|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases显示文摘AIM: To evaluate immunoexpression of cyclooxygenase-2 (COX-2) in primary gastric carcinomas and respective lymph node metastases. METHODS: Immunohistochemistry to analyze COX-2 expression was performed on tissue microarray slices obtained from 36 specimens of gastrectomy and satellite lymph nodes from patients with gastric carcinoma. RESULTS: Immunostaining was seen in most cases, and COX-2 expression was higher in lymph node me-tastases than in corresponding primary gastric tumors of intestinal, diffuse and mixed carcinomas, with a statistically signif icant difference in the diffuse histotype (P = 0.0108). CONCLUSION: COX-2 immunoexpression occurs frequently in primary gastric carcinomas, but higher expression of this enzyme is observed in lymph node metastases of the diffuse histotype. | Paulo RC Almeida Francisco VA Ferreira Cássio C Santos Francisco D Rocha-Filho Raul RP Feitosa Esther AA Falco Belise K Cavada Roberto CP Lima-Júnior Ronaldo A Ribeiro | 2012 | World Journal of Gastroenterology2012，18，8： | 14 |
| 2 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 3 | Biology teachers’ perceptions about Science-Technology-Society (STS) education显示文摘 | Cátia Bettencourt José Lopes Velho Patrícia Albergaria Almeida | 2011 | Procedia - Social and Behavioral Sciences2011，，： | 3 |
| 4 | Purification of metallurgical grade silicon by acid leaching显示文摘 | SANTOS I C GONCALVES A P SANTOS C S ALMEIDA M AFONSO M H CRUZ M J | 1990 | Hydrometallurgy1990，23，： | 1 |
| 5 | Improving hierarchical cluster analysis: a new method with outlier detection and automatic clustering显示文摘 | ALMEIDA J A S BARBOSA L M S PAIS A A C C | 2007 | Chemometrics and Intelligent Labora- tory Systems2007，87，2： | 1 |
| 6 | ,Cytogenetic investigation in a Brazilian population living in an area of high natural radioactivity显示文摘 | BarcinskiMA Do Céu Abreu M De Almeida JC | 1975 | Am J Hum Genet1975，27，6： | 1 |
| 7 | Near-surface circulation and kinetic energy in the tropical Indian Ocean derived from Lagrangian drifters显示文摘 | SHENOI S S C SAJI P K ALMEIDA A M | 1999 | Journal of Marine Research1999，57，6： | 1 |
| 8 | Use of different intertidal habitats by faunal communities in a temperate coastal lagoon显示文摘 | Almeida C Coelho R Silva M | 2008 | Estuar Coast Shelf Sci2008，80，3： | 1 |
| 9 | Ultrasound-assisted single-drop microextraction for the determination of cadmium in vegetable oils using high-resolution continuum source electrothermal atomic absorption spectrometry显示文摘 | ALMEIDA J S ANUNCIACAO T A BRANDAO G C | 2015 | Spectrochimica Acta Part B: Atomic Spectroscopy2015，107，： | 1 |
| 10 | A simple and effective inverse projection scheme for void distri- bution control in topology optimization 显示文摘 | Almeida S R M Paulino G H Silva E C N | 2009 | Structur- al and Multidisciplinary Optimization2009，39，4： | 1 |
| 11 | Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5,GATA4 and Tbx5显示文摘 | Linhares V L Almeida N A Menezes D C | 2004 | Cardiovasc Res2004，64，3： | 1 |
| 12 | Effectsof glycosylation on heparin binding and antithromhin activation by hep-arin显示文摘 | Pol-Fachin L Franco Becker C Almeida Guimaraes J | 2011 | Proteins2011，79，9： | 1 |
| 13 | Determination of chemical ox- ygen demand employed manganese as an environmentally friendly oxidizing reagent by a flow injection method based on microwave digestion and speeiation coupled to ICP -OES 显示文摘 | Almeida C A Savio M Gonzdlez P | 2013 | M ieroehemieal Journal: Devoted to the Application of Mieroteehniques in all Branches of Science2013，106，10： | 1 |
| 14 | Estrogen receptor-[alpha] signaling in osteoblast progenitors stimulates cortical bone accrual显示文摘 | Almeida Maria Iyer Srividhya Martin-Millan Marta Bartell Shoshana M Han Li Ambrogini Elena Onal Melda Xiong Jinhu Weinstein Robert S Jilka Robert L O’Brien Charles A Manolagas Stavros C | 2013 | Journal of Clinical Investigation2013，，1： | 1 |
| 15 | Biochemi- cal response in farmed mussel Perna perna transplanted to con- taminated sites on Santa Catarina Island, SC, Brazeil 显示文摘 | BAINY A C D ALMEIDA E A MULLER I C | 2000 | Ma- rine Environmental Research2000，50，12345： | 1 |
| 16 | Mental health among perimenopausal women attending a menopause clinic:possible association with premenstrual syndrome?显示文摘 | Novaes C Almeida OP de Melo NR | 1998 | Climacteric1998，，4： | 1 |
| 17 | Study of the quality of life in people with traumatic spinal cord injury显示文摘 | VALL J BRAGA V A DE ALMEIDA P C | 2006 | Arquivos de Neuro-Psiquiatria2006，64，2： | 1 |
| 18 | Study on high performance roller compacted concrete显示文摘 | BETTENCOURT RIBEIRO A C DE ALMEIDA I R | 2000 | Materials and Structures2000，33，6： | 1 |
| 19 | A PCR protocol using inl gene as a target for specific detection of listeria monocytogenes 显示文摘 | P F Almeida R C C Almeida | 2000 | Food Control2000，11，： | 1 |
| 20 | Developing ecotechnologies:A possibility to mininuze environmental impact in Southern Brazil显示文摘 | Giannetti B F Bonilla S H Almeida C M V B | 2004 | Journal of Cleaner Production2004，，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员