the correction of myopia and myopic astigmatism with predictable, efficient, safe refractive and visual outcomes, complications can occur. However, most of them are related to inexperience and are included in the learning curve of the technique. More studies with a bigger number of eyes are required to efficiently evaluate the intraoperative complications and standardize their management strategies. | Abdelmonem M Hamed Mohamed Amin Heikal Tarek T.Soliman Ahmed Daifalla Khaled E Said-Ahmed | 2019 | International Journal of Ophthalmology(English edition)2019，12，2： | 4 |
| 4 | A computational study of pressure effects on pollutant generation in gas turbine combustors显示文摘 | Amin E M Andrews G E Pourkashnian M | 1997 | Journal of Engineering for Gas Turbines and Power1997，119，： | 2 |
| 5 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 6 | Estimating saturated hydraulic conductivity in spatially variable fields using neural network ensembles 显示文摘 | KAMBAN P AMIN E BING C S | 2006 | Soil Science Society of America Journal2006，70，6： | 1 |
| 7 | Heat-treated milk differentiation by a sensitive lactulose assay显示文摘 | MARCONI E MESSIA M C AMINE A | 2004 | Food Chem2004，84，： | 1 |
| 8 | Unique homologous siRNA blocks hypoxia-induced VEGF upregulation in human corneal cells and inhibits and regresses murine corneal neovascularizatlon 显示文摘 | Singh N Higgins E Amin S | 2007 | Cornea2007，26，1： | 1 |
| 9 | Flt-1 intraceptors inhibit hypoxia-induced VEGF expression in vitro and corneal neovascularization in vivo显示文摘 | Singh N Amin S Richter E | | 0，，05： | 1 |
| 10 | Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change显示文摘 | Dhillon J Amin MB Selbs E | 2009 | Am J Surg Pathol2009，33，1： | 1 |
| 11 | Rho-kinase: regulation, (dys)function, and inhibition显示文摘 | Amin E Dubey BN Zhang SC | 2013 | Bioi Chern2013，394，11： | 1 |
| 12 | Cytotoxic Effect of Chitosan Based Nanocomposite Synthesized by Radiation: In Vitro Liver and Breast Cancer Cell Line显示文摘 | A. Abaza G. A. Mahmoud E. A. Hegazy M. Amin E Shoukry B. Elsheikh | 2018 | Journal of Pharmacy and Pharmacology2018，6，4： | 1 |
| 13 | Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change 显示文摘 | Dhillon J Amin MB Selbs E | 2009 | Am J Surg Patho12009，33，1： | 1 |
| 14 | Fh-1 intraceptors inhibit hypoxia-induced VEGF expression in vitro and comeal neovascularization in vivo 显示文摘 | SINGH N AMIN S RICHTER E | 2005 | Invest Ophthalmol Vis Sci2005，46，5： | 1 |
| 15 | Effect of Elastic Boundary Conditions on Morphotropic Pb (Zr, Ti) 03 Piezoelectrics 显示文摘 | Amin A Newnham R E Cross L E | 1986 | Phys Rev B1986，34，3： | 1 |
| 16 | Papillarycystic neoplasm of pancreas 显示文摘 | Poustchr Amin M Leonidas J G Valderrrama E | 1995 | Pediatr Radiol1995，25，7： | 1 |
| 17 | Removal of lead (Ⅱ) and copper (Ⅱ) from aqueous solution using pomegranate peel as a new adsorbent 显示文摘 | El-Ashtoukhy E S Z Amin N K Abdelwahab O | 2008 | Desalination2008，223，13： | 1 |
| 18 | Preoperative tyrosine kinase inhibition as an adjunct to debulking nephrec-tomy显示文摘 | Amin C Wallen E Pruthi RS | | 0，，04： | 1 |
| 19 | Biological treatment of industrial wastes in a photobioreactor显示文摘 | TAMER E AMIN M A OSSAMA E T | 2006 | Water Science Technology2006，53，11： | 1 |
| 20 | Electrochemical removal of phenol from oil refinery wastewater 显示文摘 | Abdelwahab O Amin N K E1-Ashtoukhy E S Z | 2009 | Journal of Hazar- dous Materials2009，163，23： | 1 |
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